References
- Johnston S L, Pattermore P K, Sanderson G, , et al. Community study of role of viral infections in exacerbation of asthma in 9–11 year old children. BMJ 1995; 310:1225–1229. [PUBMED], [INFOTRIEVE]
- British Thoracic Society. Guidelines on the management of asthma. Thorax 1997; 52:S1–S21.
- Global Strategy for Asthma Management and Prevention. National Institutes of Health. National Health, Lung and Blood Institute. Revised 2002.
- Zora J A, Zimmerman D, Carey T L, O'Connell E J, Yunginger J W. Hypotalamic-pituitary-adrenal axis suppression after short-term, high-dose glucocorticoid therapy in children with asthma. J Allergy Clin Immunol 1986; 77:9–13. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Dolan L M, Keserwala H H, Holroyde J C, Fischer T J. Short-term, high-dose, systemic steroids in children with asthma: the effect on the hypotalamic-pituitary-adrenal axis. J Allergy Clin Immunol 1987; 80:81–87. [PUBMED], [INFOTRIEVE]
- Wolthers O, Pedersen S. Short-term linear growth in asthmatic children during treatment with prednisolone. BMJ 1990; 301:145–148. [PUBMED], [INFOTRIEVE]
- Gibson P G, Saltos N, Fakes K. Acute anti-inflammatory effects of inhaled budesonide in asthma. A randomized controlled trial. Am J Respir Crit Care Med 2001; 163:32–36. [PUBMED], [INFOTRIEVE], [CSA]
- Tsai Y0.0-G, Lee M-Y, Yang K D, , et al. A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma. J Pediatr 2001; 139:433–437. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Griffiths C. Steroids in exacerbations of asthma: tablets or inhalers?. Thorax 1996; 51:1071–1072. [PUBMED], [INFOTRIEVE]
- Hill J M. Nebulised corticosteroids in the treatment of asthma. Thorax 1999; 54:661–663. [PUBMED], [INFOTRIEVE]
- Volovitz B, Soferman R, Blau H, Nussinovitch M, Varsano I. Rapid induction of clinical response with a short-term high-dose starting schedule of budesonide nebulizing suspension in young children with recurrent wheezing episodes. J Allergy Clin Immunol 1998; 101:464–469. [PUBMED], [INFOTRIEVE], [CSA]
- Manjra A I, Price J, Lenney W, Hughes S, Barnacle H. Effect of nebulised fluticasone propionate compared with oral prednisolone in children with an acute exacerbation of asthma. Respir Med 2000; 94:1206–1214. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Edmonds M L, Camargo C A, Pollack C V, Rowe B H. The effectiveness of inhaled corticosteroids in the emergency department treatment of acute asthma: a meta-analysis. Ann Emerg Med 2002; 40:145–154. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Barnes N. Relative safety and efficacy of inhaled corticosteroids. J Allergy Clin Immunol 1998; 101:S460–S464. [PUBMED], [INFOTRIEVE], [CSA]
- O'Byrne P M, Pedersen S. Measuring efficacy and safety of different inhaled corticosteroid preparations. J Allergy Clin Immunol 1998; 102:879–886. [PUBMED], [INFOTRIEVE], [CSA]
- Barnes N C, Hallet C, Harris T A. Comparative efficacy and safety of fluticasone propionate at half microgram doses of budesonide and beclomethasone dipropionate in asthma: a meta analysis. Respir Med 1998; 92:95–104. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ferguson A C, Spier S, Manjra A, Versteegh F G.A, Mark S, Zhang P. Efficacy and safety of high-dose inhaled steroids in children with asthma: a comparison of fluticasone propionate to budesonide. J Pediatr 1999; 134:422–427. [PUBMED], [INFOTRIEVE]
- Polgar G, Promadhat V. Pulmonary Function Testing in Children: Techniques and Standards. Philadelphia: WB Saunders Co., 1971.
- Standardization of spirometry, 1994 update. American Thoracic Society. Am J Respir Crit Care Med 1995; 152:1107–1136. [CSA]
- Leflein J, Brown E, Hill M, , et al. Delivery of glucocorticoids by jet nebulization. Aerosol characteristics and output. J Allergy Clin Immunol 1995; 95:944–949. [PUBMED], [INFOTRIEVE], [CSA]
- Westlake W J. Bioequivalence testing—a need to rethink. Biometrics 1981; 37:591–593.
- de Benedictis F M, Boner A, Cavagni G, Caffarelli C, Ferraro L, Cantini L. Treating asthma in children with beclomethasone dipropionate: Pulvinal vs. Diskhaler. J Aerosol Med 2000; 13:35–41. [PUBMED], [INFOTRIEVE], [CSA]
- Connett G, Lenney W. Prevention of viral induced asthma attacks using inhaled budesonide. Arch Dis Child 1993; 68:85–87. [PUBMED], [INFOTRIEVE]
- Wilson N M, Silverman M. Treatment of acute, episodic asthma in preschool children using intermittent high dose inhaled steroids at home. Arch Dis Child 1990; 65:407–410. [PUBMED], [INFOTRIEVE]
- Sverdymyr J, Nyberg E, Asbrink-Nilsson E, Hedlin G. Intermittent treatment with inhaled steroids for deterioration of asthma due to upper respiratory tract infections. Acta Paediatr 1995; 84:884–888.
- Sano F, Cortez G K, Sole D, Naspitz C K. Inhaled budesonide for the treatment of acute wheezing and dyspnea in children up to 24 months old receiving intravenous hydrocortisone. J Allergy Clin Immunol 2000; 105:699–703. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Devidayal Singhi S, Kumar L, Jayshree M. Efficacy of nebulized budesonide compared to oral prednisolone in acute bronchial asthma. Acta Paediatr 1999; 88:835–840. [CROSSREF]
- Volovitz B, Bentur L, Finkelstein Y, Mansour J, Shalitin S, Nussinovitch M. Effectiveness and safety of inhaled corticosteroids in controlling acute asthma attacks in children who were treated in the emergency department: a controlled comparative study with oral prednisolone. J Allergy Clin Immunol 1998; 102:605–609. [PUBMED], [INFOTRIEVE], [CSA]
- Johnson M. Development of fluticasone propionate and comparison with other inhaled corticosteroids. J Allergy Clin Immunol 1998; 101:S434–S439. [PUBMED], [INFOTRIEVE], [CSA]
- Gern J E, Eggleston P A, Schubert K C, , et al. Peak flow variation in childhood asthma: a three-year analysis. J Allergy Clin Immunol 1994; 93:706–716. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Brand P L, Duiverman E J, Waalkens H J, van Essen-Zandvliet E E.M, Kerrebijn K, The Dutch CNSLD Study Group. Peak flow variation in childhood asthma: correlation with symptoms, airways obstruction, and hyperresponsiveness during long-term treatment with inhaled corticosteroids. Thorax 1999; 54:103–107. [PUBMED], [INFOTRIEVE]
- McIntyre H D, Mitchell C A, Bowler S D, Armstrong J A, Wooler J A, Cowley D M. Measuring the systemic effects of inhaled beclomethasone: timed morning urine collections compared with 24 hour specimens. Thorax 1995; 50:1280–1284. [PUBMED], [INFOTRIEVE]
- Price J, Lenney W, Duncan C, , et al. HPA-axis effects of nebulised fluticasone propionate compared with oral prednisolone in childhood asthma. Respir Med 2002; 96:625–631. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hoekstra M O, Grol M H, Bouman K, , et al. Fluticasone propionate in children with moderate asthma. Am J Respir Crit Care Med 1996; 154:1039–1044. [PUBMED], [INFOTRIEVE], [CSA]
- Lipworth B J. Systematic adverse effects of inhaled corticosteroid therapy: a systematic review and meta-analysis. Arch Intern Med 1999; 159:941–955. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pedersen S, Hansen O R. Budesonide treatment of moderate and severe asthma in children: a dose-response study. J Allergy Clin Immunol 1995; 95:29–33. [PUBMED], [INFOTRIEVE], [CSA]
- Shapiro G, Bronsky E A, LaForce C F, , et al. Dose-related efficacy of budesonide administered via a dry powder inhaled in the treatment of children with moderate to severe persistent asthma. J Pediatr 1998; 132:976–982. [PUBMED], [INFOTRIEVE]
- Gershman N H, Wong H H, Liu J T, Fahy J V. Low- and high-dose fluticasone propionate in asthma; effects during and after treatment. Eur Respir J 2000; 15:11–18. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Schuh S, Reisman J, Alshehri M, , et al. A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med 2000; 343:689–694. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Doull I J.M, Lampe F C, Smith S, Schreiber J, Freezer N J, Holgate S T. Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised, double-blind, placebo-controlled trial. BMJ 1997; 315:858–862. [PUBMED], [INFOTRIEVE]
- de Benedictis F M, Selvaggio D. Use of inhaler devices in pediatric asthma. Pediatr Drugs 2003; 5:629–638.