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Original Articles

A Rapid and Sensitive HPLC Method for the Determination of Venlafaxine and O‐Desmethylvenlafaxine in Human Plasma with UV Detection

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Pages 1297-1313 | Received 12 Nov 2002, Accepted 20 Dec 2002, Published online: 24 Jun 2011

References

  • Cherkaoui , S. , Rudaz , S. , Varesio , E. and Veuthey , J. L. 2001 . Online capillary electrophoresis–electrospary mass spectrometry for the stereoselective analysis of drugs and their metabolites . Electrophoresis , 22 ( 15 ) : 3308 – 3315 .
  • Cherkaoui , S. , Rudaz , S. and Veuthey , J. L. 2001 . Nonaqueous capillary electrophoresis–mass spectrometry for separation of venlafaxine and phase I metabolites . Electrophoresis , 22 ( 3 ) : 491 – 496 .
  • Desiderio , C. , Aturki , Z. and Fanali , S. 2001 . Use of vancomycin silica stationary phase in packed capillary electrochromatography. I. Enantiomer separation of basic compounds . Electrophoresis , 22 ( 3 ) : 535 – 543 .
  • Fanali , S. , Rudaz , S. , Veuthey , J. L. and Desiderio , C. 2001 . Use of vancomycin silica stationary phase in packed capillary electrochromatography. II. Enantiomer separation of venlafaxine and O‐desmethylvenlafaxine in human plasma . J. Chromatogr. A. , 919 ( 1 ) : 195 – 203 .
  • Fanali , S. , Catarcini , P. and Quaglia , M. G. 2002 . Use of vancomycin silica stationary phase in packed capillary electrochromatography. III. Enanatiomeric separation of basic compounds with the polar organic mobile phase . Electrophoresis , 23 ( 3 ) : 477 – 485 .
  • Rudaz , S. , Stella , C. , Balant‐Gorgia , E. , Fanali , S. and Veuthey , J. L. 2000 . Simultaneous stereoselective analysis of venlafaxine and O‐desmethylvenlafaxine enantiomers in clinical samples by capillary electrophoresis using charged cyclodextrins . J. Pharm. Biomed. Anal. , 23 ( 1 ) : 107 – 115 .
  • Rudaz , S. , Veuthey , J. L. , Desiderio , C. and Fanali , S. 1999 . Enantioseparation of venlafaxine and O‐desmethylvenlafaxine by capillary electrophoresis with mixed cyclodextrins . Chromatografia , 50 ( 5–6 ) : 369 – 372 .
  • Fanali , S. , Cotichini , V. and Porra , R. 1997 . Analysis of venlafaxine by capillary zone electrophoresis . J. Capillary Electrophor. , 4 ( 1 ) : 21 – 26 .
  • Labat , L. , Deveaux , M. , Dallet , P. and Dubost , J. P. 2002 . Separation of new antidepressants and their metabolites by micellar electrokinetic capillary chromatography . J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. , 773 ( 1 ) : 17 – 23 .
  • Vu , R. L. , Helmeste , D. , Albers , L. and Reist , C. 1997 . Rapid determination of venlafaxine and O‐desmethylvenlafaxine in human plasma by high‐performance liquid chromatography with fluorimetric detection . J. Chromatogr. B. , 703 ( 1–2 ) : 195 – 201 .
  • Li , H. D. , Ding , D. R. , Zhang , B. K. and Yuan , H. Y. 2001 . Studies on determination of the new drug venlafaxine in human plasma by HPLC with fluorimetric detection .
  • Clement , E. M. , Odontiadis , J. and Franklin , M. 1998 . Simultaneous measurement of venlafaxine and its major metabolite, oxydesmethylvenlafaxine, in human plasma by high‐performance liquid chromatography with coulometric detection and utilization of solid‐ phase extraction . J. Chromatogr. B. Biomed. Sci. Appl. , 705 ( 2 ) : 303 – 308 .
  • Matoga , M. , Pehourcq , F. , Titier , K. , Dumora , F. and Jarry , C. 2001 . Rapid high performance liquid chromatographic measurement of venlafaxine and O‐desmethylvenlafaxine in human plasma. Application to management of acute intoxication . J. Chromatogr. B. Biomed. Sci. Appl. , 760 ( 2 ) : 213 – 218 .
  • Tournel , G. , Houdret , N. , Hedouin , V. , Deveau , M. , Gosset , D. and Lhermitte , M. 2001 . High performance liquid chromatographic method to screen and quantitate seven selective serotonin reuptake inhibitors in human serum . J. Chromatogr. B. Biomed. Sci. Appl. , 761 ( 2 ) : 147 – 158 .
  • Hicks , D. R. , Wolaniuk , D. , Russell , A. , Cavanaugh , N. and Kraml , M. 1994 . High performance liquid chromatographic method for the simultaneous determination of venlafaxine and O‐desmethylvenlafaxine in biological fluids . Ther. Drug Monit. , 16 ( 1 ) : 100 – 107 .
  • Kelly , G. L. , Murray , L. and Sifton , D. W. , eds. 2002 . Physicians Desk Reference , 56th 3495 – 3504 . Montvale , NJ : Medical Economics Company, Inc. .

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