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Original Articles

Multicolumn Gradient Technique (“Walking Column”)

Pages 1093-1103 | Received 01 Nov 2003, Accepted 20 Nov 2003, Published online: 22 Aug 2007

References

  • Schoenmakers , P. 1998 . “ Programmed analysis ” . In Handbook of HPLC Edited by: Katz , E. , Eksteen , R. , Schoenmakers , P. and Miller , N. 193 – 231 . New York : Marcel Dekker, Inc. .
  • Snyder , L. R. and Kirkland , J. J. 1979 . “ Column switching and stationary phase programming ” . In Introduction to Modern Liquid Chromatography 694 – 719 . New York : John Wiley & Sons .
  • Neue , U. D. 1997 . “ Special technique ” . In HPLC Columns, Theory, Technology and Practice 263 New York : Wiley‐VCH .
  • Hogendoorn , E. A. and Van Zoonen , P. 1995 . Coupled-column reversed-phase liquid chromatography in environmental analysis . J. Chromatogr. , 703 : 151
  • Ramsteiner , K. A. 1988 . Systematic approach to column switching . J. Chromatogr. , 456 : 3 – 20 . [CROSSREF]
  • Letter , S. W. 1997 . Automated column-selection and switching systems for HPLC . LC‐GC Intl. , 10 : 798 – 802 .
  • Needham , S. R. 2000 . Fast, efficient separations in drug discovery—LC-MS analysis using column switching and rapid gradients . LC‐GC , 18 : 1158
  • Seidel‐Morgenstern , A. and Guiochon , G. 1993 . Theoretical study of recycling in preparative chromatography . A.I.Ch.E.J. , 39 : 809 – 819 .
  • Farjam , A. , DeJong , G. J. , Frei , R. W. , Brinkman , U. A.Th. , Haasnoot , W. , Hamers , A. R. , Schilt , R. and Huf , F. A. 1988 . Immunoaffinity pre-column for selective on-line sample pretreatment in high-performance liquid chromatography determination . J. Chromatogr. , 452 : 419 – 433 . [PUBMED] [INFOTRIEVE] [CROSSREF]
  • Kirn , K. H. , Kirn , H. J. , Kim , J.‐H. and Shin , S. D. 2001 . Determination of terbutaline enantiomers in human urine by coupled achiral-chiral high-performance liquid chromatography with fluorescence detection . J. Chromatogr. B , 751 : 69 – 77 . [CSA]
  • Davis , M. T. , Beierle , J. , Bures , E. T. , McGinley , M. D. , Mort , J. , Robinson , J. H. , Chris , S. , Yu , W. , Luethy , R. and Patterson , S. D. 2001 . Automated LC-LC-MS-MS platform using binary ion-exchange and gradient reversed-phase chromatography for improved proteomic analyses . J. Chromatogr. B , 752 : 281 – 291 . [CSA]
  • Schafer , Ch. and Lubda , D. 2001 . Alkyi diol silica: restricted access pre-column packing for fast liquid chromatography—integrated sample preparation of biological fluids . J. Chromatogr. , 909 : 73 – 78 . [CROSSREF]

Suggested Additional Reading

  • Hogendoorn , E. A. and van Zoonen , P. 1995 . Coupled-column reversed-phase liquid chromatography in environmental analysis . J. Chromatogr. , 703 : 149 – 166 . [CROSSREF]
  • Koenigbauer , M. J. and Majors , R. E. 1990 . Sample cleanup in high performance liquid chromatography using on-line multidimensional techniques . LC‐GC , 3 : 10 – 16 .
  • Little , C. J. , Tompkins , D. J. , Stahel , O. , Frei , R. W. and Werkhoven‐Goewie , C. E. 1983 . Applications of a microprocessor-controlled valve-switching unit for automated sample cleanup and trace enrichment in high-performance liquid chromatography . J. Chromatogr. , 264 : 183 – 196 . [CROSSREF]
  • Lukulay , P. H. and McGuffin , V. L. 1995 . Solvent modulation in liquid chromatography. Extension to serially coupled columns . J. Chromatogr. , 691 : 171 – 185 . [CROSSREF]
  • Gort , S. M. , Hogendoorn , E. A. , Dijkman , E. , van Zoonen , P. and Hoogerbrugge , R. 1996 . The optimization of step-gradient elution conditions in liquid chromatography: application to pesticide residue analysis using coupled-column reversed-phase LC . Chromatographia , 42 : 17 – 24 .
  • Hennion , M. C. 1999 . Solid-phase extraction: method development, sorbents, and coupling with liquid chromatography . J. Chromatogr. , 856 : 3 – 54 . [CROSSREF]
  • Fried , K. and Wainer , I. W. 1997 . Column-switching techniques in the biomedical analysis of stereoisomeric drugs: why, how and when . J. Chromatogr. B , 689 : 91 – 104 . [CSA]

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