Simultaneous HPLC Assay of Lenampicillin (Ampicillin Prodrug), Ampicillin, and Marker Compound for High‐Throughput in Vitro Assessment of Intestinal Absorption and Metabolism Using Caco‐2 Cells

Dr. Takashi Mizuma Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, JapanCorrespondence[email protected]

Sayaka Sakaguchi Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan

Masahiro Hayashi Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan

References

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Mizuma , T. , Narasaka , T. and Awazu , S. 2002 . Uptake of cyclic dipeptide by PEPT1 in Caco‐2 cells: phenolic hydroxyl group of substrate enhances affinity for PEPT1 . J. Pharm. Pharmacol. , 54 : 1293
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Mizuma , T. , Momota , R. , Haga , M. and Hayashi , M. 2004 . Factors affecting glucuronidation activity in Caco‐2 cells . Drug Metab. Pharmacokinet. , 19 : 130
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Simultaneous HPLC Assay of Lenampicillin (Ampicillin Prodrug), Ampicillin, and Marker Compound for High‐Throughput in Vitro Assessment of Intestinal Absorption and Metabolism Using Caco‐2 Cells

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Simultaneous HPLC Assay of Lenampicillin (Ampicillin Prodrug), Ampicillin, and Marker Compound for High‐Throughput in Vitro Assessment of Intestinal Absorption and Metabolism Using Caco‐2 Cells

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