Carcinogen-Metabolizing Enzymes and Insecticides

References

• Selim , M.I. and El-Sebae , A.H. 1995 . Pesticides regulation in Egypt . Bull. High Inst. Pub. health , 25 : 77 – 94 .
   Google Scholar
• El-Sebae , A.H. 1990 . “ Fate and undesirable effects of pesticides in Egypt ” . In Toxicology and Climate Edited by: Bourdeau , P. , Hains , J.A. , Klein , W. and Krishna , C.R. 349 – 371 . New York : John Wiley and Sons Ltd .
   Google Scholar
• Falandysz , J. 2003 . The use amount of chlordane, heptachlor and heptachlor epoxide in Poland . Rocz Panstw Zakl Hig. , 54 ( 1 ) : 49 – 64 .
   Google Scholar
• EL-Sebae , A.H. , Soliman , S.A. , Abou-El-Amayem , M. and Ahmed , N.S. 1977 . Neurotoxicity of the organophosphorus insecticides leptophos and EPN . J. Environ. Sci. Health, Part B , 12 : 269 – 288 .
   Google Scholar
• Appleyard , W.T. , Williams , J.T. and Davie , R. 1984 . Evaluation of three synthetic pyrethroids in the control of sheep headfly disease . Vet. Rec. , 114 : 214 – 215 .
   Google Scholar
• Shakoori , A.R. , Ali , S.S. and Saleem , M.A. 1988 . Effects of six months’ feeding of cypermethrin on the blood and liver of albino rats . J. Biochem. Toxicol. , 11 : 59 – 71 .
   Google Scholar
• Abou Zeid , M.M. , El-Barouty , G. , Abdel-Reheim , E. , Blancato , J. , Dary , C. , El-Sebae , A.H. and Saleh , M.A. 1993 . Malathion disposition in dermally and orally treated rats and its impact on the blood serum acetylcholine esterase and protein profile . J. Environ. Sci. Health, Part B , 28 : 413 – 430 .
   Google Scholar
• Harris , C.C. , Vahakangas , K. , Newman , M.J. , Trivers , G.E. , Shamsuddin , A. , Sinopoli , N.T. , Mann , D.L. and Wright , W.E. 1985 . Detection of benzo(a)pyrene diolepoxide in serum from coke oven workers . Proc. Natl. Acad. Sci. USA , 82 : 6672 – 6676 .
   Google Scholar
• Savela , K. and Hemminki , K. 1991 . DNA adducts in lymphocytes and granulocytes of smokers and nonsmokers detected by the 32P-postlabeling assay . Carcinogenesis , 12 : 503 – 508 .
   Google Scholar
• Conney , A.H. 1982 . Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons . GHA Clowes Memorial Lecture. Cancer Res. , 42 : 4875 – 4917 .
   Google Scholar
• Ashurst , S. and Cohen , G.L. 1981 . The formation and persistence of benzo(a)pyrene metabolite-deoxyribonucleoside adducts in rat skin in vivo . Int. J. Cancer , 28 : 387 – 392 .
   Google Scholar
• Gonzalez , F.J. and Gelboin , H.V. 1994 . Role of human cytochrome P-450 in the metabolic activation of chemical carcinogens and toxins . Drug Metab. Rev. , 26 : 165 – 171 .
   Google Scholar
• Lake , B.G. 1999 . Coumarin metabolism, toxicity and carcinogenicity: relevance for human risk assessment . Food Chem. Toxicol. , 37 : 423 – 453 .
   Google Scholar
• Gooderham , N.J. and Mannering , G.J. 1985 . Depression of the hepatic cytochrome P450 monooxygenase system by treatment of mice with the anti-neoplastic agent, 5-azacytidine . Cancer Res. , 45 : 1569 – 1572 .
   Google Scholar
• Lijinsky , W. , Conrad , E. and Van De Bogart , R. 1972 . Nitrosoamines formed by drug/nitrite interactions . Nature , 239 : 165 – 174 .
   Google Scholar
• Preussmann , P. 1984 . “ Occurrence and exposure to N-nitroso compounds and precursors ” . In N-nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer Edited by: LO’Neil , I.K. , Von Borstll , R.C. , Miller , C.T. , Long , J. and Bartsch , H. Vol. 57 , 3 – 15 . Lyon , , France : IARC Sci. Publ. .
   Google Scholar
• Bartsch , H. and Montesano , R. 1984 . Relevance of nitrosamines to human cancer . Carcinogenesis , 5 : 1381 – 1393 .
   Google Scholar
• Hill , M.J. 1988 . “ N-nitroso compounds and human cancer ” . In Nitrosamine Toxicology and Microbiology Edited by: Hill , M.J. 90 – 102 . Chichester, Ellis , Horwood
   Google Scholar
• Arcos , J. , Davies , D.L. , Brown , C. and Argus , E. 1977 . Repressible and inducible enzymatic forms of DMN-demethylase . Z. Krebsforsch , 89 : 181 – 199 .
   Google Scholar
• Mostafa , M.H. and Sheweita , S.A. 1992 . Modification of the oxidative N-demethylation of dimethylnitrosamine by various anti-inflammatory drugs . Ramazzini Newsletter , 2 : 15 – 22 .
   Google Scholar
• Yoo , J.S.H. , Guengerich , F.P. and Yang , C.S. 1988 . Metabolism of N-nitrosodialkylamines by human liver microsomes . Cancer Res. , 88 : 1499 – 1504 .
   Google Scholar
• Camus , A.M. , Geneste , O. , Honkakoski , P. , Bereziat , J.C. , Henderson , C.J. , Wolf , C.R. , Bartsch , H. and Lang , M.A. 1993 . High variability of metabolism among individuals: role of cytochrome P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans . Mol. Carcinogenesis , 7 : 268 – 275 .
   Google Scholar
• Umbenhauer , D. , Wild , C.P. , Montesano , R. , Saffhill , R. , Boyle , J.M. , Huh , N. , Kirstein , U. , Thomale , J. , Rajewski , M.F. and Lu , S.H. 1985 . O 6-Methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer . Int. J. Cancer , 36 : 661 – 665 .
   Google Scholar
• Cooper , D.P. , Yoa , G.F. , Qu , Y.H. and O’Connor , P.J. 1991 . DNA methylation in individuals at high risk for stomach cancer . Br. J. Cancer , 13 : 65 – 71 .
   Google Scholar
• Sheweita , S.A. 1999 . Changes in the activity of mixed-function oxidase enzymes in the liver of male mice: influence of heavy metals . Envir. Nutr. Inter. , 3 : 123 – 135 .
   Google Scholar
• Sheweita , S.A. , Abu El-Maati , M.R. , El-Shahat , F.G. and Bazeed , M.A. 2001 . Changes in the expression of cytochrome P450 2E1 and the activity of carcinogen-metabolizing enzymes in Schistosoma haematobium-infected human bladder tissues . Toxicol. , 162 : 43 – 52 .
   Google Scholar
• Omura , J. and Sato , R. 1964 . The carbon monoxide binding pigment of liver microsomes. I . Evidence for its hemoprotein nature. J. Biol. Chem. , 239 : 2370 – 2378 .
   Google Scholar
• Wiebel , F.J. and Gelboin , H.V. 1975 . Aryl hydrocarbon (benzo [a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status . Distinction of two types by 7,8-benzoflavone. Bioch. Pharmacol. , 24 : 1511 – 1515 .
   Google Scholar
• Venkatesan , N. , Arcos , J.C. and Argus , M.F. 1968 . Differential effect of effect of polycyclic hydrocarbons on the demethylation of the carcinogen dimethylnitrosamine by rat tissues . Life Sci. , 7 : 111 – 119 .
   Google Scholar
• Nash , T. 1953 . The colorimetric estimation of formaldehyde by means of Hantzsch reactions . Biochem. J. , 55 : 416 – 421 .
   Google Scholar
• Mclean , A.E. and Day , P.A. 1974 . The use of new methods to measure: the effect of diet and inducers of microsomal enzymes synthesis on cytochrome P-450 in liver homogenates, and on metabolism of dimethylnitrosamine . Biochem. Pharmacol. , 23 : 1173 – 1180 .
   Google Scholar
• Habig , W. , Pabst , M. and Jakoby , W. 1974 . Glutathione S-transferases. The first enzymatic step in mercapturic acid formation . J. Biol. Chem. , 249 : 7130 – 7139 .
   Google Scholar
• Mitchell , J.R. , Jollow , D.J. , Potter , W.Z. , Davis , D.C. , Gillette , J.R. and Brodi , B.B. 1973 . Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism . J. Pharmacol. Exper. Therap. , 187 : 185 – 194 .
   Google Scholar
• James , N.S. , Gay , R.J. and Hilf , R. 1980 . Influence of estrogen on glutathione levels and glutathione-metabolizing enzymes in uteriand R3230 AC mammary tumors of rats . Biochem. Biophys. Acta , 630 : 485 – 496 .
   Google Scholar
• Lowry , O.H. , Rosbrough , N.J. , Farr , A.L. and Randall , R.J. 1951 . Protein measurement with the Folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 .
   Google Scholar
• Yang , C.S. , Yoo , J.S. , Ishizaki , H. and Hong , J.Y. 1990 . Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation . Drug Metab. Rev. , 22 : 147 – 159 .
   Google Scholar
• Oropeza-Hernandez , L.F. , Sierra-Santoyo , A. , Cebrian , M.E. , Manno , M. and Albores , A. 1995 . Differences in hepatic drug metabolizing enzymes and their response to lindane in rat, rabbit and monkey . Pharmacol. Toxicol. , 77 ( 2 ) : 136 – 141 .
   Google Scholar
• Parmar , D. , Yadav , S. , Dayal , M. , Johri , A. , Dhawan , A. and Seth , P.K. 2003 . Effect of lindane on hepatic and brain cytochrome P450s and influence of P450 modulation in lindane induced neurotoxicity . Food Chem. Toxicol. , 41 ( 8 ) : 1077 – 1087 .
   Google Scholar
• Sheweita , S.A. 2000 . Drug-metabolizing enzymes: mechanisms and functions . Current Drug Metab. , 1 ( 2 ) : 107 – 132 .
   Google Scholar
• Vodela , J.K. and Dalvi , R.R. 1995 . Comparative toxicological studies of chlorpyrifos in rats and chickens . Vet. Hum. Toxicol. , 37 : 1 – 3 .
   Google Scholar
• Poland , A. , Glover , E. and Kende , A.S. 1976 . Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol . Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. J. Biol. Chem. , 251 : 4936 – 4946 .
   Google Scholar
• Pohjanvirta , R. , Viluksela , M. , Tuomisto , J.T. , Unkila , M. , Karasinska , J. , Franc , M.A. , Holowenko , M. , Giannone , J.V. , Harper , P.A. , Tuomisto , J. and Okey , A.B. 1999 . Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains . Toxicol. Appl. Pharmacol. , 155 ( 1 ) : 82 – 95 .
   Google Scholar
• Iscan , M. , Coban , T. , Cok , I. , Bulbul , D. , Eke , B.C. and Burgaz , S. 2003 . The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association? . Breast Cancer Res. Treat. , 72 ( 2 ) : 173 – 182 .
   Google Scholar
• Alawi , M.A. , Tamimi , S. and Jaghabir , M. 1999 . Storage of organochlorine pesticides in human adipose tissues of Jordanian males and females . Chemosphere , 38 ( 12 ) : 2865 – 2873 .
   Google Scholar
• Hansen , M.E. and Matsumura , F. 2001 . Down-regulation of particulate protein kinase cepsilon and up-regulation of nuclear activator protein-1 DNA binding in liver following in vivo exposure of B6C3F1 mice to heptachlor epoxide . J. Biochem. Mol. Toxicol. , 15 ( 1 ) : 1 – 14 .
   Google Scholar
• Sato , K. 1989 . Glutathione transferase as markers of preneoplasia and neoplasia . Adv. Cancer Res. , 52 : 205 – 255 .
   Google Scholar
• Sexton , D.J. and Mutus , B. 1992 . Glutathione reductase from a variety of sources are inhibited by physiological levels of glutathione . Comp. Biochem. Physiol. , 103B : 897 – 901 .
   Google Scholar
• Seelig , G.F. and Meister , A. 1985 . Glutathione biosynthesis, γ-glutamyl cycteine synthetase from rate kidney . Meth. Enzymol. , 113 : 379 – 390 .
   Google Scholar