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Nucleosides, Nucleotides & Nucleic Acids Volume 20, 2001 - Issue 4-7
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Original Articles

SYNTHESIS AND ANTIVIRAL ACTIVITY OF METHYLENEDIFLUOROCYCLOPROPANE ANALOGUES OF NUCLEOSIDES

R. Wang Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, 48201-1379, U.S.A.
,
M. B. Ksebati Central Instrumentation Facility, Department of Chemistry, Wayne State University, Detroit, Michigan, 48202, U.S.A.
,
J. C. Drach Department of Biologic and Materials Science, School of Dentistry, University of Michigan, Ann Arbor, Michigan, 48019-1078, U.S.A.
&
J. Zemlicka Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, 48201-1379, U.S.A.
Pages 329-332 | Published online: 07 Feb 2007

REFERENCES

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  • Welch , J. T. and Eswarakrishnan , S. 1991 . Fluorine in Bioorganic Chemistry 220 – 2333 . New York : John Wiley & Sons .
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  • The E/Z nomenclature was used previously1 to describe cis (Z) and trans (E) isomers 1 and 2. Following the E/Z rules, the cis-isomers 8a, 8b are of the E- and trans-isomers 9a, 9b of Z-configuration (see also18, reference 31)
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  • Qiu , Y.-L. and Zemlicka , J. 1999 . Nucleosides & Nucleotides , 18 : 2285 – 2300 .

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