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Original Articles

PRACTICAL SYNTHESIS, SEPARATION, AND STEREOCHEMICAL ASSIGNMENT OF THE PMPA PRO-DRUG GS-7340

, , , , , & show all
Pages 621-628 | Published online: 07 Feb 2007

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  • Chapman , H. , Kernan , M. , Rohloff , J. , Sparacino , M. and Terhorst , T. September, 2000 . “ Purification of PMPA Amidate Prodrugs by SMB Chromatography and X-Ray Crystallography of the Diastereomerically Pure GS-7340 ” . In Submitted for publication in a supplement to Nucleosides and Nucleotides on the XIV International Roundtable: Nucleosides , Nucleotides and their Biological Applications San Francisco, CA
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  • Chiral Technologies Inc., amylose-tris(alpha-methyl benzyl carbamate) coated on silica gel
  • Continuous simulated moving bed chromatography was performed by Aerojet Fine Chemicals Rancho Cordova, CA
  • Single-crystal x-ray structure determination was performed by F. J. Hollander at University of California Berkeley

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