REFERENCES
- Nielsen , P. E. 1999 . Acc. Chem. Res. , 32 : 624 – 630 .
- Egholm , M. , Christensen , L. , Dueholm , L. D. , Buchardt , O. , Coull , J. and Nielsen , P. E. 1995 . Nucleic Acids Res. , 23 : 217 – 222 .
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- Characteristic signals: 2: 1H NMR (CDCl3) δ: 10.1 (s, 1H, G-NH), 7.9 (s, 1H, G-H8). 13C NMR δ: 167.2 (G-CH2-CO), 162.9 (G-C2), 156.4 (G-C4), 148.0 (G-C6), 145.2 (G-C8), 112.2 (G-C5). 6b: 1H NMR (CDCl3) δ: 12.1 (br s, 1H, G-NH), 8.4 (s, 1H, G-H8), 5.6 (m, 1H, H4). 13C NMR δ: 156.4 (G-C2), 156.0 (G-C4), 147.5 (G-C6), 142.3 (G-C8), 111.5 (G-C5), 59.5 (C4). MALDI-TOF: PNA 8: [M]obs = 4499.75, [M]calc = 4495.64; PNA 9: [M]obs = 4580.88, [M]calc = 4575.69
- Nielsen , P. E. and Egholm , M. , eds. 1999 . Peptide Nucleic Acids: Protocols and Applications Norfolk, , UK : Horizon Scientific Press .