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Nucleosides, Nucleotides & Nucleic Acids Volume 20, 2001 - Issue 4-7
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Original Articles

CONSTRAINED FLEXIBILITY IN PNA: DNA BINDING STUDIES WITH BRIDGED AMINOPROPYLGLYCYL PNA

P. S. Lonkar Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411 008, India
,
V. A. Kumar Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411 008, India
&
K. N. Ganesh Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411 008, India
Pages 1197-1200 | Published online: 07 Feb 2007

REFERENCES

  • Nielsen , P. E. , Egholm , M. , Berg , R. H. and Buchardt , O. 1991 . Science , 254 : 1497 – 1500 .
  • Uhlmann , E. , Peyman , A and Will , W. 1998 . Angew. Chem. Int. Ed. , 37 : 2796 – 2893 .
  • Sforza , S. , Corradini , R. , Ghirardi , S. , Dossena , A. and Marchelli , R. 2000 . Eur. J. Org. Chem. , : 2905 – 2913 .
  • Gangamani , B. P. , Kumar , V. A. and Ganesh , K. N. 1996 . Tetrahedron , 52 : 15017 – 15030 .
  • Gangamani , B. P. , Kumar , V. A. and Ganesh , K. N. 1999 . Tetrahedron , 55 : 177 – 192 .
  • Hyrup , B. , Egholm , M. , Rolland , M. , Nielsen , P. E. , Berg , R. H. and Buchardt , O. 1993 . J. Chem. Soc. Chem. Commun. , : 518
  • Bousquet , Y. , Anderson , P. C. , Bogri , T. , Duceppe , J.-S. , Grenier , L. and Guse , I. 1997 . Tetrahedron , 53 : 15671 – 15680 .
  • 1H NMR (CDCl3) δ: 7.3 (s, 1H), 7.0 (s, 1H), 5.4 (m, 1H), 5.0 (m, 1H), 4.7 (m, 1H), 4.3 (m, 1H), 3.8 (s, 3H), 3.5 (m, 2H), 2.6 (m, 1H), 2.1 (m, 1H), 2.0 (s, 3H), 1.5 (s, 9H). [M]calc. = 410, [M]obs. = 411
  • Nielsen , P. E. and Egholm , M. , eds. 1999 . Peptide Nucleic Acids: Protocols and Applications Norfolk, , UK : Horizon Scientific Press .

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