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Original Articles

SYNTHESIS OF 5-ETHYNYL-2′-DEOXYURIDINE-5′-BORANOMONO PHOSPHATE AS A POTENTIAL THYMIDYLATE SYNTHASE INHIBITOR

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Pages 1047-1049 | Received 15 Oct 2004, Accepted 19 Jan 2005, Published online: 15 Nov 2011

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  • Dobrikov , M. , Sergueeva , Z. A. and Shaw , B. R. 2003 . Incorporation of (α-P-borano)-2′,3′-dideoxycytidine-5-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase . Nucleosides Nucleotides Nucleic Acids , 22 : 1651 – 1655 .
  • Selmi , B. , Boretto , B. , Sarfati , S. R. , Guerreiro , C. and Canard , B. 2001 . Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an α-boranophosphate nucleoside analogue . J. Biol. Chem. , 276 : 48466 – 48472 .
  • Wang , X. , Dobrikov , M. , Sergueeva , D. and Shaw , B. R. 2003 . RNase H activation by stereoregular boranophosphate oligonucleotide . Nucleosides Nucleotides Nucleic Acids , 22 : 1151 – 1153 .

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