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Nucleosides, Nucleotides & Nucleic Acids Volume 24, 2005 - Issue 5-7
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Original Articles

SYNTHESIS AND BIOCHEMICAL PROPERTIES OF NOVEL mRNA 5′ CAP ANALOGS RESISTANT TO ENZYMATIC HYDROLYSIS

Marcin Kalek Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Jacek Jemielity Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Ewa Grudzien Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Joanna Zuberek Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Elzbieta Bojarska Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Lean S. Cohen Department of Biology, CUNY Graduate Center, New York, USA
,
Janusz Stepinski Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Ryszard Stolarski Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
,
Richard E. Davis Department of Pediatrics and Biochemistry and Molecular Biology, University of Colorado School of Medicine, Aurora, Colorado, USA
,
Robert E. Rhoads Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
&
Edward Darzynkiewicz Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warsaw, Poland
 show all
Pages 615-621 | Published online: 15 Nov 2011

REFERENCES

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  • Canaani , D. , Revel , M. and Groner , Y. 1976 . Translational discrimination of “capped” and “non-capped” mRNAS: inhibition by series of chemical analogs of m7GpppX . FEBS Lett. , 64 : 326 – 331 .
  • Jemielity , J. , Fowler , T. , Zuberek , J. , Stepinski , J. , Lewdorowicz , M. , Niedzwiecka , A. , Stolarski , R. , Darzynkiewicz , E. and Rhoads , R. E. 2003 . Novel “anti-reverse” cap analogs with superior translational properties . RNA , 9 : 1108 – 1022 .
  • Liu , H. , Rodgers , N. D. , Jiao , X. and Kiledjian , M. 2002 . The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases . EMBO J. , 21 : 4699 – 4708 .

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