COMBINATION OF POLY(L-LYSINE)-GRAFT-DEXTRAN COPOLYMER AND 2′-O,4′-C-METHYLENE BRIDGED NUCLEIC ACID (2′,4′-BNA) MODIFICATION SYNERGISTICALLY STABILIZES PYRIMIDINE MOTIF TRIPLEX AT NEUTRAL PH

Hidetaka Torigoe Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, Tokyo, Japan

Takuma Katayama Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, Tokyo, Japan

Satoshi Obika Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

Atushi Maruyama Institute for Materials Chemistry and Engineering, Kyushu University, Fukuoka, Japan; PRESTO, Japan Science and Technology Agency, Kawaguchi, Japan

Takeshi Imanishi Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

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COMBINATION OF POLY(L-LYSINE)-GRAFT-DEXTRAN COPOLYMER AND 2′-O,4′-C-METHYLENE BRIDGED NUCLEIC ACID (2′,4′-BNA) MODIFICATION SYNERGISTICALLY STABILIZES PYRIMIDINE MOTIF TRIPLEX AT NEUTRAL PH

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COMBINATION OF POLY(L-LYSINE)-GRAFT-DEXTRAN COPOLYMER AND 2′-O,4′-C-METHYLENE BRIDGED NUCLEIC ACID (2′,4′-BNA) MODIFICATION SYNERGISTICALLY STABILIZES PYRIMIDINE MOTIF TRIPLEX AT NEUTRAL PH

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