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Original Articles

STRUCTURAL STUDIES ON LNA QUADRUPLEXES

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Pages 795-800 | Published online: 15 Nov 2011

REFERENCES

  • Henderson , E. , Hardin , C. C. , Walk , S. K. , Tinoco , I. Jr. and Blackburn , E. H. 1987 . Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs . Cell , 51 : 899 – 908 .
  • Macaya , R. F. , Schultze , P. , Smith , F. W. , Roe , J. A. and Feigon , J. 1993 . Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution . Proc. Natl. Acad. Sci. U. S. A. , 334 : 3745 – 3749 .
  • Wang , Y. and Patel , D. J. 1995 . Solution structure of the Oxytricha telomeric repeat d[G4(T4G4)3] G-tetraplex . J. Mol. Biol. , 251 : 76 – 94 .
  • Schultze , P. , Flint , W. S. and Feigon , J. 1994 . Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG) . Structure , 2 : 221 – 233 .
  • Smith , F. W. and Feigon , J. 1992 . Quadruplex structure of Oxytricha telomeric DNA oligonucleotides . Nature , 356 : 164 – 168 .
  • Aboul-ela , F. , Murchie , A. I.H. , Norman , D. G. and Lilley , D. M.J. 1994 . NMR study of a parallel-stranded tetraplex formation by the hexadeoxynucleotide d(TG4T) . J. Mol. Biol. , 243 : 458 – 471 .
  • Patel , P. K. , Koti , A. S.R. and Hosur , R. V. 1999 . NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad . Nucleic Acids Res. , 27 : 3836
  • Sen , D. and Gilbert , W. 1988 . Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis . Nature , 334 : 364 – 366 .
  • Sen , D. and Gilbert , W. 1990 . A sodium-potassium switch in the formation of four-stranded G4-DNA . Nature , 334 : 410 – 414 .
  • Sen , D. and Gilbert , W. 1992 . Novel DNA superstructures formed by telomere-like oligomers . Biochemistry , 31 : 65 – 70 .
  • Laughlan , G. , Murchie , A. I. , Norman , D. G. , Moore , M. H. , Moody , P. C.E. , Lilley , D. M.J. and Luisi , B. 1994 . The highresolution crystal structure of a parallel-stranded guanine tetraplex . Science , 265 : 520 – 524 .
  • Phillips , K. , Dauter , Z. , Murchie , A. I. , Lilley , D. M.J. and Luisi , B. 1997 . The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution . J. Mol. Biol. , 273 : 171 – 182 .
  • Wang , Y. and Patel , D. J. 1993 . Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex . Structure , 1 : 263 – 282 .
  • Catasti , P. , Chen , X. , Moyzis , R. K. , Bradbury , E. M. and Gupta , G. 1996 . Structure-function correlations of the insulin-linked polymorphic region . J. Mol. Biol. , 264 : 534 – 545 .
  • Kang , C. , Zhang , X. , Ratliff , R. , Moyzis , R. and Rich , A. 1992 . Crystal structure of four-stranded Oxytricha telomeric DNA . Nature , 356 : 126 – 131 .
  • Schultze , P. , Macaya , R. F. and Feigon , J. 1994 . Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG) . J. Mol. Biol. , 235 : 1532 – 1547 .
  • Henderson , E. R. and Blackburn , E. H. 1989 . An overhanging 3′ terminus is a conserved feature of telomeres . Mol. Cell. Biol. , 9 : 345 – 348 .
  • Blackburn , E. H. 1991 . Structure and function of telomeres . Nature , 350 : 569 – 573 .
  • Nikaido , T. , Yamawaki-Kataoka , Y. and Honjo , T. 1982 . Nucleotide sequences of switch regions of immunoglobulin C epsilon and C gamma genes and their comparison . J. Biol. Chem. , 257 : 7322 – 7329 .
  • Jeffreys , A. J. , Wilson , V. and Thein , S. L. 1985 . Hypervariable ″minisatellite″ regions in human DNA . Nature , 314 : 67 – 73 .
  • Collier , D. A. , Griffin , J. A. and Wells , R. D. 1988 . Non-B right-handed DNA conformations of homopurine.homopyr- imidine sequences in the murine immunoglobulin C alpha switch region . J. Biol. Chem. , 263 : 7397 – 7405 .
  • Hastie , N. D. and Allshire , R. C. 1989 . Human telomeres: fusion and interstitial sites . Trends Genet. , 5 : 326 – 331 .
  • Akman , S. A. , Lingeman , R. G. , Doroshow , J. H. and Smith , S. S. 1991 . Quadruplex DNA formation in a region of the tRNA gene supF associated with hydrogen peroxide mediated mutations . Biochemistry , 30 : 8648 – 8653 .
  • Nickol , J. M. and Felsenfeld , G. 1983 . DNA conformation at the 5′ end of the chicken adult beta-globin gene . Cell , 35 : 467 – 477 .
  • Simonsson , T. , Pecinka , P. and Kubista , M. 1998 . DNA tetraplex formation in the control region of c-myc . Nucleic Acids Res. , 26 : 1167 – 1172 .
  • Hammond-Kosack , M. C. , Kilpatrick , M. W. and Docherty , K. 1992 . Analysis of DNA structure in the human insulin gene-linked polymorphic region in vivo . J. Mol. Endocrinol. , 9 : 221 – 225 .
  • Wengel , J. 1998 . Synthesis of 3′-C- and 4′-C-branched oligonucleotides and the development of locked nucleic acid (LNA) . Acc. Chem. Res. , 32 : 301 – 310 .
  • Singh , S. K. , Nielsen , P. , Koshkin , A. A. and Wengel , J. 1998 . LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition . Chem. Commun. , 4 : 455 – 456 .
  • Koller , E. , Gaarde , W. A. and Monia , B. P. 2000 . Elucidating cell signaling mechanisms using antisense technology . Trends Pharmacol. Sci. , 21 : 142 – 148 .
  • Braasch , D. A. and Corey , D. R. 2002 . Novel antisense and peptide nucleic acid strategies for controlling gene expression . Biochemistry , 41 : 4503 – 4510 .
  • Opalinska , J. B. and Gewirtz , A. M. 2002 . Nucleic-acid therapeutics: basic principles and recent applications . Nat. Rev., Drug Discov. , 1 : 503 – 514 .
  • Randazzo , A. , Esposito , V. , Ohlenschlaeger , O. , Ramachandran , R. and Mayol , L. 2004 . NMR solution structure of a parallel LNA quadruplex . Nucleic Acids Res. , 32 ( 10 ) : 3083 – 3092 .
  • Bock , L. C. , Griffin , L. C. , Latham , J. A. , Vermaas , E. H. and Toole , J. J. 1992 . Selection of single-stranded DANN molecules that bind and inhibit human thrombin . Nature , 355 : 564 – 566 .
  • Dapic , V. , Abdomerovic , V. , Marrington , R. , Peberdy , J. , Rodger , A. , Trent , J. O. and Bates , P. J. 2003 . Biophysical and biological properties of quadruplex oligodeoxyribonucleotides . Nucleic Acids Res. , 31 : 2097 – 2107 .
  • Jing , N. , Xiong , W. , Guan , Y. , Pallansch , L. and Wang , S. 2002 . Potassium-dependent folding: a key to intracellular delivery of G-quartet oligonucleotides as HIV inhibitors . Biochemistry , 41 ( 17 ) : 5397 – 5403 .

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