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Original Articles

CONTROL OF DNA CONFORMATION USING 3′-S-PHOSPHOROTHIOLATE-MODIFIED LINKAGES

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Pages 491-495 | Published online: 15 Nov 2011

REFERENCES

  • Beevers , A. P.G. , Fettes , K. J. , O'Neil , I. A. , Roberts , S. M. , Arnold , J. R.P. , Cosstick , R. and Fisher , J. 2002 . Probing the effect of a 3′-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design . Chem. Commun. , : 1458 – 1459 .
  • Beevers , A. P.G. , Witch , E. M. , Jones , B. C.N.M. , Cosstick , R. and Fisher , J. 1999 . Conformational analysis of 3′-S-PO3-linked ribo- and deoxyribodinucleoside monophosphates . Magn. Reson. Chem. , 37 : 814 – 820 .
  • Beevers , A. P.G. , Fettes , K. J. , Sabbagh , G. , Murad , F. K. , Arnold , J. R.P. , Cosstick , R. and Fisher , J. 2004 . NMR and UV studies of 3′-S-phosphorothiolate modified DNA in a DNA:RNA hybrid dodecamer duplex; implications for antisense drug design . Org. Biomol. Chem. , 2 : 114 – 119 .
  • Peterson , M. and Wengel , J. 2003 . LNA: a versatile tool for therapeutics and genomics . Trends Biotechnol. , 21 ( 2 ) : 74 – 81 .
  • Sabbagh , G. , Fettes , K. J. , Gosian , R. , O'Neil , I. A. and Cosstick , R. 2004 . Synthesis of phosphorothioamidites derived from 3′-thio-3′-deoxythymidine and 3′-thio-3-deoxycytidine and the automated synthesis of oligodeoxynucleo-tides containing a 3′-S-phosphorothiolate linkage . Nucleic Acids Res. , 32 ( 2 ) : 495 – 501 .

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