Preparation and Release Characteristics of Protein-Loaded Polyanion/Gelatin Complex

REFERENCES

• Langer R. New Methods of Drug Delivery. Science 1990; 249: 1527–1533
   PubMed Web of Science ®Google Scholar
• Cleland J. C. Single-Administration Vaccines: Controlled Release Technology to Mimic Repeated Immunization. TIBTECH 1999; 17: 25–29
   PubMed Web of Science ®Google Scholar
• Powell M. F. Drug Delivery Issues in Vaccine Development. Pharm. Res. 1996; 13: 1777–1785
   PubMed Web of Science ®Google Scholar
• Li J. K., Wang N., Wu X. S. A Novel Biodegradable System Based on Gelatin Nanoparticles and Poly(Lactide-co-Glycolide) Microspheres for Protein and Peptide Drug Delivery. J. Pharm. Sci. 1997; 86: 891–895
   PubMed Web of Science ®Google Scholar
• Inoue T., Chen G. H., Nakamae K., Hoffman A. S. A Hydrophobically-Modified Bioadhesive Polyelectrolyte Hydrogel for Drug Delivery. J. Control. Release 1997; 49: 167–176
   Web of Science ®Google Scholar
• Tabata Y., Hijikata S., Ikada Y. Enhanced Vascularization and Tissue Granulation by Basic Fibroblast Growth Factor Impregnated in Gelatin Hydrogels. J. Control. Release 1994; 31: 189–199
   Web of Science ®Google Scholar
• Konar N., Kim C. J. Drug Release from Drug-Polyanion Complex Tablets: Poly(Acrylamido-2-Methyl-1-Propanesul-Fonate Sodium-co-Methyl Methacrylate). J. Control. Release 1999; 57: 141–150
   PubMed Web of Science ®Google Scholar
• Nujoma Y. N., Kim C. J. A Designer's Polymer as an Oral Drug Carrier (Tablet) with Pseudo-Zero Order Release Kinetics. J. Pharm. Sci. 1996; 85: 1091–1095
   PubMed Web of Science ®Google Scholar
• Konar N., Kim C. J. Water-Soluble Polycations as Oral Drug Carriers (Tablets). J. Pharm. Sci. 1997; 86: 1339–1344
   PubMed Web of Science ®Google Scholar
• Thünemann A. Immobilization of Retinoic Acid by Cationic Polyelectrolytes. Langmuir 1997; 13: 6040–6046
   Web of Science ®Google Scholar
• Dumitriu S., Chornet E. Inclusion and Release of Proteins from Polysaccharide-Based Polyion Complexes. Adv. Drug Delivery Rev. 1998; 31: 223–246
   PubMed Web of Science ®Google Scholar
• Xia J., Dubin P. L., Kim Y., Muhoberac B. B., Klimkowski V. J. Electrophoretic and Quasi-Elastic Light Scattering of Soluble Protein–Polyelectrolyte Complexes. J. Phys. Chem. 1993; 97: 4528–4534
   Web of Science ®Google Scholar
• Gao J. Y., Dubin P. L., Muhoberac B. B. Capillary Electrophoresis and Dynamic Light Scattering Studies of Structure and Binding Characteristics of Protein–Polyelectrolyte Complexes. J. Phys. Chem. 1998; 102(B)5529–5535
   Google Scholar
• Wen Y-p., Dubin P. L. Potentiometric Studies of the Interaction of Bovine Serum Albumin and Poly (Dimethyldiallyammonium Chloride). Macromolecules 1997; 30: 7856–7861
   Web of Science ®Google Scholar
• Mattison K. W., Brittain I. J., Dubin P. L. Protein–Polyelectrolyte Phase Boundaries. Biotechnol. Prog. 1995; 11: 632–637
   Web of Science ®Google Scholar
• Sato T., Mattison K. W., Dubin P. L., Kamachi M., Morishima Y. Effect of Protein Aggregation on the Binding of Lysozyme to Pyrene-Labeled Polyanions. Langmuir 1998; 14: 5430–5437
   Web of Science ®Google Scholar
• Mattison K. W., Dubin P. L. Description and Characterization of Soluble Protein–Polyelectrolyte Complexes. Polym. Prep. 1998; 39: 667–668
   Google Scholar
• Kudryashova E. V., Gladilin A. K., Vakurov A. V., Heitz F., Levashov A. V., Mazhaev V. V. Enzyme–Polyelectrolyte Complexes in Water–Ethanol Mixtures: Negatively Charged Groups Artificially Introduced into α-Chymotrypsin Provide Additional Activation and Stabilization Effects. Biotech. Bioeng. 1997; 55: 267–277
   PubMedGoogle Scholar
• Kokufuta E., Takahashi K. Stoichiometric Complexation of Bovine Trypsin with Potassium Poly(Vinyl Alcohol Sulfate) and Enzyme Activity of the Complex. Polymer 1990; 31: 1177–1182
   Web of Science ®Google Scholar
• Pierce B. L.J., Gibson T. D., Bunnel P. A Preliminary Model and Evidence for the Mechanism of Stabilization of Analytical Enzymes in Aqueous Solution by Electrolyte and Sugar Derivatives. Spec. Publ.-R. Soc. Chem. 1998; 167: 54–60
   Google Scholar
• Muniruzzaman M., Hijikata T. S., Nagano A., Ikada Y. Structure Change of Basic Fibroblast Growth Factor Through Gelatin Complexation. Polym. Prep. 1998; 39: 247–248
   Google Scholar
• Edelman E. R., Mathiowitz E., Langer R., Klagsbrun M. Controlled and Modulated Release of Basic Fibroblast Growth Factor. Biomaterials 1991; 12: 619–626
   PubMed Web of Science ®Google Scholar
• Thompson J. A., Anderson K. D., Dipietro J. M., Zwiebel J. A., Zametta M., Anderson W. F., Macing T. Site-Directed Neovessel Formation In Vivo. Science 1988; 241: 1349–1352
   PubMed Web of Science ®Google Scholar
• Putnam D., Langer R. Poly(4-Hydroxy-L-Proline Ester): Low-Temperature Polycondensation and Plasmid DNA Complexation. Macromolecules 1999; 32: 3658–3662
   Web of Science ®Google Scholar
• Tsung M., Burgess D. J. Preparation and Stabilization of Heparin/Gelatin Complex Coacervate Microspheres. J. Pharm. Sci. 1997; 86: 603–607
   PubMed Web of Science ®Google Scholar
• Burgess D. J. Practical Analysis of Complex Coacervate Systems. J. Colloid Interf. Sci. 1990; 140: 227–232
   Web of Science ®Google Scholar
• Burgess D. J., Carless J. E. Microelectrophoretic Studies of Gelatin and Acacia for the Prediction of Complex Coacervation. J. Colloid Interf. Sci. 1984; 98: 1–8
   Web of Science ®Google Scholar
• Jiang H. L., Zhu K. J. Polyanion/Gelatin Complexes as pH-Sensitive Gels for Controlled Protein Release. J. Appl. Polym. Sci., in press
   Google Scholar
• Jiang H. L., Zhu K. J. Pulsatile Protein Release from Laminated Device Composed of Polyanhydrides and pH-Sensitive Complexes. Int. J. Pharm. 2000; 194: 51–60
   PubMed Web of Science ®Google Scholar
• Katchalesky A., Eisenberg H. J. Polym. Sci. 1951; 6: 145–149
   Google Scholar
• Cai J., Zhu K. J. Preparation, Characterization, and Biodegradable Characteristics of Poly(D,L-Lactide-co-Trimethylene Carbonate). Polym. Int. 1997; 42: 373–379
   Web of Science ®Google Scholar
• Tsuboi A., Izumi T., Hirata M., Xia J. L., Dubin P. L., Kokufuta E. Complexation of Proteins with a Strong Polyanion in an Aqueous Salt-Free System. Langmuir 1996; 12: 6295–6303
   Web of Science ®Google Scholar
• Ritger P. L., Peppas N. A. A Simple Equation for Description of Solute Release. I. Fickian and Non-Fickian Release from Nonswellable Devices in the Form of Slabs, Spheres, Cylinders, or Discs. J. Control. Release 1987; 5: 23–26
   Google Scholar
• Calvo P., Remuňan-López C., Vila-Jato J. L., Alonso M. J. Chitosan and Chitosan-Ethylene Oxide-Propylene Oxide Block Copolymer Nanoparticles as Novel Carriers for Proteins and Vaccines. Pharm. Res. 1997; 14: 1431–1436
   PubMed Web of Science ®Google Scholar
• Ramkissoon-Ganorkar C., Gutowska A., Liu F., BaudyŠ M., Kim S. W. Polymer Molecular Weight Alters Properties of pH-/Temperature-Sensitive Polymeric Beads. Pharm. Res. 1999; 16: 819–827
   PubMed Web of Science ®Google Scholar
• Lowman A. M., Morishita M., Kajita M., Nagai T., Peppas N. A. Oral Delivery of Insulin using pH-Responsive Complexation Gels. J. Pharm. Sci. 1999; 88: 933–937
   PubMed Web of Science ®Google Scholar
• Tsuchida E., Abe K. A. D. Wilson, H. J. ProsserPolyelectrolyte Complexes. Development in Ionic Polymers, . Elsevier Applied Sciences, London 1986; 191–205
   Google Scholar
• Leo E., Pecquet S., Rojas J., Couvreur P., Fattal E. Changing the pH of the External Aqueous Phase May Modulate Protein Entrapment and Delivery From Poly(Lactide-co-Glycolide) Microspheres Prepared by a w/o/w Solvent Evaporation Method. J. Microencapsulation 1998; 15: 421–430
   PubMed Web of Science ®Google Scholar
• Hopfenberg H. B. D. R. Paul, F. W. HarrisControlled Release from Erodible Slabs, Cylinders and Spheres. Controlled Release Polymeric Formulations, . ACS Symposium Series, 33, American Chemical Society, Washington, DC 1976; 26–32
   Google Scholar
• Kwon I. C., Bae Y. H., Kim S. W. Electrically Erodible Polymer Gel for Controlled Release of Drugs. Nature 1991; 354: 291–293
   PubMed Web of Science ®Google Scholar
• Antonini E., Brunori M. Hemoglobin and Myoglobin in Their Reactions with Lignands. North-Holland, New York 1971
   Google Scholar
• Johnson O. L., Cleland J. L., Lee H. J., Charnis M., Duenas E., Jaworowicz W., Shepard D., Shahzamani A., Jones A. J.S., Putney S. D. A Month-Long Effect from a Single Injection of Microencapsulated Human Growth Hormone. Nature Med. 1996; 2: 795–799
   PubMed Web of Science ®Google Scholar