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Research Article

Scaleup of a Pharmaceutical Granulation in Planetary Mixers

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Pages 145-150 | Received 23 Mar 1998, Accepted 13 Jul 1998, Published online: 22 Apr 1999

REFERENCES

  • Cliff M. J., Parker M. D. Scale-up of mixer granulators. in Proceedings of the 12th Interphase Conference. 1990, 5/17–5/32
  • Landin M., York P., Cliff M. J., Rowe R. C., Wigmore A. J. Scale up of a pharmaceutical granulation in fixed bowl mixer granulator. Int. J. Pharm. 1996; 133: 127–131
  • Faure A., Landin M., Grimsey I. M., York P., Cliff M. J., Rowe R. C., Wigmore A. J. Scale up of a pharmaceutical granulation in two production scale fixed bowl mixer granulators. Proc. 16th Pharm. Technol. Conf. 1997. 2: 187–191
  • Faure A., Grimsey I. M., York P., Cliff M. J., Rowe R. C. A methodology for the optimisation of wet granulation in a model planetary mixer. Pharm. Dev. Technol. 1998; 3(3)413–422
  • Holland F. A., Chapman F. S. Liquid Mixing and Processing in Stirred Tanks. Chapman and Hall, London 1966; 2: 22–49, Chapter 2
  • Parker M. D., Rowe R. C., Upjohn N. G. Mixer torque rheometry: a method for quantifying the consistency of wet granulations. Pharm. Technol. Int. 1990; 2(8)50–62
  • Shiromani P. K., Bavitz J. F. Studies on a diabasic calcium phosphate-mannitol matrix tablet formulation—a complimentary combination. Drug Dev. Ind. Pharm. 1988; 14(10)1375–1387

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