635
Views
59
CrossRef citations to date
0
Altmetric
Research Article

Investigation of Excipient Type and Level on Drug Release from Controlled Release Tablets Containing HPMC

, , , &
Pages 181-193 | Received 16 Apr 2001, Accepted 24 Jul 2001, Published online: 29 May 2002

REFERENCES

  • Alderman D.A. A Review of Cellulose Ethers in Hydrophilic Matrices for Oral Controlled Release Dosage Forms. Int. J. Pharm. Technol. Prod. Manuf. 1984; 5: 1–9
  • Using Methocel Cellulose Ethers for Controlled Release of Drugs in Hydrophilic Matrix Systems. The Dow Chemical Company, Midland, MI 2000; Vol. 12: 18–20
  • Abdou H.M. Effect of the Physicochemical Properties of the Drug on Dissolution. Dissolution, Bioavailability and Bioequivalence. Mack Publishing, Easton, PA 1989; 53–72
  • Vazquez M.J., Perez-Marcos B., Gomez-Amoza J.L., Martinez-Pacheco R., Souto C., Concheiro A. Influence of Technological Variables on Release of Drugs from Hydrophilic Matrices. Drug Dev. Ind. Pharm. 1992; 18: 1355–1375
  • Velasco M.V., Ford J.L., Rowe P., Rajabi-Siahboomi A.R. Influence of Drug: Hydroxypropylmethylcellulose ratio, Drug and Polymer Particle Size and Compression Force on the Release of Diclofenac Sodium from HPMC Tablets. J. Control. Rel. 1999; 57: 75–85
  • Hirschorn J.O., Kornblum S.S. Dissolution of Poorly Water-Soluble Drugs II: Excipient Dilution and Force of Compression Effects on Tablets of a Quinazolinone Compound. J. Pharm. Sci. 1971; 60: 445–448
  • Ford J.L., Rubenstein M.H., McCaul F., Hogan J.E., Edger P.J. Importance of Drug Type, Tablet Shape and Added Diluents on Drug Release Kinetics from Hydroxypropylmethylcellulose Matrix Tablets. Int. J. Pharm. 1987; 40: 223–234
  • Huber H.E., Christenson G.L. Utilization of Hydrophilic Gums for the Control of Drug Substance Release from Tablet Formulations II. Influence of Tablet Hardness and Density on Dissolution Behaviour. J. Pharm. Sci. 1968; 57: 164–166
  • Krogel I., Bodmeier R. Development of a Multifunctional Matrix Drug Delivery System Surrounded by an Impermeable Cylinder. J. Control. Rel. 1999; 61: 43–50
  • Cheong L.W.S., Heng P.W.S., Wong L.F. Relationship Between Polymer Viscosity and Drug Release from a Matrix System. Pharm. Res. 1992; 9: 1510–1514
  • Ford J.L., Rubinstein M.H., Hogan J.E. Formulation of Sustained Release Promethazine Hydrochloride Tablets Using Hydroxypropylmethylcellulose Matrices. Int. J. Pharm. 1985; 24: 327–338
  • Tahara K., Yamamoto K., Nishihata T. Overall Mechanism Behind Matrix Sustained Release (SR) Tablets Prepared with Hydroxypropyl Methylcellulose 2910. J. Control. Rel. 1995; 35: 59–66
  • Mitchell K., Ford J.L., Armstrong D.J., Elliot P., Rostron C., Hogan J.E. The Influence of Concentration on the Release of Drugs from Gels and Matrices Containing Methocel. Int. J. Pharm. 1993; 100: 155–163
  • Shah N., Zhang G., Apelian V., Zeng F., Infield M.H., Malick A.W. Prediction of Drug Release from Hydroxypropyl Methylcellulose (HPMC) Matrices: Effect of Polymer Concentration. Pharm. Res. 1993; 10: 1693–1695
  • Ford J.L., Rubinstein M.H., Hogan J.E. Propranolol Hydrochloride and Aminophylline Release from Matrix Tablets Containing Hydroxypropylmethylcellulose. Int. J. Pharm. 1985; 24: 339–350
  • Mitchell K., Ford J.L., Armstrong D.J.P., Elliot N.C., Hogan J.E., Rostron C. The Influence of Substitution Type on the Performance of Methylcellulose and Hydroxypropylmethylcellulose in Gels and Matrices. Int. J. Pharm. 1993; 100: 143–154
  • Lapidus H., Lordi N.G. Drug Release from Compressed Hydrophilic Matrices. J. Pharm. Sci. 1968; 57: 1292–1301
  • Daly P.B., Davis S.S., Kennerley J.W. The Effect of Anionic Surfactants on the Release of Chlorpheniramine from a Polymer Matrix Tablet. Int. J. Pharm. 1984; 18: 201–205
  • , The United States Pharmacopeial Convention. USP 24/NF 19; National Publishing: Philadelphia, PA.
  • Shah V.P., Tsong Y., Sathe P., Liu; J. In Vitro Dissolution Profile Comparison-Statistics and Analysis of the Similarity Factor, f2. Pharm. Res. 1998; 15: 889–896
  • Shah V.P., Tsong Y., Sathe P., Williams R.L. Dissolution Profile Comparison Using Similarity Factor, f2. Dissolution Technol. 1999; 6(3)15
  • Moore J.W., Flanner H.H. Mathematical Comparison of Curves with an Emphasis on In Vitro Dissolution Profiles. Pharm. Technol. 1996; 20: 64, 66,68,70,72,74
  • Greenblatt D.J., Arendt R.M., Abernethy D.R., Giles H.G., Sellers E.M., Shader R.I. In Vitro Quantitation of Benzodiazepine Lipophilicity: Relation to In Vivo Distribution. Br. J. Anaesth. 1983; 55: 985–989
  • Garzone P.D., Kroboth P.D. Pharmacokinetics of the Newer Benzodiazepines. Clin. Pharmacokin. 1989; 16: 337–364
  • Laihanen N., Muttonen E., Laaksonen M. Solubility and Intrinsic Rate of Alprazolam Crystal Modifications. Pharm. Dev. Technol. 1996; 1(4)373–380
  • Laihanen N., Yliruusi J. Physical Stability of Alprazolam Dihydrate: Intact, Ground and Tabletted Samples Compatibility with Certain Commonly Used Tabletting Excipients. S.T.P. Pharm. Sci. 1996; 6: 403–409
  • Hixson A.W., Crowell J.H. Dependence of Reaction Velocity upon Surface and Agitation I. Theoretical Consideration. Ind. Eng. Chem. 1931; 23: 923–931
  • Peppas N.A. Analysis of Fickian and Non-fickian Drug Release from Polymers. Pharm. Acta Helv. 1985; 60: 110–111
  • Peppas N.A., Ritger P.L. A Simple Equation for Description of Solute Release I. Fickian and Non-Fickian Release from Non-swellable Devices in the Form of Slabs, Spheres, Cylinders or Disc. J. Control. Rel. 1987; 5: 23–36
  • Peppas N.A., Ritger P.L. A Simple Equation for Description of Solute Release II. Fickian and Anomalous Release from Swellable Devices. J. Control. Rel. 1987; 5: 37–42
  • Korsmeyer R.W., Gurny R., Doelker E., Buri P., Peppas N.A. Mechanisms of Solute Release from Porous Hydrophilic Polymers. Int. J. Pharm. 1983; 15: 25–35
  • Skoug J.W., Mikelsons M.V., Vigneron C.N., Stemm N.L. Qualitative Evaluation of the Mechanism of Release of Matrix Sustained Release Dosage Forms by Measurement of Polymer Release. J. Control. Rel. 1993; 27: 227–245
  • Eyjolfsson R. Hydroxypropyl Methylcellulose Mixtures: Effects and Kinetics of Release of an Insoluble Drug. Drug Dev. Ind. Pharm. 1999; 25: 667–669

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.