Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 7, 2002 - Issue 2
Submit an article Journal homepage
454
Views
54
CrossRef citations to date
0
Altmetric
Research Article

Intratumoral Administration of Paclitaxel in an In Situ Gelling Poloxamer 407 Formulation

Mansoor M. Amiji Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, 02115, U.S.A.
,
Phung-Kim Lai Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, 02115, U.S.A.
,
Dinesh B. Shenoy Dr. T.M.A. Pai Pharmaceutical Research Centre, College of Pharmaceutical Sciences, Manipal, Karnataka State, 576 119, India
&
Mahadev Rao Dr. T.M.A. Pai Pharmaceutical Research Centre, College of Pharmaceutical Sciences, Manipal, Karnataka State, 576 119, India
Pages 195-202 | Received 23 Apr 2000, Accepted 11 Aug 2000, Published online: 29 May 2002

REFERENCES

  • Jain R.K. Delivery of Molecular and Cellular Medicine to Solid Tumors. Adv. Drug Delivery Rev. 1997; 26: 71–90
  • Fung L.K., Saltzman W.M. Polymeric Implants for Cancer Chemotherapy. Adv. Drug Delivery Rev. 1997; 26: 209–230
  • Dhanikula A.B., Panchagnula R. Localized Paclitaxel Delivery. Int. J. Pharm. 1999; 183: 85–100
  • Panchagnula R. Pharmaceutical Aspects of Paclitaxel. Int. J. Pharm. 1998; 172: 1–15
  • Spencer C.M., Faulds D. Paclitaxel: A Review of Its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in the Treatment of Cancer. Drugs 1994; 48: 794–847
  • Okataba A.M., Arsenault A.L., Hunter W.L. Taxol: A Potent Inhibitor of Normal and Tumor-Induced Angiogenesis. Proc. Am. Assoc. Cancer Res. 1995; 36: 454
  • Millenbaugh N.J., Gan Y., Au J.L.-S. Cytostatic and Apoptotic Effects of Paclitaxel in Human Ovarian Tumors. Pharm. Res. 1998; 15: 122–127
  • Mote P.A., Davey M.W., Davey R.A., Oliver L. Paclitaxel Sensitizes Multidrug Resistant Cells to Radiation. Anticancer Drugs 1996; 7: 182–188
  • Nicholson K.M., Bibby M.C., Phillips R.M. Influence of Drug Exposure Parameters on the Activity of Paclitaxel in Multicellular Spheroids. Eur. J. Cancer 1997; 33: 1291–1298
  • Harper E., Dang W., Lapidus R.G., Garver R.I., Jr. Enhanced Efficacy of a Novel Controlled Release Paclitaxel Formulation (PACLIMER Delivery System) for Local-Regional Therapy of Lung Cancer Tumor Nodules In Mice. Clin. Cancer Res. 1999; 5: 4242–4248
  • Winternitz C.I., Jackson J.K., Okataba A.M., Burt H.M. Development of Polymeric Surgical Paste Formulation for Taxol. Pharm. Res. 1996; 13: 368–375
  • Park E.-S., Maniar M., Shah J.C. Biodegradable Polyanhydride Devices of Cefazolin Sodium, Bupivacaine, and Taxol for Local Drug Delivery: Preparation and Kinetics and Mechanism of In Vitro Release. J. Control. Release 1998; 52: 179–189
  • Lundsted L.G., Schmolka I.R. R.J. CeresaThe Synthesis and Properties of Block Copolymer Surfactants. Block and Graft Copolymerization, . John Wiley and Sons, New York, NY 1976; 1–111
  • Paavola A., Yliruusi J., Kojimoto Y., Kalso E., Wahlstrom T., Rosenberg P. Controlled Release of Lidocaine from Injectable Gels and Efficacy in Rat Sciatic Nerve Block. Pharm. Res. 1995; 12: 1997–2002
  • Katakam M., Ravis W.R., Banga A.K. Controlled Release of Human Growth Hormone in Rats Following Parenteral Administration of Poloxamer Gels. J. Control. Release 1997; 49: 21–26
  • Pandit N.K., McIntyre H.J. Cosolvent Effects on the Gel Formation and Gel Melting Transitions of Pluronic® F127 Gels. Pharm. Dev. Technol. 1997; 2: 181–184
  • Lai P.K., Nguyen T., Amiji M. Novel Thermogelling Paclitaxel Formulation for Localized Delivery. Trans. Soc. Biomater. 1999; 22: 321
  • Rao M., Kamath R., Rao M.N.A. Protective Effect of Selenomethionine Against Cisplatin-Induced Nephrotoxicity in C57BL/6J Mice Bearing B16F1 Melanoma Without Reducing Antitumor Activity. Pharm. Pharmacol. Commun. 1998; 4: 549–552
  • Sharma D., Chelvi T.P., Kaur J., Chakravorty K., De T.K., Maitra A., Ralhan R. Novel Taxol® Formulations: Polyvinylpyrrolidone Nanoparticle-Encapsulated Taxol® for Drug Delivery in Cancer Therapy. Oncol. Res. 1996; 8: 281–286
  • Vadnere M., Amidon G., Lindenbaum S., Haslam J.L. Thermodynamic Studies on the Gel–Sol Transition of Some Pluronic Polyols. Int. J. Pharm. 1984; 22: 207–218

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.