An Adjusted Pharmacokinetic Equation for Predicting Drug Levels In Vivo Based on In Vitro Square Root of Time Release Kinetics

REFERENCES

• Chiao C.S., Robinson J.R. A.R. GennaroSustained-Release Drug Delivery Systems. Remington, the Science and Practice of Pharmacy, . 19th Ed., Mack Publishing Company, Pennsylvania 1995; 1660–1675
   Google Scholar
• Heller J. J.R. Robinson, V.H.L. LeeFundamentals of Polymer Science. Controlled Drug Delivery, . 2nd Ed., Marcel Dekker, Inc., New York 1987; 140–174
   Google Scholar
• Lee P.I. Kinetics of Drug Release from Hydrogel Matrices. J. Control. Release 1985; 2: 277–288
   Google Scholar
• Lee P.I., Peppas N.A. Prediction of Polymer Dissolution in Swellable Controlled-Release Systems. J. Control. Release 1987; 6: 207–215
   Google Scholar
• Ju R.T.C., Nixon P.R., Patel M.V. New Scaling Laws for Predicting Polymer and Drug Release Based on the Polymer Dis-entanglement Concentration and the Diffusion Layer. J. Pharm. Sci. 1995; 84(12)1455–1463
   PubMed Web of Science ®Google Scholar
• Gao P., Skoug J.W., Nixon P.R., Ju R., Stemm N.L., Sung K.C. Swelling of Hydroxypropyl Methylcellulose Matrix Tablets Mechanistic Study of the Influence of Formulation Variables on Matrix Performance and Drug Release. J. Pharm. Sci. 1996; 85(7)732–740
   PubMed Web of Science ®Google Scholar
• Sung K.C., Nixon P.R., Skoug J.W., Ju R., Gao P., Topp E.M., Patel M.V. Effect of Formulation Variables on Drug and Polymer Release from HPMC-Based Matrix Tablets. Int. J. Pharm. 1996; 142: 53–60
   Web of Science ®Google Scholar
• Tahara K., Yamamoto K., Nishihata T. Overall Mechanism Behind Matrix Sustained Release (SR) Tablets Prepared with Hydroxy-propyl Methylcellulose 2910. J. Control. Release 1995; 35: 59–66
   Web of Science ®Google Scholar
• Vazquez M.J., Casalderrey M., Duro R., Gomez J.L., Pacheco R.M., Souto C., Concheiro A. Atenolol Release from Hydrophilic Matrix Tablets with HPMC Mixtures as the Gelling Agent: Effects of the Viscosity of the HPMC Mixture. Eur. J. Pharm. Sci. 1996; 4: 39–48
   Web of Science ®Google Scholar
• Roshdy M., Schwartz J., Schnaare R. A Novel Method for Measuring Gel Strength of Controlled Release Hydrogel Tablets Using a Cone/Plate Rheometer. Pharm. Dev. Technol. 2001; 6(2)1–11
   PubMed Web of Science ®Google Scholar
• Roshdy M.N., Schnaare R.L., Schwartz J.B. The Effect of Formulation Composition and Dissolution Parameters on the Gel Strength of Controlled Release Hydrogel Tablets. Pharm. Dev. Technol. 2001; 6(4)583–593
   PubMed Web of Science ®Google Scholar
• Roshdy M.N., Schnaare R.L., Sugita E.T., Schwartz J.B. Effect of Controlled Release Tablets Hydrogel Strength on In Vitro/In Vivo Correlation. Pharm. Dev. Technol. 2002; 7(2)121–134
   Google Scholar
• Bolton S. Pharmaceutical Statistics: Practical and Clinical Applications. 2nd Ed., Marcel Dekker, Inc., New York 1990; 271–285
   Google Scholar
• Hussein Z., Bialer M., Friedman M., Raz I. Comparative Pharmacokinetic Evaluation of Sustained-Release Theophylline Formulations in Dogs and Humans. Int. J. Pharm. 1987; 37: 97–102
   Google Scholar
• Shiu G.K., LeMarchand A., Sager A., Velagapudi R.B., Skelly J.P. The Beagle Dog as an Animal Model for a Bioavailability Study of Controlled-Release Theophylline Under the Influence of Food. Pharm. Res. 1989; 6(12)1039–1042
   PubMed Web of Science ®Google Scholar
• Cook C.S., Hauswald C.L., Grahn A.Y., Kowalski K., Karim A., Koch R., Schoenhard G.L., Oppermann J.A. Suitability of the Dog as an Animal Model for Evaluating Theophylline Absorption and Food Effects from Different Formulations. Int. J. Pharm. 1990; 60: 125–132
   Web of Science ®Google Scholar
• Liu C.Y., Amidon G.L., Berardi R.R., Fleisher D., Youngberg C., Dressman J.B. Comparison of Gastrointestinal pH in Dogs and Humans: Implications on the Use of the Beagle Dog as a Model for Oral Absorption in Humans. J. Pharm. Sci. 1986; 75: 271–274
   PubMed Web of Science ®Google Scholar
• Yu Z., Schwartz J., Sugita E. Theophylline Controlled-Release Formulations: In Vivo/In-Vitro Correlations. Biopharm. Drug Dispos. 1996; 17: 259–272
   PubMed Web of Science ®Google Scholar
• Yu Z. Theophylline Controlled Release Formulations: In Vivo–In Vitro Correlation. University of the Sciences in Philadelphia, Philadelphia, PA
   Google Scholar
• Welling P.G. Oral Controlled Drug Administration: Pharmacokinetic Considerations. Drug Dev. Ind. Pharm. 1983; 9(7)1185–1225
   Web of Science ®Google Scholar
• Welling P.G., Dobrinska M.R. J.R. RobinsonMultiple Dosing of Sustained Release Systems. Sustained and Controlled Release Drug Delivery Systems, . Marcel Dekker, Inc., New York 1978; 631–716
   Google Scholar
• Marcos B.P., Ford J.L., Armstrong D.J., Elliott P.N.C., Rostron C., Hogan J.E. Influence of pH on the Release of Propranolol Hydrochloride from Matrices Containing HPMC K4M and Carbopol 974. J. Pharm. Sci. 1996; 85(3)330–334
   PubMed Web of Science ®Google Scholar
• Mitchell K., Ford J.L., Armstrong D.J., Elliott P.N.C., Rostron C., Hogan J.E. The Influence of Additives on the Cloud Point, Disintegration and Dissolution of Hydroxypropyl Methylcellulose Gels and Matrix Tablets. Int. J. Pharm. 1990; 66: 233–242
   Web of Science ®Google Scholar
• Lindahl A., Ungell A.L., Knuston L., Lennernas H. Characterization of Fluids from the Stomach and Proximal Jejunum in Men and Women. Pharm. Res. 1997; 14(4)497–502
   PubMed Web of Science ®Google Scholar
• Shargel L., Yu A.B. Applied Biopharmaceutics and Pharmacokinetics. Appleton & Lange, Connecticut 1993; 111–133
   Google Scholar
• Kararli T.T. Comparison of the Gastrointestinal Anatomy, Physiology, and Biochemistry of Humans, and Commonly Used Laboratory Animals. Biopharm. Drug Dispos. 1995; 16: 351–380
   PubMed Web of Science ®Google Scholar