Effect of pH on In Vitro Permeation of Ondansetron Hydrochloride Across Porcine Buccal Mucosa

References

• Gandhi, R.B.; Robinson, J.R. Oral cavity as a site for bioadhesive drug delivery.Adv. Drug Deliv. Rev. 1994, 13 (1–2), 43–74., [CSA]
   Web of Science ®Google Scholar
• Patterson, K.W.; Keane, P.W. Use of the buccal route for the administration of an antiemetic.Pharm. Res. 1989, 6 (2), 160–166., [CROSSREF]
   PubMedGoogle Scholar
• Rathbone, M.J.; Hasgraft, J. Absorption of drugs from the human oral cavity.Int. J. Pharm. 1991, 74 (1), 9–24., [CROSSREF]
   Web of Science ®Google Scholar
• Khanvilkar, K.; Donovan, M.D.; Flanagan, D.R. Drug transfer through mucus.Adv. Drug Deliv. Rev. 2001, 48 (2–3), 173–193., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Senel, S.; Hincal, A.A. Drug permeation enhancement via buccal route: possibilities and limitations.J. Control. Release 2001, 72 (1–3), 133–144., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Junginger, H.E.; Hoogstraate, J.A.; Verhoef, J.C. Recent advances in buccal drug delivery and absorption–in vitro and in vivo studies.J. Control. Release 1999, 62 (1–2), 149–159., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Chen, L.L.; Chetty, D.J.; Chien, Y.W. A mechanistic analysis to characterize oramucosal permeation properties.Int. J. Pharm. 1999, 184 (1), 63–72., [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Al-sayed-omar, O.; Johnson, A.; Turner, P. Influence of pH on the buccal absorption of morphine sulphate and its major metabolite, morphine-3-glucuronide.J. Pharm. Pharmcol. 1987, 39 (1), 934–935.
   PubMedGoogle Scholar
• Nair, M.K.; Chetty, D.J.; Ho, H.; Chein, Y.W. Biomembrane permeation of nicotine: mechanistic studies with porcine mucosae and skin.J. Pharm. Sci. 1997, 86 (2), 257–262., [PUBMED], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Nielson, M.N.; Rassing, M.R. Nicotine permeability across the buccal TR 146 cell culture model and porcine mucosa in vitro: effect of pH and concentration.Eur. J. Pharm. Sci. 2002, 16 (3), 151–157., [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Deneer, V.H.; Drese, G.B.; Roemele, P.E.; Verhoef, J.C.; Lie-A-Huen, L.; Kingma, J.H.; Brouwers, J.R.; Junginger, H.E. Buccal transport of flecainide and sotalol: effect of a bile salt and ionization state.Int. J. Pharm. 2002, 241 (1), 127–134., [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Coutel-Egros, A.; Maitani, Y.; Veillard, M.; Machida, Y.; Nagai, T. Combined effects of pH, cosolvent and penetration enhancers on the in vitro buccal absorption of propanolol through excised hamster cheek pouch.Int. J. Pharm. 1992, 84 (2), 117–128., [CROSSREF]
   Web of Science ®Google Scholar
• Nielsen, H.M.; Rassing, M.R. TR146 cells grown on filters as a model of human buccal epithelium: III. Permeability enhancement by different pH value, different osmolarity value, and bile salts.Int. J. Pharm. 1999, 185 (2), 215–225., [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMedGoogle Scholar
• Gandhi, R.B.; Robinson, J.R. Mechanisms of penetration enhancement for transbuccal delivery of salicylic acid.Int. J. Pharm. 1992, 85 (1–3), 129–140., [CROSSREF]
   Web of Science ®Google Scholar
• Shojaei, A.H.; Berner, B.; Li, X. Transbuccal delivery of acyclovir: I. In vitro determination of buccal transport.Pharm. Res. 1998, 15 (8), 1182–1188., [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Beckett, A.H.; Moffat, A.C. Correlation of partition coefficients in N-heptane-aqueous systems with buccal absorption data for a series of amines and acids.J. Pharm. Pharmcol. 1969, 21 (Suppl.), 144S–150S.
   Google Scholar
• Beckett, A.H.; Triggs, E.J. Buccal absorption of basic drugs and its application as an in vivo model passive drug transfer through lipid membrane.J. Pharm. Pharmcol. 1967, 19 (Suppl.), 31S–41S.
   PubMedGoogle Scholar
• Le Brun, P.P.H.; Fox, P.L.A.; De Vries, M.E.; Bodde, H.E. In vitro penetration of some β-adrenoreceptor blocking drugs through porcine buccal mucosa.Int. J. Pharm. 1989, 49 (2), 141–145., [CROSSREF]
   Google Scholar
• Chen, L.; Hui-Nan, X.; Xiao-Ling, L. In vitro permeation of tetramethylpyrazine across porcine buccal mucosa.Acta. Pharmacol. Sin. 2002, 23 (9), 792–796., [CSA]
   PubMed Web of Science ®Google Scholar
• Garren, K.W.; Repta, A.J. Buccal drug absorption. II. In vitro diffusion across the hamster cheek pouch.J. Pharm. Sci. 1989, 78 (2), 160–164., [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Chettu, D.J.; Chen, L.L.; Chien, Y.W. Characterization of captopril sublingual permeation: determination of routes and mechanisms.J. Pharm. Sci. 2001, 90 (11), 1868–1877., [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ishizawa, T.; Hayashi, M.; Awazu, S. Paracellular and transcellular permeabilities of fosfomycin across small intestinal membrane of rat and rabbit by voltage-clamp method.J. Pharmacobio-dyn. 1991, 14 (10), 583–589., [PUBMED], [INFOTRIEVE]
   PubMedGoogle Scholar
• Toropainen, E.; Ranta, V.; Vellonen, K.; Palmgren, J.; Tavitie, A.; Laavola, M.; Suhonen, P.; Hamalanen, K.M.; Auriola, S.; Urtti, A. Paracellular and passive transcellular permeability in immortalized human corneal epithelial cell culture model.Eur. J. Pharm. Sci. 2003, 20 (1), 99–106., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Zhang, H.; Robinson, J.R. Swarbrick, J., Boylan, J.CIn vitro methods for measuring permeability of the oral mucosa. In Oral Mucosal Drug Delivery, 1st Ed.; ., Eds.; Marcel Dekker, Inc.: New York, 1996; 85–100.
   Google Scholar
• Markham, A.; Sorkim, E.M. Ondansetron. An update of its therapeutic use in chemotherapy-induced and postoperative nausea and vomiting.Drugs 1993, 45 (6), 931–952., [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Veuillez, F.; Kalia, Y.N.; Jacques, Y.; Deshusses, J.; Buri, P. Factors and strategies for improving buccal absorption of peptides.Eur. J. Pharm. Biopharm. 2001, 51 (2), 93–109., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Takahashi, K.; Sakano, H.; Rytting, H.J.; Numata, N.; Kuroda, S. Influence of pH on the permeability of p-toluidine and aminopyrine through shed snake skin as a model membrane.Drug. Dev. Ind. Pharm. 2001, 27 (2), 159–164., [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Hoogstraate, A.J.; Senel, S.; Cellander, C.; Verhoef, J.C.; Junginger, H.E.; Bodde, H.E. Effects of bile salts on transport routes and routes of FITC-labelled compounds across porcine buccal epithelium in vitro.J. Control. Release 1996, 40 (3), 211–221., [CROSSREF]
   Web of Science ®Google Scholar
• Tsutsumi, K.; Obata, Y.; Nagai, T.; Loftsson, T.; Takayama, K. Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea pigs.Int. J. Pharm. 2002, 238 (1–2), 161–170., [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Cui, Z.; Mumper, R.J. Buccal transmucosal delivery of calcitonin in rabbits using thin-film composite.Anesth. Analg. 1992, 74 (6), 937–938.
   Google Scholar
• Salem, I.; Lopez, RamosM.; Galan, A.C. Brittain, H., Flourey, KOndansetron hydrochloride. In Analytical Profiles of Drug Substances and Excipients; ., Eds.; Academic Press: London, 2002; 665–689.
   Google Scholar