Advanced search
Publication Cover
Hypertension in Pregnancy Volume 22, 2003 - Issue 2
Submit an article Journal homepage
49
Views
9
CrossRef citations to date
0
Altmetric
Original

Does Endothelial Nitric Oxide Synthase Gene Variation Play a Role in the Occurrence of Hypertension in Pregnancy?

Elvira Grandone Atherosclerosis and Thrombosis Unit, Division of Obstetrics and Gynaecology, Unita' di Aterosclerosi e Trombosi, I.R.C.C.S., “Casa Sollievo della Sofferenza”, Viale Cappuccini 71013, S. Giovanni Rotondo (FG), Italy
, M.D.,
Donatella Colaizzo Atherosclerosis and Thrombosis Unit, Division of Obstetrics and Gynaecology, Unita' di Aterosclerosi e Trombosi, I.R.C.C.S., “Casa Sollievo della Sofferenza”, Viale Cappuccini 71013, S. Giovanni Rotondo (FG), Italy
, Biol.Sc.,
Pasquale Martinelli Department of Obstetrics and Gynaecology, Università Federico II, Naples, Italy
, M.D.,
Giuseppe Pavone Atherosclerosis and Thrombosis Unit, Division of Obstetrics and Gynaecology, Unita' di Aterosclerosi e Trombosi, I.R.C.C.S., “Casa Sollievo della Sofferenza”, Viale Cappuccini 71013, S. Giovanni Rotondo (FG), Italy
, M.D.,
Massimo Errico Division of Internal Medicine, Unita' di Aterosclerosi e Trombosi, I.R.C.C.S., “Casa Sollievo della Sofferenza”, Viale Cappuccini 71013, S. Giovanni Rotondo (FG), Italy
, M.D.,
Gennaro Vecchione Atherosclerosis and Thrombosis Unit, Division of Obstetrics and Gynaecology, Unita' di Aterosclerosi e Trombosi, I.R.C.C.S., “Casa Sollievo della Sofferenza”, Viale Cappuccini 71013, S. Giovanni Rotondo (FG), Italy
, Biol.Sc. &
Maurizio Margaglione Department of Medical Genetics, University of Foggia, Italy
, M.D. show all
Pages 149-155 | Published online: 07 Jul 2009

References

  • Cunningham F G, Lindheimer M D. Hypertension in pregnancy. N Engl J Med 1992; 326: 927–932
  • Cooper D W, Brennecke S P, Wilton A N. Genetics of preeclampsia. Hypertens Pregnancy 1993; 12: 1–23
  • Fischer K A, Luger L, Spargo B H, Lindheimer M D. Hypertension in pregnancy: clinical pathologic correlations and remote prognosis. Medicine 1981; 60: 267–272
  • Chesley L C, Annitto J E, Cosgrove R A. The remote prognosis of eclamptic women. Am J Obstet Gynecol 1976; 124: 446–452
  • Sibai B M, El‐Nazer A, Gonzalez‐Ruiz A. Severe pre‐eclampsia in young primigravid women: subsequent pregnancy outcome and remote prognosis. Am J Obstet Gynecol 1986; 155: 1011–1016
  • Moncada S, Higgs A. The L‐Arginine‐nitric oxide pathway. N Engl J Med 1993; 329: 2002–2012
  • Moncada S, Palmer R M, Higgs E A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109–142
  • Panza J A, Quyyumi A A, Brush J E, Epstein S E. Abnormal endothelium‐dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22–27
  • Glance D G, Elder M G, Myatt L. The actions of prostaglandins and their interactions with angiotensin II in the isolated perfused human placental cotiledon. Br J Obstet Gynaecol 1986; 93: 488–494
  • Pinto A, Sorrentino R, Sorrentino P, Guerritore T, Miranda L, Biondi A, Martinelli P. Endothelial‐derived relaxing factor released by endothelial cells of human umbilical vessels and its impairment in pregnancy‐induced hypertension. Am J Obstet Gynecol 1991; 164: 507–513
  • Nishida K, Harrison D G, Navas J P, Fisher A A, Dockery S P, Uematsu M, Nerem R M, Alexander R W, Murphy T J. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J Clin Invest 1992; 90: 2092–2096
  • Wang X L, Sim A S, Badenhop R F, McCredie R M, Wilcken D EL. A smoking‐dependent risk of coronary artery disease associated with a polimorphism of the endoyhelial nitric oxide synthase gene. Nat Med 1996; 2: 41–45
  • Saiki R H, Gelfand D H, Stoffel S, Scharf S J, Higuchi R, Horn G T, Mullis K B, Erlich H A. Primer‐directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988; 239: 489–491
  • Margaglione M, Celentano E, Grandone E, Vecchione G, Cappucci G, Giuliani N, Colaizzo D, Panico S, Mancini F P, Di Minno G. Deletion polymorphism in the angiotensin‐converting enzyme gene in patients with a history of ischemic stroke. Arterioscler Thromb Vasc Biol 1996; 16: 304–309
  • Forstermann U, Closs E I, Pollock J S, Nakane M, Schwarz, Gath I, Kleinert H. Nitric oxide synthase isozymes‐characterization, purification, molecular cloning, and functions. Hypertension 1994; 23(Part 2)1121–1131
  • Janssens S P, Shimouchi A, Quetermous T, Bloch D B, Bloch K D. Cloning and expression of a cDNA encoding human endothelium‐derived relaxing factor/nitric oxide synthase. J Biol Chem 1992; 267: 14519–14522
  • Bonnardeaux A, Nadaud S, Charru A, Jeunemaitre X, Corvol P, Soubrier F. Lack of evidence for linkage of the endothelial cell nitric oxide synthase gene to essential hypertension. Circulation 1995; 91: 96–102
  • Sessa W C, Pritchard K, Seyedy N, Wang J, Hintze T H. Chronic exercise increases coronary vascular nitric oxide production and endothelial cells nitric oxide synthase gene expression. Circ Res 1994; 74: 349–353
  • Weiner C P, Lizasoain I, Baylis S A, Knowles R G, Charles I G, Moncada S. Induction of calcium‐dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci USA 1994; 91: 5212–5216
  • Arngrimsson R, Hayward C, Nadaud S, Baldursdottir A, Walker J J, Liston W A, Bjarnadottir R I, Brock D J, Geirsson R T, Connor J M, Soubrier F. Evidence for a familial pregnancy‐induced hypertension locus in the eNOS‐gene region. Am J Hum Genet 1997; 61: 354–362
  • Lewis I, Lachmeijer G, Downing S, Dekker G, Glazebrook C, Clayton D, Morris N H, O'Shaughnessy K M. Failure to detect linkage of preeeclampsia to the region of the NOS3 locus on chromosome 7q (letter). Am J Hum Genet 1999; 64: 310–313
  • Tempfer C B, Dorman K, Deter R L, O'Brien W E, Gregg A R. An endothelial nitric oxide synthase gene polymorphism is associated with preeclampsia. Hypertens Pregnancy 2001; 20(1)107–118

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.