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Research Article

IMPROVED SEMLIKI FOREST VIRUS VECTORS FOR RECEPTOR RESEARCH AND GENE THERAPY

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Pages 55-70 | Published online: 28 Feb 2001

REFERENCES

  • Liljeström P., Garoff H. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 1991; 9: 1356–1361
  • Xiong C., Levis R., Shen P., Schlesinger S., Rice C. M., Huang H. V. Sindbis virus: an efficient broad host range vector for gene expression in animal cells. Science 1989; 243: 1188–1191
  • Hahn C. S., Hahn Y. S., Braciale T. J., Rice C. M. Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc. Natl. Acad. Sci. USA 1992; 2679–2683
  • Lundstrom K., Pralong W., Martinou J.-C. Anti-apoptotic effect of bcl–2 overexpression in RIN cells infected with Semliki Forest virus. Apoptosis 1997; 2: 189–191
  • Berglund P., Tubulekas I., Liljeström P. Alphaviruses as vectors for gene delivery. Trends Biotechnol. 1996; 14: 1301–1334
  • Lundstrom K. Alphaviruses as tools in neurobiology and gene therapy. J. Receptor Signal Transduction Res. 1999; 19: 673–686
  • Ulmanen I., Peränen J., Tenhunen J., Tilgmann C., Karhunen T., Panula P., Bernasconi L., Aubry J.-P., Lundstrom K. Expression and intracellular localization of catechol-o-methyltransferase in transfected mammalian cells. Eur. J. Biochem. 1997; 243: 452–459
  • Scheer A., Bjorklov K., Cotecchia S., Lundstrom K. Expression of the α1b-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest virus expression system. J. Receptor Signal Transduction Res. 1999; 19: 369–378
  • Blasey H., Lundstrom K., Tate S., Bernard A. R. Recombinant protein production using Semliki Forest virus expression system. Cytotechnology 1997; 24: 65–72
  • Levis R., Schlesinger S., Huang H. V. The promoter for Sindbis virus RNA-dependent subgenomic RNA transcription. J. Virol. 1990; 64: 1726–1733
  • Raju R., Huang H. V. Analysis of Sindbis virus promoter recognitionin vivo, using novel vectors with two subgenomic mRNA promoters. J. Virol. 1991; 65: 2501–2510
  • Lundstrom K., Schweitzer C., Richards J. G., Ehrengruber M. U., Jenck F., Mumardt C. Semliki Forest virus vectors for in vitro and in vivo applications. Gene Ther. Mol. Biol. 1999; 4: 23–31
  • Lundstrom K., Rotmann D., Hermann D., Schneider E. M., Ehrengruber M. U. Novel mutant Semliki Forest virus vectors: gene expression and localization studies. Histochem. Cell Biol. 2001; 115: 83–91
  • Lundstrom K., Ahti H., Ulmanen I. In vitro mutagenesis of rat catechol-o-methyltransferase, M. R. El-Gewely. Site-directed mutagenesis and protein engineering. Elsevier Science Publishers, Amsterdam 1996; 119–122
  • Berglund P., Sjöberg M., Garoff H., Atkins G. J., Sheahan B. J., Liljeström P. Semliki Forest virus expression system: Production of conditionally infectious recombinant particles. Bio/Technology 1993; 11: 916–920
  • Lundstrom K., Mills A., Buell G., Allet E., Adami N., Liljeström P. High-level expression of the human neurokinin–1 receptor in mammalian cell lines using the Semliki Forest virus expression system. Eur. J. Biochem. 1994; 224: 917–921
  • Liljeström P., Garoff H. Expression of proteins using Semliki Forest virus vectors. Curr. Protocols Mol. Biol. 1991; 2: 16–22
  • Lundstrom K., Richards J. G., Pink J. R., Jenck F. Efficient in vivo expression of a reporter gene in rat brain after injection of recombinant replication– deficient Semliki Forest virus. Gene Ther. Mol. Biol. 1999; 3: 15–23
  • Ehrengruber M. U., Lundstrom K., Schweitzer C., Heuss C., Schlesinger S., Gähwiler B. H. Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures. Proc. Natl. Acad. Sci. USA 1999; 96: 7041–7046
  • Hahn Y. S., Strauss E. G., Strauss J. H. Mapping of RNA−temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins. J. Virol. 1989; 63: 3142–3150
  • Hahn Y. S., Grakoul A., Rice C. M., Strauss E. G., Strauss J. H. Mapping of RNA–temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4. J. Virol. 1989; 63: 1194–1202
  • Rikkonen M. Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2. Virology 1996; 218: 352–361
  • Boorsma M., Nieba L., Koller D., Bachmann M. F., Bailey J. E., Renner W. A. A temperature regulated replicon-based DNA expression system. Nat. Biotechnol. 2000; 18: 429–432
  • Perri S., Driver D. A., Gardner J. P., Sherrill S., Belli B. A., Dubensky T. W., Jr., Polo J. M. Replicon vectors derived from Sindbis virus and Semliki Forest virus that established persistent replication in host cells. J. Virol. 2000; 74: 9802–9807
  • Agapov E. V., Frolov I., Lindenbach B. D., Pragai B. M., Schlesinger S., Rice C. M. Noncytopathogenic Sindbis virus RNA vectors for heterologous gene expression. Proc. Natl. Acad. Sci. USA 1998; 95: 12989–12994
  • Tuittila M. T., Santagati M. G., Röyttä M., Määttä J. A., Hinkkanen A. E. Replicase complex genes of Semliki Forest virus confer lethal neurovirulence. J. Virol. 2000; 74: 4579–4589
  • Asselin-Paturel C., Lassau N., Guinebretiere J.-M., Zhang J., Gay F., Bex F., Hallez S., Leclere J., Peronneau P., Mami-Chouaib F., Chouaib S. Transfer of the murine interleukin–12 gene in vivo by a Semliki Forest virus vector induces tumor regression through inhibition of tumor blood vessel formation monitored by Doppler ultrasonography. Gene Ther. 1999; 6: 606–615
  • Murphy A.-M., Morris-Downes M. M., Sheahan B. J., Atkins G. J. Inhibition of human lung carcinoma cell growth by apoptosis induction using Semliki Forest virus recombinant particles. Gene Ther. 2000; 7: 1477–1482
  • Li K.-J., Garoff H. Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors. Proc. Natl. Acad. Sci. USA 1996; 93: 11658–11663
  • Wahlfors J. J., Xanthopoulus K. G., Morgan R. A. Semliki Forest virus-mediated production of retroviral vector RNA in retroviral packaging cells. Hum. Gene Ther. 1997; 8: 2031–2041
  • Lebedeva I., Fujita K., Nihrane A., Silver J. Infectious particles derived from Semliki Forest virus vectors encoding murine leukemia virus envelope. J. Virol. 1997; 71: 7061–7067

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