THE USE OF PHAGE DISPLAY IN THE STUDY OF RECEPTORS AND THEIR LIGANDS

REFERENCES

• Brown S. Engineered Iron oxide-Adhesion Mutants of the Escherichia coli Phage Lambda Receptor. Proc. Natl. Acad. Sci. USA 1992; 89: 8651–8655
   PubMed Web of Science ®Google Scholar
• Cull M. G., Miller J. F., Schatz P. J. Screening for Receptor Ligands Using Large Libraries of Peptides Linked to the C Terminus of the Lac Repressor. Proc. Natl. Acad. Sci. USA 1992; 89: 1865–1869
   PubMed Web of Science ®Google Scholar
• Mattheakis L. C., Bhatt R. R., Dower W. J. An In Vitro Polysome Display System for Identifying Ligands from Very Large Peptide Libraries. Proc. Natl. Acad. Sci. USA 1994; 91: 9022–9026
   PubMed Web of Science ®Google Scholar
• Maruyama I. N., Maruyama H. I., Brenner S. Lambda Foo: a Lambda Phage Vector for the Expression of Foreign Proteins. Proc. Natl. Acad. Sci. USA 1994; 91: 8273–8277
   PubMed Web of Science ®Google Scholar
• Houshmand H., Froman G., Magnusson G. Use of Bacteriophage T7 Displayed Peptides for Determination of Monoclonal Antibody Specificity and Biosensor Analysis of the Binding Reaction. Anal. Biochem. 1999; 268: 363–370
   PubMed Web of Science ®Google Scholar
• Smith G. P. Filamentous Fusion Phage: Novel Expression Vectors that Display Cloned Antigens on the Virion Surface. Science 1985; 228: 1315–1317
   PubMed Web of Science ®Google Scholar
• Bass S., Greene R., Wells J. A. Hormone Phage: an Enrichment Method for Variant Proteins with Altered Binding Properties. Proteins 1990; 8: 309–314
   PubMed Web of Science ®Google Scholar
• Garrard L. J., Yang M., O'Connell M. P., Kelley R. F., Henner D. J. Fab Assembly and Enrichment in a Monovalent Phage Display System. Biotechnology 1991; 9: 1373–1377
   PubMedGoogle Scholar
• Hoogenboom H. R., Griffiths A. D., Johnson K. S., Chiswell D. J., Hudson P., Winter G. Multi-Subunit Proteins on the Surface of Filamentous Phage: Methodologies for Displaying Antibody (Fab) Heavy and Light Chains. Nucleic Acids Res. 1991; 19: 4133–4137
   PubMed Web of Science ®Google Scholar
• Griffiths A. D., Malmqvist M., Marks J. D., Bye J. M., Embleton M. J., McCafferty J., Baier M., Holliger K. P., Gorick B. D., Hughes-Jones N. C. Human Anti-Self Antibodies with High Specificity from Phage Display Libraries. Embo J. 1993; 12: 725–734, et al.
   PubMed Web of Science ®Google Scholar
• Rakonjac J., Jovanovic G., Model P. Filamentous Phage Infection-Mediated Gene Expression: Construction and Propagation of the gIII Deletion Mutant Helper Phage R408d3. Gene 1997; 198: 99–103
   PubMed Web of Science ®Google Scholar
• Scott J. K., Smith G. P. Searching for Peptide Ligands with an Epitope Library. Science 1990; 249: 386–390
   PubMed Web of Science ®Google Scholar
• Devlin J. J., Panganiban L. C., Devlin P. E. Random Peptide Libraries: a Source of Specific Protein Binding Molecules. Science 1990; 249: 404–406
   PubMed Web of Science ®Google Scholar
• Cortese R., Monaci P., Luzzago A., Santini C., Bartoli F., Cortese I., Fortugno P., Galfre G., Nicosia A., Felici F. Selection of Biologically Active Peptides by Phage Display of Random Peptide Libraries. Curr. Opin. Biotechnol. 1996; 7: 616–621
   PubMed Web of Science ®Google Scholar
• Lowman H. B. Bacteriophage Display and Discovery of Peptide Leads for Drug Development. Annu. Rev. Biophys. Biomol. Struct. 1997; 26: 401–424
   PubMedGoogle Scholar
• Cesareni G., Castagnoli L., Cestra G. Phage Displayed Peptide Libraries. Comb. Chem. High Throughput Screen. 1999; 2: 1–17
   PubMed Web of Science ®Google Scholar
• O'Neil K. T., Hoess R. H., Jackson S. A., Ramachandran N. S., Mousa S. A., DeGrado W. F. Identification of Novel Peptide Antagonists for GPIIb/IIIa from a Conformationally Constrained Phage Peptide Library. Proteins 1992; 14: 509–515
   PubMed Web of Science ®Google Scholar
• Ladner R. C. Constrained Peptides as Binding Entities. Trends Biotechnol. 1995; 13: 426–430
   PubMed Web of Science ®Google Scholar
• Giebel L. B., Cass R. T., Milligan D. L., Young D. C., Arze R., Johnson C. R. Screening of Cyclic Peptide Phage Libraries Identifies Ligands that Bind Streptavidin with High Affinities. Biochemistry 1995; 34: 15430–15435
   PubMed Web of Science ®Google Scholar
• Smith G. Patch Engineering: a General Approach for Creating Proteins that Have New Binding Activities. Trends Biochem. Sci. 1998; 23: 457–460
   PubMed Web of Science ®Google Scholar
• Ladner R. C., Ley A. C. Novel Frameworks as a Source of High-Affinity Ligands. Curr. Opin. Biotechnol. 2001; 12: 406–410
   PubMed Web of Science ®Google Scholar
• Noren K. A., Noren C. J. Construction of High-Complexity Combinatorial Phage Display Peptide Libraries. Methods 2001; 23: 169–178
   PubMed Web of Science ®Google Scholar
• Kay B. K., Kasanov J., Yamabhai M. Screening Phage-Displayed Combinatorial Peptide Libraries. Methods 2001; 24: 240–246
   PubMed Web of Science ®Google Scholar
• Sidhu S. S. Phage Display in Pharmaceutical Biotechnology. Curr. Opin. Biotechnol. 2000; 11: 610–616
   PubMed Web of Science ®Google Scholar
• McCafferty J., Griffiths A. D., Winter G., Chiswell D. J. Phage Antibodies: Filamentous Phage Displaying Antibody Variable Domains. Nature 1990; 348: 552–554
   PubMed Web of Science ®Google Scholar
• Barbas C. F., III, Kang A. S., Lerner R. A., Benkovic S. J. Assembly of Combinatorial Antibody Libraries on Phage Surfaces: the Gene III site. Proc. Natl. Acad. Sci. USA 1991; 88: 7978–7982
   PubMed Web of Science ®Google Scholar
• Clackson T., Hoogenboom H. R., Griffiths A. D., Winter G. Making Antibody Fragments Using Phage Display Libraries. Nature 1991; 352: 624–628
   PubMed Web of Science ®Google Scholar
• Hoogenboom H. R., Winter G. By-Passing Immunisation. Human Antibodies from Synthetic Repertoires of Germline VH Gene Segments Rearranged In Vitro. J. Mol. Biol. 1992; 227: 381–388
   PubMed Web of Science ®Google Scholar
• Barbas C. F., 3rd, Bain J. D., Hoekstra D. M., Lerner R. A. Semisynthetic Combinatorial Antibody Libraries: a Chemical Solution to the Diversity Problem. Proc. Natl. Acad. Sci. USA 1992; 89: 4457–4461
   PubMed Web of Science ®Google Scholar
• Griffiths A. D., Duncan A. R. Strategies for Selection of Antibodies by Phage Display. Curr. Opin. Biotechnol. 1998; 9: 102–108
   PubMed Web of Science ®Google Scholar
• Hoogenboom H. R., de Bruine A. P., Hufton S. E., Hoet R. M., Arends J. W., Roovers R. C. Antibody Phage Display Technology and its Applications. Immunotechnology 1998; 4: 1–20
   PubMedGoogle Scholar
• Wilson S., Bergsma D. J., Chambers J. K., Muir A. I., Fantom K. G., Ellis C., Murdock P. R., Herrity N. C., Stadel J. M. Orphan G-Protein-Coupled Receptors: the Next Generation of Drug Targets? Br. J. Pharmacol. 1998; 125: 1387–1392
   Google Scholar
• Jespers L. S., Messens J. H., De Keyser A., Eeckhout D., van den Brande I., Gansemans Y. G., Lauwereys M. J., Vlasuk G. P., Stanssens P. E. Surface Expression and Ligand-Based Selection of cDNAs Fused to Filamentous Phage Gene VI. Biotechnology 1995; 13: 378–382
   PubMedGoogle Scholar
• Hufton S. E., Moerkerk P. T., Meulemans E. V., de Bruine A., Arends J. W., Hoogenboom H. R. Phage Display of cDNA Repertoires: the pVI Display System and its Applications for the Selection of Immunogenic Ligands. J. Immunol. Meth. 1999; 231: 39–51
   PubMed Web of Science ®Google Scholar
• Fuh G., Pisabarro M. T., Li Y., Quan C., Lasky L. A., Sidhu S. S. Analysis of PDZ Domain-Ligand Interactions Using Carboxyl-Terminal Phage Display. J. Biol. Chem. 2000; 275: 21486–21491
   Google Scholar
• Fuh G., Sidhu S. S. Efficient Phage Display of Polypeptides Fused to the Carboxy-Terminus of the M13 Gene-3 Minor Coat Protein. FEBS Lett. 2000; 480: 231–234
   PubMed Web of Science ®Google Scholar
• Crameri R., Suter M. Display of Biologically Active Proteins on the Surface of Filamentous Phages: a cDNA Cloning System for Selection of Functional Gene Products Linked to the Genetic Information Responsible for their Production. Gene 1993; 137: 69–75
   PubMed Web of Science ®Google Scholar
• Santi E., Capone S., Mennuni C., Lahm A., Tramontano A., Luzzago A., Nicosia A. Bacteriophage Lambda Display of Complex cDNA Libraries: a New Approach to Functional Genomics. J. Mol. Biol. 2000; 296: 497–508
   PubMed Web of Science ®Google Scholar
• Cain S. A., Ratcliffe C. F., Williams D. M., Harris V., Monk P. N. Analysis of Receptor/Ligand Interactions Using Whole-Molecule Randomly-Mutated Ligand Libraries. J. Immunol. Meth. 2000; 245: 139–145
   PubMed Web of Science ®Google Scholar
• Low N. M., Holliger P. H., Winter G. Mimicking Somatic Hypermutation: Affinity Maturation of Antibodies Displayed on Bacteriophage Using a Bacterial Mutator Strain. J. Mol. Biol. 1996; 260: 359–368
   PubMed Web of Science ®Google Scholar
• Cabibbo A., Sporeno E., Toniatti C., Altamura S., Savino R., Paonessa G., Ciliberto G. Monovalent Phage Display of Human Interleukin (hIL)-6: Selection of Superbinder Variants from a Complex Molecular Repertoire in the hIL-6 D- Helix. Gene 1995; 167: 41–47
   PubMed Web of Science ®Google Scholar
• Heller T., Hennecke M., Baumann U., Gessner J. E., zu Vilsendorf A. M., Baensch M., Boulay F., Kola A., Klos A., Bautsch W., Kohl J. Selection of a C5a Receptor Antagonist from Phage Libraries Attenuating the Inflammatory Response in Immune Complex Disease and Ischemia/Reperfusion Injury. J. Immunol. 1999; 163: 985–994
   PubMed Web of Science ®Google Scholar
• Stemmer W. P. Rapid Evolution of a Protein In Vitro by DNA Shuffling. Nature 1994; 370: 389–391
   PubMed Web of Science ®Google Scholar
• Langman R. E., Cohn M. The E-T (Elephant-Tadpole) Paradox Necessitates the Concept of a Unit of B-Cell Function: the Protection. Mol. Immunol. 1987; 24: 675–697
   PubMed Web of Science ®Google Scholar
• Nissim A., Hoogenboom H. R., Tomlinson I. M., Flynn G., Midgley C., Lane D., Winter G. Antibody Fragments from a ‘Single Pot’ Phage Display Library as Immunochemical Reagents. Embo. J. 1994; 13: 692–698
   PubMed Web of Science ®Google Scholar
• Perelson A. S. Immune Network Theory. Immunol. Rev. 1989; 110: 5–36
   PubMed Web of Science ®Google Scholar
• Griffiths A. D., Williams S. C., Hartley O., Tomlinson I. M., Waterhouse P., Crosby W. L., Kontermann R. E., Jones P. T., Low N. M., Allison T. J. Isolation of High Affinity Human Antibodies Directly from Large Synthetic Repertoires. Embo. J. 1994; 13: 3245–3260, et al.
   PubMed Web of Science ®Google Scholar
• Fisch I., Kontermann R. E., Finnern R., Hartley O., Soler-Gonzalez A. S., Griffiths A. D., Winter G. A Strategy of Exon Shuffling for Making Large Peptide Repertoires Displayed on Filamentous Bacteriophage. Proc. Natl. Acad. Sci. USA 1996; 93: 7761–7766
   PubMed Web of Science ®Google Scholar
• Sidhu S. S., Lowman H. B., Cunningham B. C., Wells J. A. Phage Display for Selection of Novel Binding Peptides. Methods Enzymol. 2000; 328: 333–363
   PubMed Web of Science ®Google Scholar
• Hawkins R. E., Russell S. J., Winter G. Selection of Phage Antibodies by Binding Affinity. Mimicking Affinity Maturation. J. Mol. Biol. 1992; 226: 889–896
   PubMed Web of Science ®Google Scholar
• Marks J. D., Griffiths A. D., Malmqvist M., Clackson T. P., Bye J. M., Winter G. By-Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling. Biotechnology 1992; 10: 779–783
   PubMed Web of Science ®Google Scholar
• Crameri A., Cwirla S., Stemmer W. P. Construction and Evolution of Antibody-Phage Libraries by DNA Shuffling. Nat. Med. 1996; 2: 100–102
   Google Scholar
• Glaser S. M., Yelton D. E., Huse W. D. Antibody Engineering by Codon-Based Mutagenesis in a Filamentous Phage Vector System. J. Immunol. 1992; 149: 3903–3913
   PubMed Web of Science ®Google Scholar
• Virnekas B., Ge L., Pluckthun A., Schneider K. C., Wellnhofer G., Moroney S. E. Trinucleotide Phosphoramidites: Ideal Reagents for the Synthesis of Mixed Oligonucleotides for Random Mutagenesis. Nucleic Acids Res. 1994; 22: 5600–5607
   PubMed Web of Science ®Google Scholar
• Jackson J. R., Sathe G., Rosenberg M., Sweet R. In Vitro Antibody Maturation. Improvement of a High Affinity, Neutralizing Antibody Against IL-1 Beta. J. Immunol. 1995; 154: 3310–3319
   PubMed Web of Science ®Google Scholar
• Schier R., Bye J., Apell G., McCall A., Adams G. P., Malmqvist M., Weiner L. M., Marks J. D. Isolation of High-Affinity Monomeric Human Anti-c-erbB-2 Single Chain Fv Using Affinity-Driven Selection. J. Mol. Biol. 1996; 255: 28–43
   PubMed Web of Science ®Google Scholar
• Szardenings M., Tornroth S., Mutulis F., Muceniece R., Keinanen K., Kuusinen A., Wikberg J. E. Phage Display Selection on Whole Cells Yields a Peptide Specific for Melanocortin Receptor 1. J. Biol. Chem. 1997; 272: 27943–27948
   PubMed Web of Science ®Google Scholar
• Gray P. W., Barrett K., Chantry D., Turner M., Feldmann M. Cloning of Human Tumor Necrosis Factor (TNF) Receptor cDNA and Expression of Recombinant Soluble TNF-Binding Protein. Proc. Natl. Acad. Sci. USA 1990; 87: 7380–7384
   PubMed Web of Science ®Google Scholar
• Byrn R. A., Mordenti J., Lucas C., Smith D., Marsters S. A., Johnson J. S., Cossum P., Chamow S. M., Wurm F. M., Gregory T. Biological Properties of a CD4 Immunoadhesin. Nature 1990; 344: 667–670, et al.
   PubMed Web of Science ®Google Scholar
• Kallen K. J., Grotzinger J., Rose-John S. New Perspectives on the Design of Cytokines and Growth Factors. Trends Biotechnol. 2000; 18: 455–461
   PubMed Web of Science ®Google Scholar
• Li B., Fuh G., Meng G., Xin X., Gerritsen M. E., Cunningham B., de Vos A. M. Receptor-Selective Variants of Human Vascular Endothelial Growth Factor. Generation and characterization. J. Biol. Chem. 2000; 275: 29823–29828
   PubMed Web of Science ®Google Scholar
• Saggio I., Gloaguen I., Poiana G., Laufer R. CNTF variants with Increased Biological Potency and Receptor Selectivity Define a Functional Site of Receptor Interaction. Embo. J. 1995; 14: 3045–3054
   PubMed Web of Science ®Google Scholar
• Chang C. C., Chen T. T., Cox B. W., Dawes G. N., Stemmer W. P., Punnonen J., Patten P. A. Evolution of a Cytokine Using DNA Family Shuffling. Nat. Biotechnol. 1999; 17: 793–797
   PubMed Web of Science ®Google Scholar
• Wrighton N. C., Farrell F. X., Chang R., Kashyap A. K., Barbone F. P., Mulcahy L. S., Johnson D. L., Barrett R. W., Jolliffe L. K., Dower W. J. Small Peptides as Potent Mimetics of the Protein Hormone Erythropoietin. Science 1996; 273: 458–464
   PubMed Web of Science ®Google Scholar
• Cwirla S. E., Balasubramanian P., Duffin D. J., Wagstrom C. R., Gates C. M., Singer S. C., Davis A. M., Tansik R. L., Mattheakis L. C., Boytos C. M., Schatz P. J., Baccanari D. P., Wrighton N. C., Barrett R. W., Dower W. J. Peptide Agonist of the Thrombopoietin Receptor as Potent as the Natural Cytokine. Science 1997; 276: 1696–1699
   PubMed Web of Science ®Google Scholar
• Ballinger M. D., Shyamala V., Forrest L. D., Deuter-Reinhard M., Doyle L. V., Wang J. X., Panganiban-Lustan L., Stratton J. R., Apell G., Winter J. A., Doyle M. V., Rosenberg S., Kavanaugh W. M. Semirational Design of a Potent, Artificial Agonist of Fibroblast Growth Factor Receptors. Nat. Biotechnol. 1999; 17: 1199–1204
   PubMed Web of Science ®Google Scholar
• Tate C. G. Overexpression of Mammalian Integral Membrane Proteins for Structural Studies. FEBS Lett. 2001; 504: 94–98
   PubMed Web of Science ®Google Scholar
• Lundstrom K., Schweitzer C., Rotmann D., Hermann D., Schneider E. M., Ehrengruber M. U. Semliki Forest Virus Vectors: Efficient Vehicles for In Vitro and In Vivo Gene Delivery. FEBS Lett. 2001; 504: 99–103
   PubMed Web of Science ®Google Scholar
• Mirzabekov T., Kontos H., Farzan M., Marasco W., Sodroski J. Paramagnetic Proteoliposomes Containing a Pure, Native, and Oriented Seven-Transmembrane Segment Protein, CCR5. Nat. Biotechnol. 2000; 18: 649–654
   PubMed Web of Science ®Google Scholar
• Babcock G. J., Mirzabekov T., Wojtowicz W., Sodroski J. Ligand Binding Characteristics of CXCR4 Incorporated into Paramagnetic Proteoliosomes. J. Biol. Chem. 2001; 276: 38433–38440
   PubMed Web of Science ®Google Scholar
• Jespersen L. K., Kuusinen A., Orellana A., Keinanen K., Engberg J. Use of Proteoliposomes to Generate Phage Antibodies Against Native AMPA Receptor. Eur. J. Biochem. 2000; 267: 1382–1389
   PubMedGoogle Scholar
• Souriau C., Fort P., Roux P., Hartley O., Lefranc M. P., Weill M. A Simple Luciferase Assay for Signal Transduction Activity Detection of Epidermal Growth Factor Displayed on Phage. Nucleic Acids Res. 1997; 25: 1585–1590
   PubMed Web of Science ®Google Scholar
• Hennecke M., Kola A., Baensch M., Wrede A., Klos A., Bautsch W., Kohl J. A selection System to Study C5a-C5a-Receptor Interactions: Phage Display of a Novel C5a Anaphylatoxin, Fos-C5aAla27. Gene 1997; 184: 263–272
   PubMed Web of Science ®Google Scholar
• Hennecke M., Otto A., Baensch M., Kola A., Bautsch W., Klos A., Kohl J. A Detailed Analysis of the C5a Anaphylatoxin Effector Domain: Selection of C5a Phage Libraries on Differentiated U937 Cells. Eur. J. Biochem. 1998; 252: 36–44
   PubMedGoogle Scholar
• Marks J. D., Ouwehand W. H., Bye J. M., Finnern R., Gorick B. D., Voak D., Thorpe S. J., Hughes-Jones N. C., Winter G. Human Antibody Fragments Specific for Human Blood Group Antigens from a Phage Display Library. Biotechnology 1993; 11: 1145–1149
   PubMed Web of Science ®Google Scholar
• Cai X., Garen A. Anti-Melanoma Antibodies from Melanoma Patients Immunized with Genetically Modified Autologous Tumor Cells: Selection of Specific Antibodies from Single-Chain Fv Fusion Phage Libraries. Proc. Natl. Acad. Sci. USA 1995; 92: 6537–6541
   PubMed Web of Science ®Google Scholar
• Doorbar J., Winter G. Isolation of a Peptide Antagonist to the Thrombin Receptor Using Phage Display. J. Mol. Biol. 1994; 244: 361–369
   PubMed Web of Science ®Google Scholar
• de Kruif J., Terstappen L., Boel E., Logtenberg T. Rapid Selection of Cell Subpopulation-Specific Human Monoclonal Antibodies from a Synthetic Phage Antibody Library. Proc. Natl. Acad. Sci. USA 1995; 92: 3938–3942
   PubMed Web of Science ®Google Scholar
• Siegel D. L., Chang T. Y., Russell S. L., Bunya V. Y. Isolation of Cell Surface-Specific Human Monoclonal Antibodies Using Phage Display and Magnetically-Activated Cell Sorting: Applications in Immunohematology. J. Immunol. Meth. 1997; 206: 73–85
   PubMed Web of Science ®Google Scholar
• Meulemans E. V., Slobbe R., Wasterval P., Ramaekers F. C., van Eys G. J. Selection of Phage-Displayed Antibodies Specific for a Cytoskeletal Antigen by Competitive Elution with a Monoclonal Antibody. J. Mol. Biol. 1994; 244: 353–360
   PubMedGoogle Scholar
• van Ewijk W., de Kruif J., Germeraad W. T., Berendes P., Ropke C., Platenburg P. P., Logtenberg T. Subtractive Isolation of Phage-Displayed Single-Chain Antibodies to Thymic Stromal Cells by Using Intact Thymic Fragments. Proc. Natl. Acad. Sci. USA 1997; 94: 3903–3908
   PubMed Web of Science ®Google Scholar
• Lekkerkerker A., Logtenberg T. Phage Antibodies Against Human Dendritic Cell Subpopulations Obtained by Flow Cytometry-Based Selection on Freshly Isolated Cells. J. Immunol. Meth. 1999; 231: 53–63
   PubMed Web of Science ®Google Scholar
• Kolonin M., Pasqualini R., Arap W. Molecular Addresses in Blood Vessels as Targets for Therapy. Curr. Opin. Chem. Biol. 2001; 5: 308–313
   PubMed Web of Science ®Google Scholar
• Osbourn J. K., Earnshaw J. C., Johnson K. S., Parmentier M., Timmermans V., McCafferty J. Directed Selection of MIP-1 Alpha Neutralizing CCR5 Antibodies from a Phage Display Human Antibody Library. Nat. Biotechnol. 1998; 16: 778–781
   PubMed Web of Science ®Google Scholar
• Osbourn J. K., Derbyshire E. J., Vaughan T. J., Field A. W., Johnson K. S. Pathfinder Selection: In Situ Isolation of Novel Antibodies. Immunotechnology 1998; 3: 293–302
   PubMedGoogle Scholar
• Pearce K. H., Jr., Cunningham B. C., Fuh G., Teeri T., Wells J. A. Growth Hormone Binding Affinity for its Receptor Surpasses the Requirements for Cellular Activity. Biochemistry 1999; 38: 81–89
   PubMed Web of Science ®Google Scholar
• Zaccolo M., Griffiths A. P., Prospero T. D., Winter G., Gherardi E. Dimerization of Fab Fragments Enables Ready Screening of Phage Antibodies that Affect Hepatocyte Growth Factor/Scatter Factor Activity on Target Cells. Eur. J. Immunol. 1997; 27: 618–623
   PubMed Web of Science ®Google Scholar
• Xie M. H., Yuan J., Adams C., Gurney A. Direct Demonstration of MuSK Involvement in Acetylcholine Receptor Clustering Through Identification of Agonist ScFv. Nat. Biotechnol. 1997; 15: 768–771
   PubMed Web of Science ®Google Scholar
• Rousch M., Lutgerink J. T., Coote J., de Bruine A., Arends J. W., Hoogenboom H. R. Somatostatin Displayed on Filamentous Phage as a Receptor-Specific Agonist. Br. J. Pharmacol. 1998; 125: 5–16
   PubMed Web of Science ®Google Scholar
• Hart S. L., Knight A. M., Harbottle R. P., Mistry A., Hunger H. D., Cutler D. F., Williamson R., Coutelle C. Cell Binding and Internalization by Filamentous Phage Displaying a Cyclic Arg-Gly-Asp-Containing Peptide. J. Biol. Chem. 1994; 269: 12468–12474
   PubMed Web of Science ®Google Scholar
• Barry M. A., Dower W. J., Johnston S. A. Toward Cell-Targeting Gene Therapy Vectors: Selection of Cell-Binding Peptides from Random Peptide-Presenting Phage Libraries. Nat. Med. 1996; 2: 299–305
   PubMed Web of Science ®Google Scholar
• Ivanenkov V. V., Felici F., Menon A. G. Targeted Delivery of Multivalent Phage Display Vectors into Mammalian Cells. Biochim. Biophys. Acta 1999; 1448: 463–472
   PubMed Web of Science ®Google Scholar
• Poul M. A., Becerril B., Nielsen U. B., Morisson P., Marks J. D. Selection of Tumor-Specific Internalizing Human Antibodies from Phage Libraries. J. Mol. Biol. 2000; 301: 1149–1161
   PubMed Web of Science ®Google Scholar
• Kassner P. D., Burg M. A., Baird A., Larocca D. Genetic Selection of Phage Engineered for Receptor-Mediated Gene Transfer to Mammalian Cells. Biochem. Biophys. Res. Commun. 1999; 264: 921–928
   PubMed Web of Science ®Google Scholar
• Poul M. A., Marks J. D. Targeted Gene Delivery to Mammalian Cells by Filamentous Bacteriophage. J. Mol. Biol. 1999; 288: 203–211
   PubMed Web of Science ®Google Scholar
• Larocca D., Kassner P. D., Witte A., Ladner R. C., Pierce G. F., Baird A. Gene Transfer to Mammalian Cells Using Genetically Targeted Filamentous Bacterio-phage. Faseb J. 1999; 13: 727–734
   PubMed Web of Science ®Google Scholar
• Larocca D., Baird A. Receptor-Mediated Gene Transfer by Phage-Display Vectors: Applications in Functional Genomics and Gene Therapy. Drug Discov. Today 2001; 6: 793–801
   PubMed Web of Science ®Google Scholar
• Pini A., Viti F., Santucci A., Carnemolla B., Zardi L., Neri P., Neri D. Design and Use of a Phage Display Library. Human Antibodies with Subnanomolar Affinity Against a Marker Of Angiogenesis Eluted from a Two-Dimensional Gel. J. Biol. Chem. 1998; 273: 21769–21776
   PubMed Web of Science ®Google Scholar
• Williams C. Biotechnology Match Making: Screening Orphan Ligands and Receptors. Curr. Opin. Biotechnol. 2000; 11: 42–46
   PubMed Web of Science ®Google Scholar
• Stoica G. E., Kuo A., Aigner A., Sunitha I., Souttou B., Malerczyk C., Caughey D. J., Wen D., Karavanov A., Riegel A. T., Wellstein A. Identification of Anaplastic Lymphoma Kinase as a Receptor for the Growth Factor Pleiotrophin. J. Biol. Chem. 2001; 276: 16772–16779
   PubMed Web of Science ®Google Scholar
• Cunningham B. C., Wells J. A. Minimized Proteins. Curr. Opin. Struct. Biol. 1997; 7: 457–462
   PubMed Web of Science ®Google Scholar