Engineered Yeasts as Reporter Systems for Odorant Detection

References

• Zhao H., Ivic L., Otaki J. M., Hashimoto M., Mikoshiba K., Firestein S. Functional expression of a mammalian odorant receptor. Science 1998; 279: 237–242, 250:121–123
   PubMed Web of Science ®Google Scholar
• Krautwurst D., Yau K. W., Reed R. R. Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 1998; 95: 917–926
   PubMed Web of Science ®Google Scholar
• King K., Dohlman H. G., Thorner J., Caron M. G., Lefkowitz R. J. Control of yeast mating signal transduction by a mammalian beta2‐adrenergic receptor and Gs alpha subunit. Science 1990; 250: 121–123
   PubMedGoogle Scholar
• Price L. A., Kajkowski E. M., Hadcock J. R., Ozenberger B. A., Pausch M. H. Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Mol Cell Biol 1995; 15: 6188–6195
   PubMed Web of Science ®Google Scholar
• Price L. A., Strnad J., Pausch M. H., Hadcock J. R. Pharmacological characterization of the rat A2a adenosine receptor functionally coupled to the yeast pheromone response pathway. Mol Pharmacol 1996; 50: 829–837
   PubMedGoogle Scholar
• Pausch M. H. G‐protein‐coupled receptors in Saccharomyces cerevisiae: high‐throughput screening assays for drug discovery. TIBTech 1997; 15: 487–494
   PubMedGoogle Scholar
• Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 1991; 65: 175–187
   PubMed Web of Science ®Google Scholar
• Miyajima I., Nakafuku M., Nakayama N., Brenner C., Miyajima A., Kaibuchi K., Ken‐ichi A., Kaziro Y., Matsumoto K. GPA1, a haploid‐specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction. Cell 1987; 50: 1011–1019
   PubMed Web of Science ®Google Scholar
• Kang Y. S., Kane J., Kurjan J., Stadel J. M., Tipper D. J. Effects of expression of mammalian G alpha and hybrid mammalian‐yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol 1990; 10: 2582–2590
   PubMed Web of Science ®Google Scholar
• Crowe M. L., Perry B. N., Connerton I. F. Golf complements a Gpa1 null mutation in Saccharomyces cerevisiae and functionally couples to the Ste2 pheromone receptor. J Recept Signal Tranduct Res 2000; 20: 61–73
   Web of Science ®Google Scholar
• Kajkowski E. M., Price L. A., Pausch M. H., Young K. H., Ozenberger B. A. Investigation of growth hormone releasing hormone receptor structure and activity using yeast expression technologies. J Recept Signal Transduct Res 1997; 17: 293–303
   PubMed Web of Science ®Google Scholar
• Gritz L., Davies J. Plasmid‐encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene 1983; 25: 179–188
   PubMed Web of Science ®Google Scholar
• Stevenson B. J., Rhodes N., Errede B., Sprague G. F., Jr. Constitutive mutants of the proteine kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev 1992; 6: 1293–1304
   PubMed Web of Science ®Google Scholar
• Schultz L. D., Hofmann K. J., Mylin L. M., Montgomery D. L., Ellis R. W., Hopper J. E. Regulated overproduction of the GAL4 gene product greatly increases expression from galactose‐inducible promoters on multi‐copy vectors in yeast. Gene 1987; 61: 123–133
   PubMedGoogle Scholar
• Yocum R. R., Hanley S., West R., Jr., Ptashne M. Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1‐GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol 1984; 4: 1985–1998
   PubMed Web of Science ®Google Scholar
• Jones D. T., Reed R. R. Golf: an olfactory neuron specific‐G protein involved in odorant signal transduction. Science 1989; 244: 790–795
   PubMed Web of Science ®Google Scholar
• Schiestl R. H., Manivasakam P., Woods R. A., Gietz R. D. Methods 1993; 5: 79–85
   Google Scholar
• Connerton I. F. Expression of membrane proteins in yeast. Membrane Protein Expression Systems—A User's Guide, G. W. Gould. Portland Press, London 1994
   Google Scholar
• Wiley J. Preparation of yeast RNA. Current Protocols in Molecular Biology, J. Wiley, New York 1993, Supplement 23, Unit 13.12
   Google Scholar
• Hansen M. K., Tams J. W., Fahrenkrug J., Pedersen P. A. Functional expression of rat VPAC1 receptor in Saccharomyces cerevisiae. Receptors Channels 1999; 6: 271–281
   Google Scholar
• Brown A. J., Dyos S. L., Whiteway J. H., White J. H.M., Watson M. A.E.A., Marzioch M., Clare J. J., Cousens D. J., Paddon C., Plumpton C., Romanos M. A., Dowell S. J. Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha‐subunit chimeras. Yeast 2000; 16: 11–22
   Google Scholar
• Kajiya K., Inaki K., Tanaka M., Haga T., Kataoka H., Touhara K. Molecular bases of odor discrimination: reconstitution of olfactory receptors that recognize overlapping sets of odorants. J Neurosci 2001; 21(16)6018–6025
   Google Scholar
• Levasseur G., Persuy M. A., Grebert D., Remy J. J., Salesse R., Pajot‐Augy E. Ligand‐specific dose‐response of heterologously expressed olfactory receptors. Eur J Biochem 2003; 270: 2905–2912
   Google Scholar
• Lagane B., Gaibelet G., Meilhoc E., Masson J. M., Cezanne L., Lopez A. Role of sterols in modulating the human mu‐opiod receptor function in Saccharomyces cerevisiae. J Biol Chem 2000; 275: 33197–33200
   PubMedGoogle Scholar
• Singer M. S. Analysis of the molecular basis for octanal interactions in the expressed I7 olfactory receptor. Chem Senses 2000; 25: 155–165
   PubMed Web of Science ®Google Scholar