135
Views
15
CrossRef citations to date
0
Altmetric
Research Article

A Computer‐Based Model for the Regulation of Mitogen Activated Protein Kinase (MAPK) Activation

&
Pages 197-209 | Published online: 10 Jul 2003

References

  • Canals F. Signal transmission by epidermal growth factor receptor: coincidence of activation and dimerization. Biochemistry 1992; 31: 4493–4501
  • Sherrill J. M., Kyte J. Activation of epidermal growth factor receptor by epidermal growth factor. Biochemistry 1996; 35: 5705–5718
  • Sorkin A., McClure M., Huang F., Carter R. Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Curr Biol 2000; 10: 1395–1398
  • Chang L., Karin M. Mammalian MAP kinase signaling cascades. Nature 2001; 410: 37–40
  • Weston C. R., Davis R. J. The JNK signal transduction pathway. Curr Opin Genet Dev 2002; 12: 14–21
  • Uchida M., Kirito K., Shimizu R., Miura Y., Ozawa K., Komatsu N. A functional role of mitogen‐activated protein kinases, Erk1 and Erk2, in the differentiation of a human leukemia cell line, UT‐7/GM: a possible key factor for cell fate determination toward erythroid and megakaryocytic lineages. Int J Hematol 2001; 73: 78–83
  • Fichelson S., Freyssinier J. M., Picard F., Fontenay‐Roupie M., Guesnu M., Cherai M., Gisselbrecht S., Porteu F. Megakaryocyte growth and development factor‐induced proliferation and differentiation are regulated by the mitogen‐activated protein kinase pathway in primitive cord blood hematopoietic progenitors. Blood 1999; 94: 1601–1613
  • Racke F. K., Lewandowska K., Goueli S., Goldfarb A. N. Sustained activation of the extracellular signal‐regulated kinase mitogen‐activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. J Biol Chem 1997; 272: 23366–23370
  • Okuma E., Inazawa Y., Saeki K., You A. Potential roles of extracellular signal‐regulated kinase but not p38 during myeloid differentiation of U937 cells stimulated by cytokines: augmentation of differentiation via prolonged activation of extracellular signal‐regulated kinase. Exp Hematol 2002; 30: 571–581
  • Wilkinson B., Kaye. Requirement for sustained MAPK signaling in both CD4 and CD8 lineage commitment: a threshold model. J Cell Immunol 2001; 211: 86–95
  • Yim S. H., Hammer J. A., Quarles R. H. Differences in signal transduction pathways by which platelet‐derived and fibroblast growth factors activate extracellular signal‐regulated kinase in differentiating oligodendrocytes. J Neurochem 2001; 76: 1925–1934
  • Marshall C. J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal‐regulated kinase activation. Cell 1995; 80: 179–185
  • Mendes P. Biochemistry by numbers: simulation of biochemical pathways with GEPASI 3. Trends Biochem Sci 1997; 22: 361–363
  • Brown K. D., Yeh Y.‐C., Holley R. W. Binding, internalization, and degradation of epidermal growth factor by Balb 3T3 and {BP3T3} cells: relationship to cell density and the stimulation of cell proliferation. J Cell Physiol 1979; 100: 227–238
  • Das M., Miyakawa T., Fox C. F., Pruss R. M., Aharonoz A., Herschman H. R. Specific radiolabeling of a cell surface receptor for epidermal growth factor. Proc Natl Acad Sci USA 1977; 74: 2790–2794
  • Gibbs J. B., Ellis R. W., Scolnick E. M. Autophosporylation of V‐Ha‐Ras P21 is modulated by amino acid residue 12. Proc Natl Acad Sci USA 1984; 81: 2674–2678
  • Gullick W. J., Downward D. J.H., Marsden J. J., Waterfield M. D. A radioimmunoassay for human epidermal growth factor receptor. Anal Biochem 1984; 141: 253–261
  • Haigler H., Ash J. F., Singer S. J., Cohen S. Visualization bu fluorescence of the binding and internalization of EGF in human carcinoma A431. Proc Natl Acad Sci USA 1978; 75: 3317–3321
  • Haj F. G., Markova B., Klaman L. D., Bohmer F. D., Neel B. G. Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase‐1B. J Biol Chem 2003; 278: 739–744
  • Haj F. G., Verveer P. J., Squire A., Neel B. G., Basteiens P. I. Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Science 2002; 295: 1708–1711
  • Ji Q. S., Carpenter G. Role of basal calcium in the EGF activation of MAP kinases. Oncogene 2000; 19: 1853–1856
  • Lee R.‐M., Cobb M. H., Blackshear P. J. Evidence that extracellular signal‐regulated kinases are the insulin‐activated Raf‐1 kinase. J Biol Chem 1992; 267: 1088–1092
  • Mendes P., Kell D. B. Non‐linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation. Bioinformatics 1998; 14: 869–883
  • Weber W., Bertics P. J., Gill G. N. Immunoaffinity purification of the epidermal growth factor receptor. J Biol Chem 1984; 259: 14631–14636
  • Schoeberl B., Eichler‐Jonsson C., Gilles E. D., Muller G. Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Nature Biotechnol 2002; 20: 370–375
  • Sorkina T., Huang F., Beguinot L., Sorkin A. Effect of tyrosine kinase inhibitors on clathrin‐coated pit recruitment and internalization of epidermal growth factor receptor. J Biol Chem 2002; 277: 27433–27441
  • Jiang X. J., Sorkin A. Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. Mol Biol Cell 2002; 13: 1522–1535
  • Traverse S., Seedorf K., Paterson H., Marshall C. J., Cohen P., Ullrich A. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr Biol 1994; 4: 694–701
  • Yaka R., Gamliel A., Gurwitz D., Stein R. NGF induces transient but not sustained activation of ERK in PC12 mutant cells incapable of differentiating. J Cell Biochem 1998; 70: 425–432
  • Schlessinger J., Bar‐Sagi D. Activation of Ras and other signaling pathways by receptor tyrosine kinases. Cold Spring Harb Symp Quant Biol 1994; LIX: 173–179
  • Montgomery R. B., Moscatello D. K., Wong A. J., Cooper J. A., Stahl W. L. Differential modulation of mitogen‐activated protein (MAP) kinase extracellular signal‐related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor. J Biol Chem 1995; 270: 30562–30566
  • Yamada M., Ikeuchi T., Aimoto S., Hatanaka H. PC12h‐R cell, a subclone of PC12 cells, shows EGF‐induced neuronal differentiation and sustained signaling. J Neurosci Res 1996b; 43: 355–364
  • Yamada M., Ikeuchi T., Aimoto S., Hatanaka H. EGF‐induced sustained tyrosine phosphorylation and decreased rate of down‐regulation of EGF receptor in PC12h‐R cells which show neuronal differentiation in response to EGF. Neurochem Res 1996a; 21: 815–822
  • Castellino A. M., Chao M. V. Differential association of phosphatidylinositol‐5‐phosphate 4‐kinase with the EGF/ErbB family of receptors. Cell Signal 1999; 11: 171–177
  • Carpenter G. The EGF receptor: a nexus for trafficking and signaling. BioEssays 2000; 22: 697–707
  • Pang L., Sawada T., Decker S. J., Saltiel A. R. Inhibition of MAP kinase kinase blocks the differentiation of PC‐12 cells induced by nerve growth factor. J Biol Chem 1995; 270: 13585–13588
  • Lin S. Y., Makino K., Xia W., Matin A., Wen Y., Kwong K. Y., Bourguignon L., Hung M. C. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol 2001; 3: 802–808
  • Kimmelman A. C., Rodriguez N. N., Chan A. M. R‐Ras3/M‐Ras induces neuronal differentiation of PC12 cells through cell‐type‐specific activation of the mitogen‐activated protein kinase cascade. Mol Cell Biol 2002; 22: 5946–5961
  • Jiang X., Huang F., Marusyk A., Sorkin A. Grb2 regulates internalization of EGF receptors through clathrin‐coated pits. Mol Biol Cell 2003; 14: 858–870

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.