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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 15
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Original Articles

USE OF METHYLLITHIUM IN METAL/HALOGEN EXCHANGE; A MILD AND EFFICIENT METHOD FOR THE SYNTHESIS OF ORTHO SUBSTITUTED TOLUENES

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Pages 2323-2327 | Received 27 Jan 2000, Published online: 09 Nov 2006

REFERENCES

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  • All starting materials were commercially available with the exception of the N,N-dimethyl compound, prepared according to the method of Giumanini et al. from the corresponding dibromoaniline.20
  • Refers to isolated yields in which the balance is made up of starting material, unless otherwise stated
  • A non-pyrophoric solution supplied by Chemetall GMBH, Langelsheim, Germany
  • All compounds were characterised by mass spectrometry,1Hand 13C nmr.
  • Giumanini , A. G. , Chiavari , G. , Musiani , M. M. and Rossi , P. 1980 . Synthesis , : 743

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