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Invited Review

Contact lenses for ophthalmic drug delivery

, OD PhD FAAO
Pages 494-512 | Received 31 Mar 2017, Accepted 03 Jul 2017, Published online: 15 Apr 2021

REFERENCES

  • Wichterle O, Lim D, inventors. Method for producing shaped articles from three‐dimensional hydrophilic polymers. US patent # 2 976 5761961.
  • White CJ, Byrne ME. Molecularly imprinted therapeutic contact lenses. Expert Opin Drug Deliv 2010; 7: 765–780.
  • Stone GW, Ellis SG, Cox DA et al. A polymer‐based, paclitaxel‐eluting stent in patients with coronary artery disease. N Engl J Med 2004; 350: 221–231.
  • Lammer J, Malagari K, Vogl T et al. Prospective randomized study of doxorubicin‐eluting‐bead embolization in the treatment of hepatocellular carcinoma: Results of the PRECISION v study. Cardiovasc Intervent Radiol 2010; 33: 41–52.
  • Masri BA, Duncan CP, Beauchamp CP. Long‐term elution of antibiotics from bone‐cement: An in vivo study using the prosthesis of antibiotic‐loaded acrylic cement (PROSTALAC) system. J Arthroplasty 1998; 13: 331–338.
  • Morgan PB, Woods CA, Tranoudis IG. International contact lens prescribing in 2009. Contact Lens Spectrum 2010; 2: 30–36.
  • Efron N, Morgan PB, Woods CA et al. An international survey of daily disposable contact lens prescribing. Clin Exp Optom 2013; 96: 58–64.
  • Bartlett JD, Jaanus SD. Clinical ocular pharmacology. 5th edn. St. Louis: Butterworth‐Heinemann/Elsevier; 2008. xvi, pp 793.
  • Farkouh A, Frigo P, Czejka M. Systemic side effects of eye drops: A pharmacokinetic perspective. Clin Ophthalmol 2016; 10: 2433–2441.
  • Okeke CO, Quigley HA, Jampel HD et al. Adherence with topical glaucoma medication monitored electronically the Travatan Dosing Aid study. Ophthalmology. 2009; 116: 191–199.
  • Hui A, Willcox M. In vivo studies evaluating the use of contact lenses for drug delivery. Optom Vis Sci 2016; 93: 367–376.
  • Carvalho IM, Marques CS, Oliveira RS, Coelho PB, Costa PC, Ferreira DC. Sustained drug release by contact lenses for glaucoma treatment: A review. J Control Release 2015; 202: 76–82.
  • Boone A, Hui A, Jones L. Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses. Eye Contact Lens 2009; 35: 260–267.
  • Hui A, Boone A, Jones L. Uptake and release of ciprofloxacin‐HCl from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 2008; 34: 266–271.
  • Soluri A, Hui A, Jones L. Delivery of ketotifen fumarate by commercial contact lens materials. Optom Vis Sci 2012; 89: 1140–1149.
  • Karlgard C, Jones L, Moresoli C. Uptake and release of Acular from silicone‐hydrogel and conventional hydrogel contact lens materials. Optom Vis Sci 2000; 77: 179.
  • Karlgard C, Jones L, Moresoli C. Uptake and release of ciloxan from silicone‐hydrogel and conventional hydrogel contact lens materials. Invest Ophthalmol Vis Sci 2001; 42: s592.
  • Karlgard CC, Jones LW, Moresoli C. Ciprofloxacin interaction with silicon‐based and conventional hydrogel contact lenses. Eye Contact Lens 2003; 29: 83–89.
  • Pankey GA, Sabath LD. Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram‐positive bacterial infections. Clin Infect Dis 2004; 38: 864–870.
  • Peng CC, Kim J, Chauhan A. Extended delivery of hydrophilic drugs from silicone‐hydrogel contact lenses containing vitamin E diffusion barriers. Biomaterials 2010; 31: 4032–4047.
  • Kim J, Peng CC, Chauhan A. Extended release of dexamethasone from silicone‐hydrogel contact lenses containing vitamin E. J Control Release 2010; 148: 110–116.
  • Peng CC, Burke MT, Chauhan A. Transport of topical anesthetics in vitamin e loaded silicone hydrogel contact lenses. Langmuir 2012; 28: 1478–1487.
  • Hsu KH, Fentzke RC, Chauhan A. Feasibility of corneal drug delivery of cysteamine using vitamin e modified silicone hydrogel contact lenses. Eur J Pharm Biopharm 2013; 85: 531–540.
  • Hsu KH, De la jara PL, Ariyavidana A et al. Release of betaine and dexpanthenol from vitamin E modified silicone‐hydrogel contact lenses. Curr Eye Res 2015; 40: 267–273.
  • Paradiso P, Serro AP, Saramago B, Colaço R, Chauhan A. Controlled release of antibiotics from Vitamin E‐loaded silicone‐hydrogel contact lenses. J Pharm Sci 2016; 105: 1164–1672.
  • Alexander C, Andersson HS, Andersson LI et al. Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003. J Mol Recognit 2006; 19: 106–180.
  • Byrne ME, Salian V. Molecular imprinting within hydrogels II: Progress and analysis of the field. Int J Pharm 2008; 364: 188–212.
  • Ye L, Mosbach K. Molecular imprinting: Synthetic materials as substitutes for biological antibodies and receptors. Chemistry of Materials 2008; 20: 859–868.
  • Alvarez‐lorenzo C, Concheiro A. Molecularly imprinted polymers for drug delivery. J Chromatography B Analyt Technol Biomed Life Sci 2004; 804: 231–245.
  • Alvarez‐lorenzo C, Yañez F, Barreiro‐iglesias R, Concheiro A. Imprinted soft contact lenses as norfloxacin delivery systems. J Control Release. 2006; 113: 236–244.
  • González‐chomón C, Silva M, Concheiro A, Alvarez‐lorenzo C. Biomimetic contact lenses eluting olopatadine for allergic conjunctivitis. Acta Biomaterialia 2016; 41: 302–311.
  • Green JA, Phillips KS, Hitchins VM et al. Material properties that predict preservative uptake for silicone hydrogel contact lenses. Eye Contact Lens 2012; 38: 350–357.
  • Hutter JC, Green JA, Eydelman MB. Proposed silicone hydrogel contact lens grouping system for lens care product compatibility testing. Eye Contact Lens 2012; 38: 358–362.
  • Hui A, Boone A, Jones L. Uptake and release of ciprofloxacin‐HCl from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 2008; 34: 266–271.
  • Kanemoto M, Sato T, Aoyama A et al. The interaction and compatibility between a soft contact lens and an ophthalmic drug. Eye Contact Lens 2006; 32: 192–196.
  • Sato T, Uchida R, Tanigawa H, Uno K, Murakami A. Application of polymer gels containing side‐chain phosphate groups to drug‐delivery contact lenses. J App Polymer Sci 2005; 98: 731–735.
  • Kakisu K, Matsunaga T, Kobayakawa S, Sato T, Tochikubo T. Development and efficacy of a drug‐releasing soft contact lens. Invest Ophthalmol Vis Sci 2013; 54: 2551–2561.
  • Makadia H, Siegel SJ. Poly lactic‐co‐glycolic acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers 2011; 3: 1377–1397.
  • Ciolino JB, Hoare TR, Iwata NG et al. A drug‐eluting contact lens. Invest Ophthalmol Vis Sci 2009; 50: 3346–3352.
  • Ciolino JB, Hudson SP, Mobbs AN et al. A prototype antifungal contact lens. Invest Ophthalmol Vis Sci 2011; 52: 6286–6291.
  • Ciolino JB, Stefanescu CF, Ross AE et al. In vivo performance of a drug‐eluting contact lens to treat glaucoma for a month. Biomaterials 2014; 35: 432–439.
  • Danion A, Arsenault I, Vermette P. Antibacterial activity of contact lenses bearing surface‐immobilized layers of intact liposomes loaded with levofloxacin. J Pharm Sci 2007; 96: 2350–2363.
  • Phan CM, Subbaraman L, Liu S, Gu F, Jones L. In vitro uptake and release of natamycin Dex‐b‐PLA nanoparticles from model contact lens materials. J Biomater Sci Polym Ed 2014; 25: 18–31.
  • Stapleton F, Carnt N. Contact lens‐related microbial keratitis: how have epidemiology and genetics helped us with pathogenesis and prophylaxis? Eye (Lond) 2012; 26: 185–193.
  • Hui A, Sheardown H, Jones L. Acetic and acrylic acid molecular imprinted model silicone hydrogel materials for ciprofloxacin‐HCL delivery. Materials 2012; 5: 85–107.
  • Hui A, Willcox M, Jones L. In vitro and in vivo evaluation of novel ciprofloxacin‐releasing silicone hydrogel contact lenses. Invest Ophthalmol Vis Sci 2014; 55: 4896–4904.
  • Phan CM, Subbaraman LN, Jones L. In vitro uptake and release of natamycin from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 2013; 39: 162–168.
  • Bajgrowicz M, Phan CM, Subbaraman LN, Jones L. Release of ciprofloxacin and moxifloxacin from daily disposable contact lenses from an in vitro eye model. Invest Ophthalmol Vis Sci 2015; 56: 2234–2242.
  • Phan CM, Bajgrowicz M, Mccanna DJ, Subbaraman LN, Jones L. Effects of antifungal soaked silicone hydrogel contact lenses on Candida albicans in an agar eye model. Eye Contact Lens 2016; 42: 313–317.
  • Alcon Canada Inc. Product monograph: Ciloxan 0.3% ciprofloxacin hydrochloride ophthalmic solution and ointment (0.3% as ciprofloxacin) antibacterial agent. 1992. [Cited 25 Aug 2017.] Available at: http://visioninstitutecanada.com/documents/tpa_resource/CILOXAN%20‐%20ALCON.pdf.
  • Busin M, Spitznas M. Sustained gentamicin release by presoaked medicated bandage contact lenses. Ophthalmology 1988; 95: 796–798.
  • Hehl EM, Beck R, Luthard K, Guthoff R, Drewelow B. Improved penetration of aminoglycosides and fluoroquinolones into the aqueous humour of patients by means of Acuvue contact lenses. Eur J Clin Pharmacol 1999; 55: 317–323.
  • Machetta F, Fea AM, Actis AG, de Sanctis U, Dalmasso P, Grignolo FM. In vivo confocal microscopic evaluation of corneal langerhans cells in dry eye patients. Open Ophthalmol J 2014; 8: 51–59.
  • Malakooti N, Alexander C, Alvarez‐lorenzo C. Imprinted contact lenses for sustained release of polymyxin B and related antimicrobial peptides. J Pharm Sci 2015; 104: 3386–3394.
  • Jaishankar D, Buhrman JS, Valyi‐nagy T, Gemeinhart RA, Shukla D. Extended release of an anti–heparan sulfate peptide from a contact lens suppresses corneal herpes simplex virus‐1 infection. Invest Ophthalmol Vis Sci 2016; 57: 169–180.
  • Behl G, Iqbal J, O’reilly NJ, Mcloughlin P, Fitzhenry L. Synthesis and characterization of poly(2‐hydroxyethylmethacrylate) contact lenses containing chitosan nanoparticles as an ocular delivery system for dexamethasone sodium phosphate. Pharm Res 2016; 33: 1638–1648.
  • Calvo P, Remunan‐lopez C, Vila‐jato JL, Alonso MJ. Chitosan and chitosan/ethylene oxide‐propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharm Res 1997; 14: 1431–1436.
  • Malaekeh‐nikouei B, Ghaeni FA, Motamedshariaty VS, Mohajeri SA. Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses. J App Polymer Sci 2012; 126: 387–394.
  • Karlgard CC, Wong NS, Jones LW, Moresoli C. In vitro uptake and release studies of ocular pharmaceutical agents by silicon‐containing and p‐HEMA hydrogel contact lens materials. Int J Pharm 2003; 257: 141–151.
  • Tieppo A, Pate KM, Byrne ME. In vitro controlled release of an anti‐inflammatory from daily disposable therapeutic contact lenses under physiological ocular tear flow. Eur J Pharm Biopharm 2012; 81: 170–177.
  • Solomon R, Perry HD, Donnenfeld ED, Greenman HE. Slitlamp biomicroscopy of the tear film of patients using topical Restasis and Refresh Endura. J Cataract Refract Surg 2005; 31: 661–663.
  • Kapoor Y, Chauhan A. Ophthalmic delivery of Cyclosporine A from Brij‐97 microemulsion and surfactant‐laden p‐HEMA hydrogels. Int J Pharm 2008; 361: 222–229.
  • Kapoor Y, Thomas JC, Tan G, John VT, Chauhan A. Surfactant‐laden soft contact lenses for extended delivery of ophthalmic drugs. Biomaterials 2009; 30: 867–878.
  • Peng CC, Chauhan A. Extended cyclosporine delivery by silicone‐hydrogel contact lenses. J Control Release 2011; 154: 267–274.
  • Jain MR, Batra V. Steroid penetration in human aqueous with 'Sauflon 70' lenses. Indian J Ophthalmol 1979; 27: 26–31.
  • Xu J, Li X, Sun F. In vitro and in vivo evaluation of ketotifen fumarate‐loaded silicone hydrogel contact lenses for ocular drug delivery. Drug Delivery 2011; 18: 150–158.
  • Venkatesh S, Sizemore SP, Byrne ME. Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics. Biomaterials 2007; 28: 717–724.
  • Venkatesh S, Saha J, Pass S, Byrne ME. Transport and structural analysis of molecular imprinted hydrogels for controlled drug delivery. Eur J Pharm Biopharm 2008; 69: 852–860.
  • Ali M, Horikawa S, Venkatesh S, Saha J, Hong JW, Byrne ME. Zero‐order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow. J Control Release. 2007; 124: 154–162.
  • Tieppo A, White CJ, Paine AC, Voyles ML, Mcbride MK, Byrne ME. Sustained in vivo release from imprinted therapeutic contact lenses. J Control Release 2012; 157: 391–397.
  • Schultz CL, Poling TR, Mint JO. A medical device/drug delivery system for treatment of glaucoma. Clin Exp Optom 2009; 92: 343–348.
  • Hillman JS. Management of acute glaucoma with Pilocarpine soaked hydrophilic lens. Br J Ophthalmol 1974; 58: 674–679.
  • Peng CC, Ben‐shlomo A, Mackay EO, Plummer CE, Chauhan A. Drug delivery by contact lens in spontaneously glaucomatous dogs. Curr Eye Res 2012; 37: 204–211.
  • Villani E, Garoli E, Termine V, Pichi F, Ratiglia R, Nucci P. Corneal confocal microscopy in dry eye treated with corticosteroids. Optom Vis Sci 2015; 92: e290–e295.
  • Hsu KH, Carbia BE, Plummer C, Chauhan A. Dual drug delivery from vitamin e loaded contact lenses for glaucoma therapy. Eur J Pharm Biopharm 2015; 94: 312–321.
  • Alvarez‐lorenzo C, Hiratani H, Gómez‐amoza JL, Martínez‐pacheco R, Souto C, Concheiro A. Soft contact lenses capable of sustained delivery of timolol. J Pharm Sci 2002; 91: 2182–2192.
  • Hiratani H, Alvarez‐lorenzo C. Timolol uptake and release by imprinted soft contact lenses made of N,N‐diethylacrylamide and methacrylic acid. J Control Release 2002; 83: 223–230.
  • Hiratani H, Fujiwara A, Tamiya Y, Mizutani Y, Alvarez‐lorenzo C. Ocular release of timolol from molecularly imprinted soft contact lenses. Biomaterials 2005; 26: 1293–1298.

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