Efficacy of azithromycin 1% ophthalmic solution for treatment of ocular surface disease from posterior blepharitis

REFERENCES

• Henriquez A, Korb DR. Meibomian glands and contact lens wear. Br J Ophthalmol 1981; 65: 108–111.
   PubMed Web of Science ®Google Scholar
• Mcculley JP, Dougherty JM, Deneau DG. Chronic Blepharitis: Classification and mechanisms. Immunol Abstsr 1981; 55–72.
   Google Scholar
• Mcculley JP, Dougherty JM, Deneau DG. Classification of chronic blepharitis. Ophthalmology 1982; 89: 1173–1180.
   PubMed Web of Science ®Google Scholar
• Dougherty JM, Mcculley JP. Tear lysozyme measurements in chronic blepharitis. Ann Ophthalmol 1985; 17: 53–57.
   Google Scholar
• Dougherty JM, Mcculley JP, Meyer DR. Keratoconjunctivitis sicca and tear lysozyme in chronic blepharitis. In: Holley FJ, ed.The Preocular Tear Film. Lubbock, Texas: Dry Eye Institute, 1984. pp.176–181.
   Google Scholar
• Bowman RW, Dougherty JM, and Mcculley JP. Chronic blepharitis and dry eyes. Int Ophthalmol Clin 1987; 27: 27–35.
   PubMedGoogle Scholar
• Jester JV, Nicolaides N, Smith RE. Meibomian gland dysfunction. I. Keratin protein expression in normal human and rabbit meibomian glands. Invest Ophthalmol Vis Sci 1989; 30: 927–935.
   PubMed Web of Science ®Google Scholar
• Jester JV, Nicolaides N, Kiss‐palvolgy I, Smith RE. Meibomian gland dysfunction. II. The role of keratinization in a rabbit model of MGD. Invest Ophthalmol Vis Sci 1989; 30: 936–945.
   PubMed Web of Science ®Google Scholar
• Nicolaides N, Santos EC, Smith RE, Jester JV. Meibomian gland dysfunction. III. Meibomian gland lipids. Invest Ophthalmol Vis Sci 1989; 30: 946–951.
   PubMed Web of Science ®Google Scholar
• Bron AJ, Tiffany JM. The contribution of meibomian disease to dry eye. Ocul Surf 2004; 2: 149–165.
   PubMedGoogle Scholar
• Foulks GN, Bron AJ. Meibomian gland dysfunction: a clinical scheme for description, diagnosis, classification, and grading. Ocul Surf 2003; 1: 107–126.
   PubMedGoogle Scholar
• Driver PJ, Lemp MA. Meibomian gland dysfunction. Surv Ophthalmol 1996; 40: 343–367.
   PubMed Web of Science ®Google Scholar
• Dougherty JM, Mcculley JP. Comparative bacteriology of chronic blepharitis. Br J Ophthalmol 1984; 68: 524–528.
   PubMed Web of Science ®Google Scholar
• Mcculley JP, Dougherty JM. Bacterial aspects of chronic blepharitis. Trans Ophthalmol Soc UK 1986; 105: 314–318.
   PubMedGoogle Scholar
• Kellum RE. Acne vulgarus: Studies in pathogenesis: Relative irritancy of free fatty acids from C2 to CM. Arch Dermatol 1968; 97: 722–726.
   PubMedGoogle Scholar
• Shine WE, Mcculley JP. Role of wax ester fatty alcohols in chronic blepharitis. Invest Ophthalmol Vis Sci 1993; 34: 3515–3521.
   PubMed Web of Science ®Google Scholar
• Mcculley JP, Shine WE. Meibomian gland function and the tear lipid layer. Ocul Surf 2003; 1: 97–106.
   PubMedGoogle Scholar
• Jackson WB. Blepharitis: current strategies for diagnosis and management. Can J Ophthalmol 2008; 43: 170–179.
   PubMed Web of Science ®Google Scholar
• Shine WE, Mcculley JP. Polar lipids in human meibomian gland secretions. Curr Eye Res 2003; 26: 89–94.
   PubMed Web of Science ®Google Scholar
• Shine WE, Mcculley JP. Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality. Arch Ophthalmol 1998; 116: 849–852.
   PubMedGoogle Scholar
• Hom MM, Martinson JR, Knapp LL, Paugh JR. Prevalence of meibomian gland dysfunction. Optom Vis Sci 1990; 67: 710–712.
   PubMed Web of Science ®Google Scholar
• Ong BL, Larake JR. Meibomian gland dysfunction: some clinical, biochemical and physical observations. Ophthalmic Physiol Opt 1990; 10: 144–148.
   PubMed Web of Science ®Google Scholar
• Ong BL. Relationship between contact lens wear and meibomian gland dysfunction. Optom Vis Sci 1996; 73: 208–210.
   Web of Science ®Google Scholar
• Romero JM, Biser SA, Perry HD, Levinson DH, Doshi SJ, Terraciano A, Donnenfeld ED. Conservative treatment of meibomian gland dysfunction. Eye Contact Lens 2004; 30: 14–19.
   PubMedGoogle Scholar
• Olson MC, Korb DR, Greiner JV. Increase in tear film lipid layer thickness following treatment with warm compresses in patients with meibomian gland dysfunction. Eye Contact Lens 2003; 29: 96–99.
   PubMedGoogle Scholar
• Frucht‐pery J, Sagi E, Hemo I, Ever‐hadani P. Efficacy of doxycycline and tetracyclines in ocular rosacea. Am J Ophthalmol 1993; 116: 88–92.
   PubMed Web of Science ®Google Scholar
• Dougherty JM, Mcculley JP, Silvany RE, Meyer DR. The role of tetracycline in chronic blepharitis. Inhibition of lipase production in staphylococci. Invest Ophthalmol Vis Sci 1991; 32: 2970–2975.
   PubMed Web of Science ®Google Scholar
• Pinna A, Piccinini P, Carta F. Effect of oral linoleic and γ‐linolenic acid on meibomian gland dysfunction. Cornea 2007; 26: 260–264.
   PubMed Web of Science ®Google Scholar
• Mascai MS. The role of omega‐3 dietary supplementation in blepharitis and meibomian gland dysfunction. Trans Am Ophthalmol Soc 2008; 106: 336–356.
   Google Scholar
• Perry HD, Doshi‐carnevale S, Donnenfeld ED, Solomon R, Biser SA, Bloom AH. Efficacy of commercially available topical cyclosporine A 0.05% in the treatment of meibomian gland dysfunction. Cornea 2006; 25: 71–175.
   Web of Science ®Google Scholar
• Rubin M, Rao SN. Efficacy of topical Cyclosporin 0.05% in the treatment of posterior blepharitis. J Ocul Pharmacol Ther 2006: 22: 47–53.
   PubMed Web of Science ®Google Scholar
• Fiedlaender MH, Protzko E. Clinical development of 1% azithromycin in durasite, a topical azalide anti‐infective for ocular surface therapy. Clin Ophthalmol 2007; 1: 3–10.
   Google Scholar
• Amar T, Caillaud T, Elena PP. Ocular pharmacokinetic study following single and multiple azithromycin administrations in pigmented rabbits. Curr Eye Res 2008; 33: 149–158.
   PubMed Web of Science ®Google Scholar
• Ianaro A, Ialenti A, Maffia P, Sautebin L, Rombolà L, Carnuccio R, Iuvone T et al. Anti‐inflammatory activity of macrolide antibiotics. J Pharmacol Exp Ther 2000; 292: 156–163.
   PubMed Web of Science ®Google Scholar
• Scaglione F, Rossoni G. Comparative anti‐inflammatory effects of roxithromycin, azithromycin and clarithromycin. J Antimicrob Chemother 1998; 41: 47–50.
   PubMedGoogle Scholar
• Aghai ZH, Kode A, Saslow JG, Nakhla T, Farhath S, Stahl GE, Eydelman R et al. Azithromycin suppresses activation of nuclear factor‐kappa B and synthesis of pro‐inflammatory cytokines in tracheal aspirate cells from premature infants. Pediatr Res 2007; 62: 483–488.
   PubMed Web of Science ®Google Scholar
• Li DQ, Zhou N, Zhang L, Ma P, Pflugfelder SC. Azithromycin suppresses Zymosan‐induced production of pro‐inflammatory mediators by human corneal epithelial cells. Invest Ophthalmol Vis Sci 2010Jun 10. [Epub ahead of print]
   Google Scholar
• Luchs J. Efficacy of topical azithromycin ophthalmic solution 1% in the treatment of posterior blepharitis. Adv Ther 2008; 25: 858–870.
   PubMed Web of Science ®Google Scholar
• John T, Shah AA. Use of azithromycin ophthalmic solution in the treatment of chronic mixed anterior blepharitis. Ann Ophthalmol (Skokie) 2008; 40: 68–74.
   PubMed Web of Science ®Google Scholar
• Perry HD, Solomon R, Donnenfeld ED, Perry AR, Wottpenn JR, Greenman HE, Savage HE. Evaluation of topical cyclosporine for the treatment of dry eye disease. Arch Ophthalmol 2008; 126: 1046–1050.
   PubMedGoogle Scholar
• Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol 2000; 118: 615–621.
   PubMed Web of Science ®Google Scholar
• Nicolaides N, Kaitaranta JK, Rowdah TN, Macy JI, Boswell FM, Smith RE. Meibomian gland studies: Comparison of steer and human lipids. Invest Ophthalmol Vis Sci 1981; 20: 522–536.
   PubMed Web of Science ®Google Scholar
• Shine WE, Mcculley JP. Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality. Arch Ophthalmol 1998; 116: 849–852.
   PubMedGoogle Scholar
• Mcculley JP, Shine WE. Changing concepts in the diagnosis and management of blepharitis. Cornea 2000; 19: 650–658.
   PubMed Web of Science ®Google Scholar
• Zengin N, Tol H, Gunduz K, Okudan S, Balevi S, Endogru H. Meibomian gland dysfunction and tear film abnormalities in rosacea. Cornea 1995; 14: 144–146.
   PubMed Web of Science ®Google Scholar
• Protzko E, Bowman L, Abelson M, Shapiro A, AzaSite Clinical Study Group. Phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops versus 0.3% tobramycin eye drops for bacterial conjunctivitis. Invest Ophthalmol Vis Sci 2007; 48: 3425–3429.
   PubMed Web of Science ®Google Scholar
• Lemp MA, Nichols KK. Blepharitis in the United States 2009: a survey‐based perspective on prevalence and treatment. Ocul Surf 2009April 7; (2Suppl): S1–S14.
   Web of Science ®Google Scholar