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Article

MAVS Regulates Apoptotic Cell Death by Decreasing K48-Linked Ubiquitination of Voltage-Dependent Anion Channel 1

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Pages 3137-3149 | Received 13 Jan 2013, Accepted 30 May 2013, Published online: 20 Mar 2023

REFERENCES

  • Goldenthal MJ, Marin-Garcia J. 2004. Mitochondrial signaling pathways: a receiver/integrator organelle. Mol. Cell. Biochem. 262:1–16.
  • Green DR, Reed JC. 1998. Mitochondria and apoptosis. Science 281:1309–1312.
  • Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167–1172.
  • Ow YP, Green DR, Hao Z, Mak TW. 2008. Cytochrome c: functions beyond respiration. Nat. Rev. Mol. Cell Biol. 9:532–542.
  • Crompton M. 1999. The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 341(Pt 2):233–249.
  • Granville DJ, Gottlieb RA. 2003. The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death. Curr. Med. Chem. 10:1527–1533.
  • Le Bras M, Clement MV, Pervaiz S, Brenner C. 2005. Reactive oxygen species and the mitochondrial signaling pathway of cell death. Histol. Histopathol. 20:205–219.
  • Lemasters JJ, Holmuhamedov E. 2006. Voltage-dependent anion channel (VDAC) as mitochondrial governator—thinking outside the box. Biochim. Biophys. Acta 1762:181–190.
  • Colombini M. 2004. VDAC: the channel at the interface between mitochondria and the cytosol. Mol. Cell. Biochem. 256–257:107–115.
  • Shoshan-Barmatz V, Gincel D. 2003. The voltage-dependent anion channel: characterization, modulation, and role in mitochondrial function in cell life and death. Cell Biochem. Biophys. 39:279–292.
  • Shoshan-Barmatz V, Israelson A, Brdiczka D, Sheu SS. 2006. The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death. Curr. Pharm. Des. 12:2249–2270.
  • Vyssokikh M, Brdiczka D. 2004. VDAC and peripheral channelling complexes in health and disease. Mol. Cell. Biochem. 256–257:117–126.
  • Walsh D, McCarthy J, O'Driscoll C, Melgar S. 2013. Pattern recognition receptors—molecular orchestrators of inflammation in inflammatory bowel disease. Cytokine Growth Factor Rev. 24:91–104.
  • Lavelle EC, Murphy C, O'Neill LA, Creagh EM. 2010. The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis. Mucosal Immunol. 3:17–28.
  • Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730–737.
  • Kawai T, Akira S. 2006. Innate immune recognition of viral infection. Nat. Immunol. 7:131–137.
  • Meylan E, Tschopp J. 2006. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol. Cell 22:561–569.
  • Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122:669–682.
  • Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S. 2005. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6:981–988.
  • Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. 2005. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19:727–740.
  • Scott I, Norris KL. 2008. The mitochondrial antiviral signaling protein, MAVS, is cleaved during apoptosis. Biochem. Biophys. Res. Commun. 375:101–106.
  • Besch R, Poeck H, Hohenauer T, Senft D, Hacker G, Berking C, Hornung V, Endres S, Ruzicka T, Rothenfusser S, Hartmann G. 2009. Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J. Clin. Invest. 119:2399–2411.
  • Rintahaka J, Wiik D, Kovanen PE, Alenius H, Matikainen S. 2008. Cytosolic antiviral RNA recognition pathway activates caspases 1 and 3. J. Immunol. 180:1749–1757.
  • Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. 2009. MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS One 4:e5466. doi:10.1371/journal.pone.0005466.
  • Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, Wang T, Coyne CB. 2011. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog. 7:e1001311. doi:10.1371/journal.ppat.1001311.
  • Scott I. 2009. Degradation of RIG-I following cytomegalovirus infection is independent of apoptosis. Microbes Infect. 11:973–979.
  • Yu CY, Chiang RL, Chang TH, Liao CL, Lin YL. 2010. The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases. J. Virol. 84:2421–2431.
  • Li HM, Fujikura D, Harada T, Uehara J, Kawai T, Akira S, Reed JC, Iwai A, Miyazaki T. 2009. IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation. Cell Death Differ. 16:1615–1621.
  • Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC. 2010. Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141:668–681.
  • Scott I. 2010. The role of mitochondria in the mammalian antiviral defense system. Mitochondrion 10:316–320.
  • Baril M, Racine ME, Penin F, Lamarre D. 2009. MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease. J. Virol. 83:1299–1311.
  • Tang ED, Wang CY. 2009. MAVS self-association mediates antiviral innate immune signaling. J. Virol. 83:3420–3428.
  • Wen C, Yan Z, Yang X, Guan K, Xu C, Song T, Zheng Z, Wang W, Wang Y, Zhao M, Zhang Y, Xu T, Dou J, Liu J, Xu Q, He X, Wei C, Zhong H. 2012. Identification of tyrosine-9 of MAVS as critical target for inducible phosphorylation that determines activation. PLoS One 7:e41687. doi:10.1371/journal.pone.0041687.
  • Abu-Hamad S, Arbel N, Calo D, Arzoine L, Israelson A, Keinan N, Ben-Romano R, Friedman O, Shoshan-Barmatz V. 2009. The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins. J. Cell Sci. 122:1906–1916.
  • Keinan N, Tyomkin D, Shoshan-Barmatz V. 2010. Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. Mol. Cell. Biol. 30:5698–5709.
  • Shi Y, Chen J, Weng C, Chen R, Zheng Y, Chen Q, Tang H. 2003. Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins. Biochem. Biophys. Res. Commun. 305:989–996.

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