Coa2 Is an Assembly Factor for Yeast Cytochrome c Oxidase Biogenesis That Facilitates the Maturation of Cox1

REFERENCES

• Antonicka, H., S. C. Leary, G. H. Guercin, J. N. Agar, R. Horvath, N. G. Kennaway, C. O. Harding, M. Jaksch, and E. A. Shoubridge. 2003. Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency. Hum. Mol. Genet. 12:2693–2702.
   PubMed Web of Science ®Google Scholar
• Antonicka, H., A. Mattman, C. G. Carlson, D. M. Glerum, K. C. Hoffbuhr, S. C. Leary, N. G. Kennaway, and E. A. Shoubridge. 2003. Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway causing early-onset fatal hypertrophic cardiomyopathy. Am. J. Hum. Genet. 72:101–114.
   PubMed Web of Science ®Google Scholar
• Arlt, H., G. Steglich, R. Perryman, B. Guiard, W. Neupert, and T. Langer. 1998. The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease. EMBO J. 17:4837–4847.
   PubMedGoogle Scholar
• Arlt, H., R. Tauer, H. Feldmann, W. Neupert, and T. Langer. 1996. The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 85:875–885.
   PubMedGoogle Scholar
• Arnold, I., and T. Langer. 2002. Membrane protein degradation by AAA proteases in mitochondria. Biochim. Biophys. Acta 1592:89–96.
   PubMed Web of Science ®Google Scholar
• Banting, G. S., and D. M. Glerum. 2006. Mutational analysis of the Saccharomyces cerevisiae cytochrome c oxidase assembly protein Cox11p. Eukaryot. Cell 5:568–578.
   PubMedGoogle Scholar
• Barrientos, A., D. Korr, and A. Tzagoloff. 2002. Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh's syndrome. EMBO J. 21:43–52.
   PubMed Web of Science ®Google Scholar
• Barrientos, A., A. Zambrano, and A. Tzagoloff. 2004. Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae. EMBO J. 23:3472–3482.
   PubMed Web of Science ®Google Scholar
• Bonnefoy, N., F. Chalvet, P. Hamel, P. P. Slonimski, and G. Dujardin. 1994. OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis. J. Mol. Biol. 239:201–212.
   PubMed Web of Science ®Google Scholar
• Brachat, S., F. S. Dietrich, S. Voegeli, Z. Zhang, L. Stuart, A. Lerch, K. Gates, T. Gaffney, and P. Philippsen. 2003. Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol. 4:R45.
   PubMedGoogle Scholar
• Bradford, N. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248–254.
   PubMed Web of Science ®Google Scholar
• Capaldi, R. A., M. F. Marusich, and J. W. Taanman. 1995. Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells. Methods Enzymol. 260:117–132.
   PubMed Web of Science ®Google Scholar
• Daum, G., P. C. Bohni, and G. Schatz. 1982. Import of proteins into mitochondria. Cytochromeb2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J. Biol. Chem. 257:13028–13033.
   Google Scholar
• Diekert, K., A. I. De Kroon, G. Kispal, and R. Lill. 2001. Isolation and subfractionation of mitochondria from the yeast Saccharomyces cerevisiae. Methods Cell Biol. 65:37–51.
   PubMedGoogle Scholar
• Fontanesi, F., C. Jin, A. Tzagoloff, and A. Barrientos. 2007. Transcriptional activators HAP/NF-Y rescue a cytochrome c oxidase defect in yeast and human cells. Hum. Mol. Genet. 17:775–788.
   PubMedGoogle Scholar
• Glerum, D. M., and A. Tzagoloff. 1997. Submitochondrial distributions and stabilities of subunits 4, 5, and 6 of yeast cytochrome oxidase in assembly defective mutants. FEBS Lett. 412:410–414.
   PubMedGoogle Scholar
• Hell, K., W. Neupert, and R. A. Stuart. 2001. Oxa1p acts as a general membrane insertion machinery for proteins encoded by mitochondrial DNA. EMBO J. 20:1281–1288.
   PubMedGoogle Scholar
• Horan, S., I. Bourges, J.-W. Taanman, and B. Meunier. 2005. Analysis of COX2 mutants reveals cytochrome oxidase subassemblies in yeast. Biochem. J. 390:703–708.
   PubMedGoogle Scholar
• Kastenmayer, J. P., L. Ni, A. Chu, L. E. Kitchen, W. C. Au, H. Yang, C. D. Carter, D. Wheeler, R. W. Davis, J. D. Boeke, M. A. Snyder, and M. A. Basrai. 2006. Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res. 16:365–373.
   PubMed Web of Science ®Google Scholar
• Keller, G., A. Bird, and D. R. Winge. 2005. Independent metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae. Eukaryot. Cell 4:1863–1871.
   PubMedGoogle Scholar
• Khalimonchuk, O., A. Bird, and D. R. Winge. 2007. Evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase. J. Biol. Chem. 282:17442–17449.
   PubMed Web of Science ®Google Scholar
• Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953–961.
   PubMed Web of Science ®Google Scholar
• Manthey, G. M., and J. E. McEwen. 1995. The product of the nuclear gene PET309 is required for translation of mature mRNA and stability or production of intron-containing RNAs derived from the mitochondrial COX1 locus of Saccharomyces cerevisiae. EMBO J. 14:4031–4043.
   PubMed Web of Science ®Google Scholar
• Manthey, G. M., B. D. Przybyla-Zawislak, and J. E. McEwen. 1998. The Saccharomyces cerevisiae Pet309 protein is embedded in the mitochondrial inner membrane. Eur. J. Biochem. 255:156–161.
   PubMedGoogle Scholar
• Mick, D. U., K. Wagner, M. van der Laan, A. E. Frazier, I. Perschil, M. Pawlas, H. E. Meyer, B. Warscheid, and P. Rehling. 2007. Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly. EMBO J. 26:4347–4358.
   PubMed Web of Science ®Google Scholar
• Mumberg, D., R. Muller, and M. Funk. 1994. Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use of heterologous expression. Nucleic Acids Res. 22:5767–5768.
   PubMed Web of Science ®Google Scholar
• Nijtmans, L. G., J. W. Taanman, A. O. Muijsers, D. Speijer, and C. Van den Bogert. 1998. Assembly of cytochrome-c oxidase in cultured human cells. Eur. J. Biochem. 254:389–394.
   PubMedGoogle Scholar
• Perez-Martinez, X., S. A. Broadley, and T. D. Fox. 2003. Mss51p promotes mitochondrial Cox1p synthesis and interacts with newly synthesized Cox1p. EMBO J. 22:5951–5961.
   PubMed Web of Science ®Google Scholar
• Pierrel, F., M. L. Bestwick, P. A. Cobine, O. Khalimonchuk, J. A. Cricco, and D. R. Winge. 2007. Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly. EMBO J. 26:4335–4346.
   PubMed Web of Science ®Google Scholar
• Siep, M., K. van Oosterum, H. Neufeglise, H. van der Spek, and L. A. Grivell. 2000. Mss51p, a putative translational activator of cytochrome c oxidase subunit-1 (COX1) mRNA, is required for synthesis of Cox1p in Saccharomyces cerevisiae. Curr. Genet. 37:213–220.
   PubMedGoogle Scholar
• Smith, D., J. Gray, L. Mitchell, W. E. Antholine, and J. P. Hosler. 2005. Assembly of cytochrome c oxidase in the absence of the assembly protein Surf1p leads to loss of the active site heme. J. Biol. Chem. 280:17652–17656.
   PubMed Web of Science ®Google Scholar
• Stiburek, L., K. Vesela, H. Hansikova, P. Pecina, M. Tesarova, L. Cerna, J. Houstek, and J. Zeman. 2005. Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1. Biochem. J. 392:625–632.
   PubMedGoogle Scholar
• Tatsuta, T., S. Augustin, M. Nolden, B. Friedrichs, and T. Langer. 2007. m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria. EMBO J. 26:325–335.
   PubMed Web of Science ®Google Scholar
• Tsukihara, T., H. Aoyama, E. Yamashita, T. Tomizaki, H. Yamaguchi, K. Shinzawa-Itoh, R. Hakashima, R. Yaono, and S. Yoshikawa. 1995. Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8A. Science 269:1069–1074.
   PubMed Web of Science ®Google Scholar
• Tsukihara, T., H. Aoyama, E. Yamashita, T. Tomizaki, H. Yamaguichi, K. Shinzawa-Itoh, R. Nakashima, R. Yaono, and S. Yoshikawa. 1996. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Science 272:1136–1144.
   PubMed Web of Science ®Google Scholar
• Tzagoloff, A., A. Akai, and R. B. Needleman. 1975. Assembly of the mitochondrial membrane system. Characterization of nuclear mutants of Saccharomyces cerevisiae with defects in mitochondrial ATPase and respiratory enzymes. J. Biol. Chem. 250:8228–8235.
   PubMedGoogle Scholar
• Williams, S. L., I. Valnot, P. Rustin, and J.-W. Taanman. 2004. Cytochrome c oxidase subassemblies in fibroblast cultures from patients carrying mutations in COX10, SCO1 or SURF1. J. Biol. Chem. 279:7462–7469.
   PubMedGoogle Scholar
• Wittig, I., H. P. Braun, and H. Schagger. 2006. Blue native PAGE. Nat. Protoc. 1:418–428.
   PubMed Web of Science ®Google Scholar
• Zambrano, A., F. Fontanesi, A. Solans, R. Leite de Oliveira, T. D. Fox, A. Tzagoloff, and A. Barrientos. 2007. Aberrant translation of cytochrome c oxidase subunit 1 mRNA species in the absence of Mss51p in the yeast Saccharomyces cerevisiae. Mol. Biol. Cell 18:523–535.
   PubMedGoogle Scholar
• Zhu, Z., J. Yao, T. Johns, K. Fu, I. De Bie, C. Macmillan, A. P. Cuthbert, R. F. Newbold, J. Wang, M. Chevrette, G. K. Brown, R. M. Brown, and E. A. Shoubridge. 1998. SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome. Nat. Genet. 20:337–343.
   PubMedGoogle Scholar