Thioredoxin and TRAF Family Proteins Regulate Reactive Oxygen Species-Dependent Activation of ASK1 through Reciprocal Modulation of the N-Terminal Homophilic Interaction of ASK1

REFERENCES

• Chen, J., K. Fujii, L. Zhang, T. Roberts, and H. Fu. 2001. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc. Natl. Acad. Sci. USA 98:7783–7788.
   PubMed Web of Science ®Google Scholar
• Fujino, G., T. Noguchi, K. Takeda, and H. Ichijo. 2006. Thioredoxin and protein kinases in redox signaling. Semin. Cancer Biol. 16:427–435.
   PubMed Web of Science ®Google Scholar
• Galvan, V., A. Logvinova, S. Sperandio, H. Ichijo, and D. E. Bredesen. 2003. Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1). J. Biol. Chem. 278:13325–13332.
   PubMedGoogle Scholar
• Hashimoto, Y., T. Niikura, T. Chiba, E. Tsukamoto, H. Kadowaki, H. Nishitoh, Y. Yamagishi, M. Ishizaka, M. Yamada, M. Nawa, K. Terashita, S. Aiso, H. Ichijo, and I. Nishimoto. 2003. The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization. J. Pharmacol. Exp. Ther. 306:889–902.
   PubMed Web of Science ®Google Scholar
• Hatai, T., A. Matsuzawa, S. Inoshita, Y. Mochida, T. Kuroda, K. Sakamaki, K. Kuida, S. Yonehara, H. Ichijo, and K. Takeda. 2000. Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. J. Biol. Chem. 275:26576–26581.
   PubMed Web of Science ®Google Scholar
• Ichijo, H., E. Nishida, K. Irie, P. ten Dijke, M. Saitoh, T. Moriguchi, M. Takagi, K. Matsumoto, K. Miyazono, and Y. Gotoh. 1997. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275:90–94.
   PubMed Web of Science ®Google Scholar
• Kadowaki, H., H. Nishitoh, F. Urano, C. Sadamitsu, A. Matsuzawa, K. Takeda, H. Masutani, J. Yodoi, Y. Urano, T. Nagano, and H. Ichijo. 2005. Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation. Cell Death Differ. 12:19–24.
   PubMed Web of Science ®Google Scholar
• Kim, A. H., G. Khursigara, X. Sun, T. F. Franke, and M. V. Chao. 2001. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol. Cell. Biol. 21:893–901.
   PubMed Web of Science ®Google Scholar
• Liu, H., H. Nishitoh, H. Ichijo, and J. M. Kyriakis. 2000. Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. Mol. Cell. Biol. 20:2198–2208.
   PubMed Web of Science ®Google Scholar
• Liu, Y., and W. Min. 2002. Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ. Res. 90:1259–1266.
   PubMed Web of Science ®Google Scholar
• Matsuzawa, A., K. Saegusa, T. Noguchi, C. Sadamitsu, H. Nishitoh, S. Nagai, S. Koyasu, K. Matsumoto, K. Takeda, and H. Ichijo. 2005. ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat. Immunol. 6:587–592.
   PubMed Web of Science ®Google Scholar
• Morita, K., M. Saitoh, K. Tobiume, H. Matsuura, S. Enomoto, H. Nishitoh, and H. Ichijo. 2001. Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. EMBO J. 20:6028–6036.
   PubMed Web of Science ®Google Scholar
• Nagai, H., T. Noguchi, K. Takeda, and H. Ichijo. 2007. Pathophysiological roles of ASK1-MAP kinase signaling pathways. J. Biochem. Mol. Biol. 40:1–6.
   PubMedGoogle Scholar
• Nishitoh, H., A. Matsuzawa, K. Tobiume, K. Saegusa, K. Takeda, K. Inoue, S. Hori, A. Kakizuka, and H. Ichijo. 2002. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 16:1345–1355.
   PubMed Web of Science ®Google Scholar
• Nishitoh, H., M. Saitoh, Y. Mochida, K. Takeda, H. Nakano, M. Rothe, K. Miyazono, and H. Ichijo. 1998. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 2:389–395.
   PubMed Web of Science ®Google Scholar
• Noguchi, T., K. Takeda, A. Matsuzawa, K. Saegusa, H. Nakano, J. Gohda, J. Inoue, and H. Ichijo. 2005. Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death. J. Biol. Chem. 280:37033–37040.
   PubMed Web of Science ®Google Scholar
• Saitoh, M., H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, and H. Ichijo. 1998. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17:2596–2606.
   PubMed Web of Science ®Google Scholar
• Takeda, K., T. Hatai, T. S. Hamazaki, H. Nishitoh, M. Saitoh, and H. Ichijo. 2000. Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells. J. Biol. Chem. 275:9805–9813.
   PubMed Web of Science ®Google Scholar
• Takeda, K., A. Matsuzawa, H. Nishitoh, K. Tobiume, S. Kishida, J. Ninomiya-Tsuji, K. Matsumoto, and H. Ichijo. 2004. Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation. EMBO Rep. 5:161–166.
   PubMed Web of Science ®Google Scholar
• Tobiume, K., A. Matsuzawa, T. Takahashi, H. Nishitoh, K. Morita, K. Takeda, O. Minowa, K. Miyazono, T. Noda, and H. Ichijo. 2001. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2:222–228.
   PubMed Web of Science ®Google Scholar
• Tobiume, K., M. Saitoh, and H. Ichijo. 2002. Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of preformed oligomer. J. Cell Physiol. 191:95–104.
   PubMed Web of Science ®Google Scholar
• Zhang, R., R. Al-Lamki, L. Bai, J. W. Streb, J. M. Miano, J. Bradley, and W. Min. 2004. Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner. Circ. Res. 94:1483–1491.
   PubMed Web of Science ®Google Scholar