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Article

Retinoic Acid Utilizes CREB and USF1 in a Transcriptional Feed-Forward Loop in Order To Stimulate MKP1 Expression in Human Immunodeficiency Virus-Infected Podocytes

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Pages 5785-5794 | Received 13 Feb 2008, Accepted 16 Jun 2008, Published online: 27 Mar 2023

REFERENCES

  • Abraham, S. M., T. Lawrence, A. Kleiman, P. Warden, M. Medghalchi, J. Tuckermann, J. Saklatvala, and A. R. Clark. 2006. Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. J. Exp. Med. 203:1883–1889.
  • Allenby, G., M. T. Bocquel, M. Saunders, S. Kazmer, J. Speck, M. Rosenberger, A. Lovey, P. Kastner, J. F. Grippo, P. Chambon, et al. 1993. Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc. Natl. Acad. Sci. USA 90:30–34.
  • Awazu, M., K. Ishikura, et al. 1999. Mechanisms of mitogen-activated protein kinase activation in experimental diabetes. J. Am. Soc. Nephrol. 10:738–745.
  • Awazu, M., S. Omori, et al. 2002. MAP kinase in renal development. Nephrol. Dial. Transplant. 17(Suppl. 9):5–7.
  • Barisoni, L., L. A. Bruggeman, P. Mundel, V. D. D'Agati, and P. E. Klotman. 2000. HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. Kidney Int. 58:173–181.
  • Barisoni, L., W. Kriz, P. Mundel, and V. D'Agati. 1999. The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. J. Am. Soc. Nephrol. 10:51–61.
  • Bey, P., A. B. Gorostizaga, P. M. Maloberti, R. C. Lozano, C. Poderoso, F. C. Maciel, E. J. Podesta, and C. Paz. 2003. Adrenocorticotropin induces mitogen-activated protein kinase phosphatase 1 in Y1 mouse adrenocortical tumor cells. Endocrinology 144:1399–1406.
  • Bhalla, U. S., P. T. Ram, and R. Iyengar. 2002. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297:1018–1023.
  • Boute, N., O. Gribouval, S. Roselli, F. Benessy, H. Lee, A. Fuchshuber, K. Dahan, M. C. Gubler, P. Niaudet, and C. Antignac. 2000. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat. Genet. 24:349–354.
  • Brondello, J. M., A. Brunet, J. Pouyssegur, and F. R. McKenzie. 1997. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade. J. Biol. Chem. 272:1368–1376.
  • Canon, E., J. M. Cosgaya, S. Scsucova, and A. Aranda. 2004. Rapid effects of retinoic acid on CREB and ERK phosphorylation in neuronal cells. Mol. Biol. Cell 15:5583–5592.
  • Di Duca, M., R. Oleggini, S. Sanna-Cherchi, L. Pasquali, A. Di Donato, S. Parodi, R. Bertelli, G. Caridi, G. Frasca, G. Cerullo, A. Amoroso, F. P. Schena, F. Scolari, and G. M. Ghiggeri. 2006. Cis and trans regulatory elements in NPHS2 promoter: implications in proteinuria and progression of renal diseases. Kidney Int. 70:1332–1341.
  • Evans, T. R., and S. B. Kaye. 1999. Retinoids: present role and future potential. Br. J. Cancer 80:1–8.
  • Fujimori, K., and Y. Urade. 2007. Cooperative activation of lipocalin-type prostaglandin D synthase gene expression by activator protein-2β in proximal promoter and upstream stimulatory factor 1 within intron 4 in human brain-derived TE671 cells. Gene 397:143–152.
  • Gronemeyer, H., and R. Miturski. 2001. Molecular mechanisms of retinoid action. Cell. Mol. Biol. Lett. 6:3–52.
  • He, J. C., T.-C. Lu, M. Fleet, M. Sunamoto, M. Husain, W. Fang, S. Neves, Y. Chen, S. J. Shankland, R. Iyengar, and P. E. Klotman. 2007. Retinoic acid inhibits HIV-1 induced podocyte proliferation through the cAMP pathway. J. Am. Soc. Nephrol. 18:93–102.
  • He, J. C., M. Husain, M. Sunamoto, V. D. D'Agati, M. E. Klotman, R. Iyengar, and P. E. Klotman. 2004. Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. J. Clin. Investig. 114:643–651.
  • Hu, J. H., T. Chen, Z. H. Zhuang, L. Kong, M. C. Yu, Y. Liu, J. W. Zang, and B. X. Ge. 2007. Feedback control of MKP-1 expression by p38. Cell. Signal. 19:393–400.
  • Husain, M., G. L. Gusella, M. E. Klotman, I. H. Gelman, M. D. Ross, E. J. Schwartz, A. Cara, and P. E. Klotman. 2002. HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. J. Am. Soc. Nephrol. 13:1806–1815.
  • Juttner, S., T. Cramer, S. Wessler, A. Walduck, F. Gao, F. Schmitz, C. Wunder, M. Weber, S. M. Fischer, W. E. Schmidt, B. Wiedenmann, T. F. Meyer, M. Naumann, and M. Hocker. 2003. Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors. Cell. Microbiol. 5:821–834.
  • Kang, S. W., S. G. Adler, J. Lapage, and R. Natarajan. 2001. p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli. Kidney Int. 60:543–552.
  • Komers, R., J. N. Lindsley, et al. 2007. Renal p38 MAP kinase activity in experimental diabetes. Lab. Investig. 87:548–558.
  • Komulainen, K., M. Alanne, K. Auro, R. Kilpikari, P. Pajukanta, J. Saarela, P. Ellonen, K. Salminen, S. Kulathinal, K. Kuulasmaa, K. Silander, V. Salomaa, M. Perola, and L. Peltonen. 2006. Risk alleles of USF1 gene predict cardiovascular disease of women in two prospective studies. PLoS Genet. 2:e69.
  • Kwak, S. P., D. J. Hakes, K. J. Martell, and J. E. Dixon. 1994. Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene. J. Biol. Chem. 269:3596–3604.
  • Lee, T. I., S. E. Johnstone, and R. A. Young. 2006. Chromatin immunoprecipitation and microarray-based analysis of protein location. Nat. Protoc. 1:729–748.
  • Lehrke, I., M. Schaier, K. Schade, C. Morath, R. Waldherr, E. Ritz, and J. Wagner. 2002. Retinoid receptor-specific agonists alleviate experimental glomerulonephritis. Am. J. Physiol. (Renal Physiol.) 282:F741–F751.
  • Li, J., M. Gorospe, D. Hutter, J. Barnes, S. M. Keyse, and Y. Liu. 2001. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. Mol. Cell. Biol. 21:8213–8224.
  • Licht, J. D., and A. Zelent. 2005. Retinoid and growth factor receptor signaling in APL. Blood 105:1381–1382.
  • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25:402–408.
  • Lonze, B. E., and D. D. Ginty. 2002. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35:605–623.
  • Moreno-Manzano, V., F. Mampaso, J. C. Sepulveda-Munoz, M. Alique, S. Chen, F. N. Ziyadeh, M. C. Iglesias-de la Cruz, J. Rodriguez, E. Nieto, J. M. Orellana, P. Reyes, I. Arribas, Q. Xu, M. Kitamura, and F. J. Lucio Cazana. 2003. Retinoids as a potential treatment for experimental puromycin-induced nephrosis. Br. J. Pharmacol. 139:823–831.
  • Oleggini, R., R. Bertelli, A. Di Donato, M. Di Duca, G. Caridi, S. Sanna-Cherchi, F. Scolari, L. Murer, L. Allegri, R. Coppo, F. Emma, G. Camussi, F. Perfumo, and G. M. Ghiggeri. 2006. Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic syndrome. Gene Expr. 13:59–66.
  • Omori, S., M. Hida, et al. 2002. Expression of mitogen-activated protein kinase family in rat renal development. Kidney Int. 58:27–37.
  • Palm-Leis, A., U. S. Singh, B. S. Herbelin, G. D. Olsovsky, K. M. Baker, and J. Pan. 2004. Mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases mediate the inhibitory effects of all-trans retinoic acid on the hypertrophic growth of cardiomyocytes. J. Biol. Chem. 279:54905–54917.
  • Renault, M. A., S. Jalvy, M. Potier, I. Belloc, E. Genot, L. V. Dekker, C. Desgranges, and A. P. Gadeau. 2005. UTP induces osteopontin expression through a coordinate action of NFκB, activator protein-1, and upstream stimulatory factor in arterial smooth muscle cells. J. Biol. Chem. 280:2708–2713.
  • Ryser, S., A. Massiha, I. Piuz, and W. Schlegel. 2004. Stimulated initiation of mitogen-activated protein kinase phosphatase-1 (MKP-1) gene transcription involves the synergistic action of multiple cis-acting elements in the proximal promoter. Biochem. J. 378:473–484.
  • Saleem, M. A., M. J. O'Hare, J. Reiser, R. J. Coward, C. D. Inward, T. Farren, C. Y. Xing, L. Ni, P. W. Mathieson, and P. Mundel. 2002. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J. Am. Soc. Nephrol. 13:630–638.
  • Simonson, M. S. 1994. Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells. Am. J. Physiol. 267:F805–F815.
  • Skaggs, H. S., H. Xing, D. C. Wilkerson, L. A. Murphy, Y. Hong, C. N. Mayhew, and K. D. Sarge. 2007. HSF1-TPR interaction facilitates export of stress-induced HSP70 mRNA. J. Biol. Chem. 282:33902–33907.
  • Sunamoto, M., M. Husain, J. C. He, E. J. Schwartz, and P. E. Klotman. 2003. Critical role for Nef in HIV-1-induced podocyte dedifferentiation. Kidney Int. 64:1695–1701.
  • Tabuchi, A., H. Sakaya, T. Kisukeda, H. Fushiki, and M. Tsuda. 2002. Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I. J. Biol. Chem. 277:35920–35931.
  • Valledor, A. F., J. Xaus, M. Comalada, C. Soler, and A. Celada. 2000. Protein kinase C epsilon is required for the induction of mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J. Immunol. 164:29–37.
  • Wagner, J., C. Dechow, C. Morath, I. Lehrke, K. Amann, R. Waldherr, J. Floege, and E. Ritz. 2000. Retinoic acid reduces glomerular injury in a rat model of glomerular damage. J. Am. Soc Nephrol. 11:1479–1487.
  • Wahab, N., D. Cox, et al. 2007. Connective tissue growth factor (CTGF) promotes activated mesangial cell survival via up-regulation of mitogen-activated protein kinase phosphatase-1 (MKP-1). Biochem. J. 406:131–138.
  • Winston, J. A., G. C. Burns, and P. E. Klotman. 1998. The human immunodeficiency virus (HIV) epidemic and HIV-associated nephropathy. Semin. Nephrol. 18:373–377.
  • Xu, Q., T. Konta, A. Furusu, K. Nakayama, J. Lucio-Cazana, L. G. Fine, and M. Kitamura. 2002. Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect. J. Biol. Chem. 277:41693–41700.
  • Zhao, Q., J. Tao, Q. Zhu, P. M. Jia, A. X. Dou, X. Li, F. Cheng, S. Waxman, G. Q. Chen, S. J. Chen, M. Lanotte, Z. Chen, and J. H. Tong. 2004. Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation. Leukemia 18:285–292.
  • Zhao, Q., X. Wang, L. D. Nelin, Y. Yao, R. Matta, M. E. Manson, R. S. Baliga, X. Meng, C. V. Smith, J. A. Bauer, C. H. Chang, and Y. Liu. 2006. MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J. Exp. Med. 203:131–140.

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