REFERENCES
- Arnett, K. L., et al. 2010. Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat. Struct. Mol. Biol. 17:1312–1317.
- Artavanis-Tsakonas, S., M. D. Rand, and R. J. Lake. 1999. Notch signaling: cell fate control and signal integration in development. Science 284:770–776.
- Aster, J. C., and W. S. Pear. 2001. Notch signaling in leukemia. Curr. Opin. Hematol. 8:237–244.
- Aster, J. C., et al. 2000. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell. Biol. 20:7505–7515.
- Bellavia, D., et al. 2000. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19:3337–3348.
- Capobianco, A. J., P. Zagouras, C. M. Blaumueller, S. Artavanis-Tsakonas, and J. M. Bishop. 1997. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell. Biol. 17:6265–6273.
- Chu, J., and E. H. Bresnick. 2004. Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1. J. Biol. Chem. 279:12337–12345.
- Dahl, R., B. Wani, and M. J. Hayman. 1998. The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42. Oncogene 16:1579–1586.
- Demarest, R. M., F. Ratti, and A. J. Capobianco. 2008. It's T-ALL about Notch. Oncogene 27:5082–5091.
- Ehebauer, M. T., D. Y. Chirgadze, P. Hayward, A. Martinez Arias, and T. L. Blundell. 2005. High-resolution crystal structure of the human Notch 1 ankyrin domain. Biochem. J. 392:13–20.
- Ellisen, L. W., et al. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649–661.
- Friedmann, D. R., J. J. Wilson, and R. A. Kovall. 2008. RAM-induced allostery facilitates assembly of a notch pathway active transcription complex. J. Biol. Chem. 283:14781–14791.
- Fryer, C. J., J. B. White, and K. A. Jones. 2004. Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16:509–520.
- Gallahan, D., and R. Callahan. 1997. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene 14:1883–1890.
- Jeffries, S., and A. J. Capobianco. 2000. Neoplastic transformation by Notch requires nuclear localization. Mol. Cell. Biol. 20:3928–3941.
- Jeffries, S., D. J. Robbins, and A. J. Capobianco. 2002. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell. Biol. 22:3927–3941.
- Kovall, R. A., and W. A. Hendrickson. 2004. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. EMBO J. 23:3441–3451.
- Kurooka, H., K. Kuroda, and T. Honjo. 1998. Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region. Nucleic Acids Res. 26:5448–5455.
- Leong, G. M., et al. 2004. Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300. Biochem. Biophys. Res. Commun. 315:1070–1076.
- Lin, S. E., T. Oyama, T. Nagase, K. Harigaya, and M. Kitagawa. 2002. Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling. J. Biol. Chem. 277:50612–50620.
- Lubman, O. Y., M. X. Ilagan, R. Kopan, and D. Barrick. 2007. Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch. J. Mol. Biol. 365:577–589.
- Lubman, O. Y., R. Kopan, G. Waksman, and S. Korolev. 2005. The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold. Protein Sci. 14:1274–1281.
- Miele, L., and B. Osborne. 1999. Arbiter of differentiation and death: Notch signaling meets apoptosis. J. Cell. Physiol. 181:393–409.
- Milner, L. A., and A. Bigas. 1999. Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. Blood 93:2431–2448.
- Nam, Y., P. Sliz, W. S. Pear, J. C. Aster, and S. C. Blacklow. 2007. Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Proc. Natl. Acad. Sci. U. S. A. 104:2103–2108.
- Nam, Y., P. Sliz, L. Song, J. C. Aster, and S. C. Blacklow. 2006. Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124:973–983.
- Nam, Y., A. P. Weng, J. C. Aster, and S. C. Blacklow. 2003. Structural requirements for assembly of the CSL. intracellular Notch1.Mastermind-like 1 transcriptional activation complex. J. Biol. Chem. 278:21232–21239.
- Nye, J. S., R. Kopan, and R. Axel. 1994. An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development 120:2421–2430.
- Oswald, F., et al. 2002. SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J. 21:5417–5426.
- Petcherski, A. G., and J. Kimble. 2000. Mastermind is a putative activator for Notch. Curr. Biol. 10:R471–R473.
- Robbins, J., B. J. Blondel, D. Gallahan, and R. Callahan. 1992. Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J. Virol. 66:2594–2599.
- Ronchini, C., and A. J. Capobianco. 2001. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Mol. Cell. Biol. 21:5925–5934.
- Tani, S., H. Kurooka, T. Aoki, N. Hashimoto, and T. Honjo. 2001. The N- and C-terminal regions of RBP-J. interact with the ankyrin repeats of Notch1 RAMIC to activate transcription. Nucleic Acids Res. 29:1373–1380.
- Wallberg, A. E., K. Pedersen, U. Lendahl, and R. G. Roeder. 2002. p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol. Cell. Biol. 22:7812–7819.
- Weng, A. P., et al. 2003. Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23:655–664.
- Wilson, J. J., and R. A. Kovall. 2006. Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell 124:985–996.
- Wu, L., et al. 2000. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 26:484–489.
- Wu, L., T. Sun, K. Kobayashi, P. Gao, and J. D. Griffin. 2002. Identification of a family of mastermind-like transcriptional coactivators for mammalian Notch receptors. Mol. Cell. Biol. 22:7688–7700.
- Zhou, S., et al. 2000. SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol. Cell. Biol. 20:2400–2410.
- Zweifel, M. E., D. J. Leahy, F. M. Hughson, and D. Barrick. 2003. Structure and stability of the ankyrin domain of the Drosophila Notch receptor. Protein Sci. 12:2622–2632.