Drosophila Lin-52 Acts in Opposition to Repressive Components of the Myb-MuvB/dREAM Complex

REFERENCES

• Andrejka L, et al. 2011. Animal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex. Proc. Natl. Acad. Sci. U. S. A. 108:17438–17443.
   PubMedGoogle Scholar
• Beall EL, Bell M, Georlette D, Botchan MR. 2004. Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication. Genes Dev. 18:1667–1680.
   PubMedGoogle Scholar
• Beall EL, et al. 2007. Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. Genes Dev. 21:904–919.
   PubMed Web of Science ®Google Scholar
• Beall EL, et al. 2002. Role for a Drosophila Myb-containing protein complex in site-specific DNA replication. Nature 420:833–837.
   PubMedGoogle Scholar
• Ceol CJ, Stegmeier F, Harrison MM, Horvitz HR. 2006. Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development. Genetics 173:709–726.
   PubMed Web of Science ®Google Scholar
• Chou TB, Perrimon N. 1992. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131:643–653.
   PubMed Web of Science ®Google Scholar
• Doggett K, Jiang J, Aleti G, White-Cooper H. 2011. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. Dev. Biol. 355:381–393.
   PubMedGoogle Scholar
• Ferguson EL, Horvitz HR. 1989. The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Genetics 123:109–121.
   PubMedGoogle Scholar
• Fung SM, Ramsay G, Katzen AL. 2002. Mutations in Drosophila myb lead to centrosome amplification and genomic instability. Development 129:347–359.
   PubMed Web of Science ®Google Scholar
• Georlette D, et al. 2007. Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells. Genes Dev. 21:2880–2896.
   PubMed Web of Science ®Google Scholar
• Golic KG. 1991. Site-specific recombination between homologous chromosomes in Drosophila. Science 252:958–961.
   PubMed Web of Science ®Google Scholar
• Goshima G, et al. 2007. Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316:417–421.
   PubMed Web of Science ®Google Scholar
• Greenspan RJ. 1997. Fly pushing: the theory and practice of Drosophila genetics. Cold Spring Harbor Laboratory Press, Plainview, NY.
   Google Scholar
• Harrison MM, Ceol CJ, Lu X, Horvitz HR. 2006. Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex. Proc. Natl. Acad. Sci. U. S. A. 103:16782–16787.
   PubMed Web of Science ®Google Scholar
• Hou DX, Akimaru H, Ishii S. 1997. Trans-activation by the Drosophila myb gene product requires a Drosophila homologue of CBP. FEBS Lett. 413:60–64.
   PubMedGoogle Scholar
• Jiang J, Benson E, Bausek N, Doggett K, White-Cooper H. 2007. Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early. Development 134:1549–1559.
   PubMedGoogle Scholar
• Korenjak M, et al. 2004. Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell 119:181–193.
   PubMed Web of Science ®Google Scholar
• Lewis PW, et al. 2004. Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev. 18:2929–2940.
   PubMed Web of Science ®Google Scholar
• Lipsick JS. 2004. synMuv verite–Myb comes into focus. Genes Dev. 18:2837–2844.
   PubMedGoogle Scholar
• Litovchick L, Florens LA, Swanson SK, Washburn MP, DeCaprio JA. 2011. DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly. Genes Dev. 25:801–813.
   PubMed Web of Science ®Google Scholar
• Litovchick L, et al. 2007. Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol. Cell 26:539–551.
   PubMed Web of Science ®Google Scholar
• Manak JR, Mitiku N, Lipsick JS. 2002. Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability. Proc. Natl. Acad. Sci. U. S. A. 99:7438–7443.
   PubMed Web of Science ®Google Scholar
• Manak JR, Wen H, Tran V, Andrejka L, Lipsick JS. 2007. Loss of Drosophila Myb interrupts the progression of chromosome condensation. Nat. Cell Biol. 9:581–587.
   PubMed Web of Science ®Google Scholar
• Okada M, Akimaru H, Hou DX, Takahashi T, Ishii S. 2002. Myb controls G(2)/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc. EMBO J. 21:675–684.
   PubMedGoogle Scholar
• Pilkinton M, Sandoval R, Colamonici OR. 2007. Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex. Oncogene 26:7535–7543.
   PubMed Web of Science ®Google Scholar
• Ready DF, Hanson TE, Benzer S. 1976. Development of the Drosophila retina, a neurocrystalline lattice. Dev. Biol. 53:217–240.
   PubMed Web of Science ®Google Scholar
• Schmit F, et al. 2007. LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes. Cell Cycle 6:1903–1913.
   PubMed Web of Science ®Google Scholar
• Simon MA, Bowtell DDL, Dodson GS, Laverty TR, Rubin GM. 1991. Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67:701–716.
   PubMedGoogle Scholar
• Somma MP, et al. 2008. Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. PLoS Genet. 4:e1000126. https://doi.org/10.1371/journal.pgen.1000126.
   PubMed Web of Science ®Google Scholar
• Stevaux O, et al. 2002. Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J. 21:4927–4937.
   PubMedGoogle Scholar
• Stowers RS, Schwarz TL. 1999. A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. Genetics 152:1631–1639.
   PubMedGoogle Scholar
• Tabuchi TM, et al. 2011. Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex. PLoS Genet. 7:e1002074. https://doi.org/10.1371/journal.pgen.1002074.
   PubMed Web of Science ®Google Scholar
• Thomas JH, Ceol CJ, Schwartz HT, Horvitz HR. 2003. New genes that interact with lin-35 Rb to negatively regulate the let-60 ras pathway in Caenorhabditis elegans. Genetics 164:135–151.
   Google Scholar
• Tschop K, et al. 2011. A kinase shRNA screen links LATS2 and the pRB tumor suppressor. Genes Dev. 25:814–830.
   PubMed Web of Science ®Google Scholar
• Wen H, Andrejka L, Ashton J, Karess R, Lipsick JS. 2008. Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev. 22:601–614.
   PubMed Web of Science ®Google Scholar
• White-Cooper H. 2010. Molecular mechanisms of gene regulation during Drosophila spermatogenesis. Reproduction 139:11–21.
   PubMed Web of Science ®Google Scholar
• White-Cooper H, Leroy D, MacQueen A, Fuller MT. 2000. Transcription of meiotic cell cycle and terminal differentiation genes depends on a conserved chromatin associated protein, whose nuclear localisation is regulated. Development 127:5463–5473.
   PubMedGoogle Scholar