REFERENCES
- Bunn PAJr. 2012. Worldwide overview of the current status of lung cancer diagnosis and treatment. Arch. Pathol. Lab. Med. 136:1478–1481. http://dx.doi.org/10.5858/arpa.2012-0295-SA.
- Gottschling S, Schnabel PA, Herth FJ, Herpel E. 2012. Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer. Cancer Genomics Proteomics 9:275–286. http://cgp.iiarjournals.org/content/9/5/275.long.
- Jiang W, Peng J, Zhang Y, Cho WC, Jin K. 2012. The implications of cancer stem cells for cancer therapy. Int. J. Mol. Sci. 13:16636–16657. http://dx.doi.org/10.3390/ijms131216636.
- Wu X, Chen H, Wang X. 2012. Can lung cancer stem cells be targeted for therapies? Cancer Treat. Rev. 38:580–588. http://dx.doi.org/10.1016/j.ctrv.2012.02.013.
- Tirino V, Desiderio V, Paino F, De Rosa A, Papaccio F, La Noce M, Laino L, De Francesco F, Papaccio G. 2013. Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization. FASEB J. 27:13–24. http://dx.doi.org/10.1096/fj.12-218222.
- Marjanovic ND, Weinberg RA, Chaffer CL. 2013. Cell plasticity and heterogeneity in cancer. Clin. Chem. 59:168–179. http://dx.doi.org/10.1373/clinchem.2012.184655.
- Baccelli I, Trumpp A. 2012. The evolving concept of cancer and metastasis stem cells. J. Cell Biol. 198:281–293. http://dx.doi.org/10.1083/jcb.201202014.
- Tang DG. 2012. Understanding cancer stem cell heterogeneity and plasticity. Cell Res. 22:457–472. http://dx.doi.org/10.1038/cr.2012.13.
- Bergfeld SA, DeClerck YA. 2010. Bone marrow-derived mesenchymal stem cells and the tumor microenvironment. Cancer Metastasis Rev. 29:249–261. http://dx.doi.org/10.1007/s10555-010-9222-7.
- Keating A. 2012. Mesenchymal stromal cells: new directions. Cell Stem Cell 10:709–716. http://dx.doi.org/10.1016/j.stem.2012.05.015.
- Klopp AH, Gupta A, Spaeth E, Andreeff M, Marini F3rd. 2011. Concise review. Dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth? Stem Cells 29:11–19. http://dx.doi.org/10.1002/stem.559.
- Torsvik A, Bjerkvig R. 2013. Mesenchymal stem cell signaling in cancer progression. Cancer Treat. Rev. 39:180–188. http://dx.doi.org/10.1016/j.ctrv.2012.03.005.
- Kanehira M, Kikuchi T, Ohkouchi S, Shibahara T, Tode N, Santoso A, Daito H, Ohta H, Tamada T, Nukiwa T. 2012. Targeting lysophosphatidic acid signaling retards culture-associated senescence of human marrow stromal cells. PLoS One 7:e32185. http://dx.doi.org/10.1371/journal.pone.0032185.
- Zaini J, Andarini S, Tahara M, Saijo Y, Ishii N, Kawakami K, Taniguchi M, Sugamura K, Nukiwa T, Kikuchi T. 2007. OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice. J. Clin. Invest. 117:3330–3338. http://dx.doi.org/10.1172/JCI32693.
- Mafi P, Hindocha S, Mafi R, Griffin M, Khan WS. 2011. Adult mesenchymal stem cells and cell surface characterization—a systematic review of the literature. Open Orthop. J. 5:253–260. http://dx.doi.org/10.2174/1874325001105010253.
- Nery AA, Nascimento IC, Glaser T, Bassaneze V, Krieger JE, Ulrich H. 2013. Human mesenchymal stem cells: from immunophenotyping by flow cytometry to clinical applications. Cytometry A 83:48–61. http://dx.doi.org/10.1002/cyto.a.22205.
- Metzger RJ, Krasnow MA. 1999. Genetic control of branching morphogenesis. Science 284:1635–1639. http://dx.doi.org/10.1126/science.284.5420.1635.
- Warburton D, Schwarz M, Tefft D, Flores-Delgado G, Anderson KD, Cardoso WV. 2000. The molecular basis of lung morphogenesis. Mech. Dev. 92:55–81. http://dx.doi.org/10.1016/S0925-4773(99)00325-1.
- Maugeri-Sacca M, Vigneri P, De Maria R. 2011. Cancer stem cells and chemosensitivity. Clin. Cancer Res. 17:4942–4947. http://dx.doi.org/10.1158/1078-0432.CCR-10-2538.
- Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. 2004. A distinct “side population” of cells with high drug efflux capacity in human tumor cells. Proc. Natl. Acad. Sci. U. S. A. 101:14228–14233. http://dx.doi.org/10.1073/pnas.0400067101.
- Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP. 2008. PML targeting eradicates quiescent leukaemia-initiating cells. Nature 453:1072–1078. http://dx.doi.org/10.1038/nature07016.
- Saito Y, Uchida N, Tanaka S, Suzuki N, Tomizawa-Murasawa M, Sone A, Najima Y, Takagi S, Aoki Y, Wake A, Taniguchi S, Shultz LD, Ishikawa F. 2010. Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML. Nat. Biotechnol. 28:275–280. http://dx.doi.org/10.1038/nbt.1607.
- de The H, Chen Z. 2010. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure. Nat. Rev. Cancer 10:775–783. http://dx.doi.org/10.1038/nrc2943.
- Masetti R, Biagi C, Zama D, Vendemini F, Martoni A, Morello W, Gasperini P, Pession A. 2012. Retinoids in pediatric onco-hematology: the model of acute promyelocytic leukemia and neuroblastoma. Adv. Ther. 29:747–762. http://dx.doi.org/10.1007/s12325-012-0047-3.
- Beenken A, Mohammadi M. 2009. The FGF family: biology, pathophysiology and therapy. Nat. Rev. Drug Discov. 8:235–253. http://dx.doi.org/10.1038/nrd2792.
- Goetz R, Mohammadi M. 2013. Exploring mechanisms of FGF signalling through the lens of structural biology. Nat. Rev. Mol. Cell Biol. 14:166–180. http://dx.doi.org/10.1038/nrm3528.
- Miraoui H, Marie PJ. 2010. Fibroblast growth factor receptor signaling crosstalk in skeletogenesis. Sci. Signal. 3:re9. http://dx.doi.org/10.1126/scisignal.3146re9.
- Acevedo VD, Ittmann M, Spencer DM. 2009. Paths of FGFR-driven tumorigenesis. Cell Cycle 8:580–588. http://dx.doi.org/10.4161/cc.8.4.7657.
- Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. 2010. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc. Natl. Acad. Sci. U. S. A. 107:21737–21742. http://dx.doi.org/10.1073/pnas.1007863107.
- Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z. 2012. Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation. Am. J. Pathol. 180:1928–1941. http://dx.doi.org/10.1016/j.ajpath.2012.01.020.
- Min H, Danilenko DM, Scully SA, Bolon B, Ring BD, Tarpley JE, DeRose M, Simonet WS. 1998. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 12:3156–3161. http://dx.doi.org/10.1101/gad.12.20.3156.
- Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, Yagishita N, Matsui D, Koga Y, Itoh N, Kato S. 1999. Fgf10 is essential for limb and lung formation. Nat. Genet. 21:138–141. http://dx.doi.org/10.1038/5096.
- Alderson R, Gohari-Fritsch S, Olsen H, Roschke V, Vance C, Connolly K. 2002. In vitro and in vivo effects of repifermin (keratinocyte growth factor-2, KGF-2) on human carcinoma cells. Cancer Chemother. Pharmacol. 50:202–212. http://dx.doi.org/10.1007/s00280-002-0493-8.
- Clark JC, Tichelaar JW, Wert SE, Itoh N, Perl AK, Stahlman MT, Whitsett JA. 2001. FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am. J. Physiol. Lung Cell. Mol. Physiol. 280:L705–L715. http://ajplung.physiology.org/content/280/4/L705.
- El Agha E, Herold S, Al Alam D, Quantius J, MacKenzie B, Carraro G, Moiseenko A, Chao CM, Minoo P, Seeger W, Bellusci S. 2014. Fgf10-positive cells represent a progenitor cell population during lung development and postnatally. Development 141:296–306. http://dx.doi.org/10.1242/dev.099747.