Early Embryonic Lethality of Mice Lacking the Essential Protein SNEV

REFERENCES

• Ajuh, P., B. Kuster, K. Panov, J. C. Zomerdijk, M. Mann, and A. I. Lamond. 2000. Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. EMBO J. 19:6569–6581.
   PubMed Web of Science ®Google Scholar
• Blalock, E. M., J. W. Geddes, K. C. Chen, N. M. Porter, W. R. Markesbery, and P. W. Landfield. 2004. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc. Natl. Acad. Sci. USA 101:2173–2178.
   PubMed Web of Science ®Google Scholar
• Bohr, V. A. 2005. Deficient DNA repair in the human progeroid disorder, Werner syndrome. Mutat. Res. 577:252–259.
   PubMedGoogle Scholar
• Burckin, T., R. Nagel, Y. Mandel-Gutfreund, L. Shiue, T. A. Clark, J. L. Chong, T. H. Chang, S. Squazzo, G. Hartzog, and M. Ares, Jr. 2005. Exploring functional relationships between components of the gene expression machinery. Nat. Struct. Mol. Biol. 12:175–182.
   PubMed Web of Science ®Google Scholar
• Chan, S. P., and S. C. Cheng. 2005. The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation. J. Biol. Chem. 280:31190–31199.
   PubMedGoogle Scholar
• Chan, S. P., D. I. Kao, W. Y. Tsai, and S. C. Cheng. 2003. The Prp19p-associated complex in spliceosome activation. Science 302:279–282.
   PubMed Web of Science ®Google Scholar
• Cho, S. Y., E. S. Shin, P. J. Park, D. W. Shin, H. K. Chang, D. Kim, H. H. Lee, J. H. Lee, S. H. Kim, M. J. Song, I. S. Chang, O. S. Lee, and T. R. Lee. 2007. Identification of mouse Prp19p as a lipid droplet-associated protein and its possible involvement in the biogenesis of lipid droplets. J. Biol. Chem. 282:2456–2465.
   PubMedGoogle Scholar
• Frazer, K. A., L. Pachter, A. Poliakov, E. M. Rubin, and I. Dubchak. 2004. VISTA: computational tools for comparative genomics. Nucleic Acids Res. 32:W273–W279.
   PubMed Web of Science ®Google Scholar
• Gonczy, P., C. Echeverri, K. Oegema, A. Coulson, S. J. Jones, R. R. Copley, J. Duperon, J. Oegema, M. Brehm, E. Cassin, E. Hannak, M. Kirkham, S. Pichler, K. Flohrs, A. Goessen, S. Leidel, A. M. Alleaume, C. Martin, N. Ozlu, P. Bork, and A. A. Hyman. 2000. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408:331–336.
   PubMed Web of Science ®Google Scholar
• Gornemann, J., K. M. Kotovic, K. Hujer, and K. M. Neugebauer. 2005. Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex. Mol. Cell 19:53–63.
   PubMed Web of Science ®Google Scholar
• Gotzmann, J., C. Gerner, M. Meissner, K. Holzmann, R. Grimm, W. Mikulits, and G. Sauermann. 2000. hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions. Exp. Cell Res. 261:166–179.
   PubMedGoogle Scholar
• Grey, M., A. Dusterhoft, J. A. Henriques, and M. Brendel. 1996. Allelism of PSO4 and PRP19 links pre-mRNA processing with recombination and error-prone DNA repair in Saccharomyces cerevisiae. Nucleic Acids Res. 24:4009–4014.
   PubMed Web of Science ®Google Scholar
• Grillari, J., P. Ajuh, G. Stadler, M. Löscher, R. Voglauer, W. Ernst, J. Chusainow, F. Eisenhaber, M. Pokar, K. Fortschegger, M. Grey, A. I. Lamond, and H. Katinger. 2005. SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. Nucleic Acids Res. 33:6868–6883.
   PubMedGoogle Scholar
• Grillari, J., O. Hohenwarter, R. M. Grabherr, and H. Katinger. 2000. Subtractive hybridization of mRNA from early passage and senescent endothelial cells. Exp. Gerontol. 35:187–197.
   PubMed Web of Science ®Google Scholar
• Grillari, J., H. Katinger, and R. Voglauer. 2006. Aging and the ubiquitinome: traditional and non-traditional functions of ubiquitin in aging cells and tissues. Exp. Gerontol. 41:1067–1079.
   PubMedGoogle Scholar
• Hamatani, T., M. G. Carter, A. A. Sharov, and M. S. Ko. 2004. Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell 6:117–131.
   PubMed Web of Science ®Google Scholar
• Hatakeyama, S., M. Yada, M. Matsumoto, N. Ishida, and K. I. Nakayama. 2001. U box proteins as a new family of ubiquitin-protein ligases. J. Biol. Chem. 276:33111–33120.
   PubMedGoogle Scholar
• Huang, T. T., and A. D. D'Andrea. 2006. Regulation of DNA repair by ubiquitylation. Nat. Rev. Mol. Cell Biol. 7:323–334.
   PubMed Web of Science ®Google Scholar
• Jumaa, H., G. Wei, and P. J. Nielsen. 1999. Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Curr. Biol. 9:899–902.
   PubMed Web of Science ®Google Scholar
• Jurica, M. S., and M. J. Moore. 2003. Pre-mRNA splicing: awash in a sea of proteins. Mol. Cell 12:5–14.
   PubMed Web of Science ®Google Scholar
• Kamath, R. S., A. G. Fraser, Y. Dong, G. Poulin, R. Durbin, M. Gotta, A. Kanapin, N. Le Bot, S. Moreno, M. Sohrmann, D. P. Welchman, P. Zipperlen, and J. Ahringer. 2003. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421:231–237.
   PubMed Web of Science ®Google Scholar
• Kortlever, R. M., P. J. Higgins, and R. Bernards. 2006. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat. Cell Biol. 8:877–884.
   PubMed Web of Science ®Google Scholar
• Krishnamurthy, J., C. Torrice, M. R. Ramsey, G. I. Kovalev, K. Al-Regaiey, L. Su, and N. E. Sharpless. 2004. Ink4a/Arf expression is a biomarker of aging. J. Clin. Investig. 114:1299–1307.
   PubMed Web of Science ®Google Scholar
• Löscher, M., K. Fortschegger, G. Ritter, M. Wostry, R. Voglauer, J. A. Schmid, S. Watters, A. J. Rivett, P. Ajuh, A. I. Lamond, H. Katinger, and J. Grillari. 2005. Interaction of U-box E3 ligase SNEV with PSMB4, the β7 subunit of the 20 S proteasome. Biochem. J. 388:593–603.
   PubMedGoogle Scholar
• Mahajan, K. N., and B. S. Mitchell. 2003. Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase. Proc. Natl. Acad. Sci. USA 100:10746–10751.
   PubMedGoogle Scholar
• Makarova, O. V., E. M. Makarov, H. Urlaub, C. L. Will, M. Gentzel, M. Wilm, and R. Luhrmann. 2004. A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J. 23:2381–2391.
   PubMed Web of Science ®Google Scholar
• Mansour, S. L., K. R. Thomas, and M. R. Capecchi. 1988. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 336:348–352.
   PubMed Web of Science ®Google Scholar
• Milchanowski, A. B., A. L. Henkenius, M. Narayanan, V. Hartenstein, and U. Banerjee. 2004. Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis. Genetics 168:325–339.
   PubMed Web of Science ®Google Scholar
• Nagy, A., M. Gertsenstein, K. Vintersten, and R. Behringer. 2003. Manipulating the mouse embryo: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
   Google Scholar
• Ohi, M. D., and K. L. Gould. 2002. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8:798–815.
   PubMedGoogle Scholar
• Ohi, M. D., C. W. Vander Kooi, J. A. Rosenberg, L. Ren, J. P. Hirsch, W. J. Chazin, T. Walz, and K. L. Gould. 2005. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol. Cell. Biol. 25:451–460.
   PubMedGoogle Scholar
• O'Keefe, R. T., A. Mayeda, C. L. Sadowski, A. R. Krainer, and D. L. Spector. 1994. Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J. Cell Biol. 124:249–260.
   PubMed Web of Science ®Google Scholar
• Parrinello, S., E. Samper, A. Krtolica, J. Goldstein, S. Melov, and J. Campisi. 2003. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat. Cell Biol. 5:741–747.
   PubMed Web of Science ®Google Scholar
• Sibilia, M., and E. F. Wagner. 1995. Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269:234–238.
   PubMed Web of Science ®Google Scholar
• Smith, T. F., C. Gaitatzes, K. Saxena, and E. J. Neer. 1999. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 24:181–185.
   PubMed Web of Science ®Google Scholar
• Tanackovic, G., and A. Kramer. 2005. Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo. Mol. Biol. Cell 16:1366–1377.
   PubMed Web of Science ®Google Scholar
• Todaro, G. J., and H. Green. 1963. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17:299–313.
   PubMed Web of Science ®Google Scholar
• Urano, Y., M. Iiduka, A. Sugiyama, H. Akiyama, K. Uzawa, G. Matsumoto, Y. Kawasaki, and F. Tashiro. 2006. Involvement of the mouse Prp19 gene in neuronal/astroglial cell fate decisions. J. Biol. Chem. 281:7498–7514.
   PubMedGoogle Scholar
• Voglauer, R., M. W. Chang, B. Dampier, M. Wieser, K. Baumann, T. Sterovsky, M. Schreiber, H. Katinger, and J. Grillari. 2006. SNEV overexpression extends the life span of human endothelial cells. Exp. Cell Res. 312:746–759.
   PubMedGoogle Scholar
• Wang, B. B., and V. Brendel. 2004. The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing. Genome Biol. 5:R102.
   PubMedGoogle Scholar
• Wang, H. Y., X. Xu, J. H. Ding, J. R. Bermingham, Jr., and X. D. Fu. 2001. SC35 plays a role in T cell development and alternative splicing of CD45. Mol. Cell 7:331–342.
   PubMed Web of Science ®Google Scholar
• Wang, J., Y. Takagaki, and J. L. Manley. 1996. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes Dev. 10:2588–2599.
   PubMedGoogle Scholar
• Zeng, F., D. A. Baldwin, and R. M. Schultz. 2004. Transcript profiling during preimplantation mouse development. Dev. Biol. 272:483–496.
   PubMed Web of Science ®Google Scholar
• Zhang, N., R. Kaur, X. Lu, X. Shen, L. Li, and R. J. Legerski. 2005. The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J. Biol. Chem. 280:40559–40567.
   PubMedGoogle Scholar