p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

REFERENCES

• Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell 124:783–801.
   PubMed Web of Science ®Google Scholar
• Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413:732–738.
   PubMed Web of Science ®Google Scholar
• Anzola, M., and J. J. Burgos. 2003. Hepatocellular carcinoma: molecular interactions between hepatitis C virus and p53 in hepatocarcinogenesis. Expert Rev. Mol. Med. 5:1–16.
   PubMedGoogle Scholar
• Atencia, R., F. J. Bustamante, A. Valdivieso, A. Arrieta, M. Rinon, A. Prada, and N. Maruri. 2007. Differential expression of viral PAMP receptors mRNA in peripheral blood of patients with chronic hepatitis C infection. BMC Infect. Dis. 7:136.
   PubMed Web of Science ®Google Scholar
• Castedo, M., J. L. Perfettini, M. Piacentini, and G. Kroemer. 2005. p53—a pro-apoptotic signal transducer involved in AIDS. Biochem. Biophys. Res. Commun. 331:701–706.
   PubMed Web of Science ®Google Scholar
• Collot-Teixeira, S., J. Bass, F. Denis, and S. Ranger-Rogez. 2004. Human tumor suppressor p53 and DNA viruses. Rev. Med. Virol. 14:301–319.
   PubMedGoogle Scholar
• Dharel, N., N. Kato, R. Muroyama, H. Taniguchi, M. Otsuka, Y. Wang, A. Jazag, R. X. Shao, J. H. Chang, M. K. Adler, T. Kawabe, and M. Omata. 2008. Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus. Hepatology 47:1136–1149.
   PubMedGoogle Scholar
• Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529–1531.
   PubMed Web of Science ®Google Scholar
• Djelloul, S., M. E. Forgue-Lafitte, B. Hermelin, M. Mareel, E. Bruyneel, A. Baldi, A. Giordano, E. Chastre, and C. Gespach. 1997. Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products. FEBS Lett. 406:234–242.
   PubMed Web of Science ®Google Scholar
• Forbes, S., J. Clements, E. Dawson, S. Bamford, T. Webb, A. Dogan, A. Flanagan, J. Teague, R. Wooster, P. A. Futreal, and M. R. Stratton. 2006. Cosmic 2005. Br. J. Cancer 94:318–322.
   PubMed Web of Science ®Google Scholar
• Furrie, E., S. Macfarlane, G. Thomson, and G. T. Macfarlane. 2005. Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria. Immunology 115:565–574.
   PubMed Web of Science ®Google Scholar
• Gale, M., Jr., and E. M. Foy. 2005. Evasion of intracellular host defence by hepatitis C virus. Nature 436:939–945.
   PubMed Web of Science ®Google Scholar
• Gitlin, L., W. Barchet, S. Gilfillan, M. Cella, B. Beutler, R. A. Flavell, M. S. Diamond, and M. Colonna. 2006. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 103:8459–8464.
   PubMed Web of Science ®Google Scholar
• Groskreutz, D. J., M. M. Monick, T. O. Yarovinsky, L. S. Powers, D. E. Quelle, S. M. Varga, D. C. Look, and G. W. Hunninghake. 2007. Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells. J. Immunol. 179:2741–2747.
   PubMed Web of Science ®Google Scholar
• Hayden, M. S., and S. Ghosh. 2008. Shared principles in NF-kappaB signaling. Cell 132:344–362.
   PubMed Web of Science ®Google Scholar
• Heil, F., H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer. 2004. Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303:1526–1529.
   PubMed Web of Science ®Google Scholar
• Hirata, Y., A. H. Broquet, L. Menchen, and M. F. Kagnoff. 2007. Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells. J. Immunol. 179:5425–5432.
   PubMedGoogle Scholar
• Hoh, J., S. Jin, T. Parrado, J. Edington, A. J. Levine, and J. Ott. 2002. The p53MH algorithm and its application in detecting p53-responsive genes. Proc. Natl. Acad. Sci. USA 99:8467–8472.
   PubMed Web of Science ®Google Scholar
• Jiang, Z., M. Zamanian-Daryoush, H. Nie, A. M. Silva, B. R. Williams, and X. Li. 2003. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J. Biol. Chem. 278:16713–16719.
   PubMedGoogle Scholar
• Joerger, A. C., and A. R. Fersht. 2008. Structural biology of the tumor suppressor p53. Annu. Rev. Biochem. 77:557–582.
   PubMed Web of Science ®Google Scholar
• Kato, H., O. Takeuchi, S. Sato, M. Yoneyama, M. Yamamoto, K. Matsui, S. Uematsu, A. Jung, T. Kawai, K. J. Ishii, O. Yamaguchi, K. Otsu, T. Tsujimura, C. S. Koh, C. Reis e Sousa, Y. Matsuura, T. Fujita, and S. Akira. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441:101–105.
   PubMed Web of Science ®Google Scholar
• Kawai, T., and S. Akira. 2006. Innate immune recognition of viral infection. Nat. Immunol. 7:131–137.
   PubMed Web of Science ®Google Scholar
• Krishnan, J., K. Selvarajoo, M. Tsuchiya, G. Lee, and S. Choi. 2007. Toll-like receptor signal transduction. Exp. Mol. Med. 39:421–438.
   PubMed Web of Science ®Google Scholar
• Lu, Z., K. A. Kim, M. A. Suico, T. Shuto, J. D. Li, and H. Kai. 2004. MEF up-regulates human beta-defensin 2 expression in epithelial cells. FEBS Lett. 561:117–121.
   PubMed Web of Science ®Google Scholar
• Marques, J. T., D. Rebouillat, C. V. Ramana, J. Murakami, J. E. Hill, A. Gudkov, R. H. Silverman, G. R. Stark, and B. R. G. Williams. 2005. Down-regulation of p53 by double-stranded RNA modulates the antiviral response. J. Virol. 79:11105–11114.
   PubMedGoogle Scholar
• Matsukura, S., F. Kokubu, M. Kurokawa, M. Kawaguchi, K. Ieki, H. Kuga, M. Odaka, S. Suzuki, S. Watanabe, T. Homma, H. Takeuchi, K. Nohtomi, and M. Adachi. 2007. Role of RIG-I, MDA-5, and PKR on the expression of inflammatory chemokines induced by synthetic dsRNA in airway epithelial cells. Int. Arch. Allergy Immunol. 143(Suppl. 1):80–83.
   PubMedGoogle Scholar
• Matsumoto, M., and T. Seya. 2008. TLR3: interferon induction by double-stranded RNA including poly(I:C). Adv. Drug Deliv. Rev. 60:805–812.
   PubMed Web of Science ®Google Scholar
• Meylan, E., J. Tschopp, and M. Karin. 2006. Intracellular pattern recognition receptors in the host response. Nature 442:39–44.
   PubMed Web of Science ®Google Scholar
• Moiseeva, O., F. A. Mallette, U. K. Mukhopadhyay, A. Moores, and G. Ferbeyre. 2006. DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation. Mol. Biol. Cell 17:1583–1592.
   PubMedGoogle Scholar
• Munoz-Fontela, C., M. A. Garcia, I. Garcia-Cao, M. Collado, J. Arroyo, M. Esteban, M. Serrano, and C. Rivas. 2005. Resistance to viral infection of super p53 mice. Oncogene 24:3059–3062.
   PubMedGoogle Scholar
• Oster, B., E. Kofod-Olsen, B. Bundgaard, and P. Hollsberg. 2008. Restriction of human herpesvirus 6B replication by p53. J. Gen. Virol. 89:1106–1113.
   PubMed Web of Science ®Google Scholar
• Riley, T., E. Sontag, P. Chen, and A. Levine. 2008. Transcriptional control of human p53-regulated genes. Nat. Rev. Mol. Cell Biol. 9:402–412.
   PubMed Web of Science ®Google Scholar
• Sato, K., T. Ishikawa, A. Okumura, T. Yamauchi, S. Sato, M. Ayada, E. Matsumoto, N. Hotta, T. Oohashi, Y. Fukuzawa, and S. Kakumu. 2007. Expression of Toll-like receptors in chronic hepatitis C virus infection. J. Gastroenterol. Hepatol. 22:1627–1632.
   PubMed Web of Science ®Google Scholar
• Seki, Y., M. A. Suico, A. Uto, A. Hisatsune, T. Shuto, Y. Isohama, and H. Kai. 2002. The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome. Cancer Res. 62:6579–6586.
   PubMed Web of Science ®Google Scholar
• Severa, M., and K. A. Fitzgerald. 2007. TLR-mediated activation of type I IFN during antiviral immune responses: fighting the battle to win the war. Curr. Top. Microbiol. Immunol. 316:167–192.
   PubMed Web of Science ®Google Scholar
• Shuto, T., T. Furuta, M. Oba, H. Xu, J. D. Li, J. Cheung, D. C. Gruenert, A. Uehara, M. A. Suico, T. Okiyoneda, and H. Kai. 2006. Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells. FASEB J. 20:782–784.
   PubMed Web of Science ®Google Scholar
• Suico, M. A., H. Yoshida, Y. Seki, T. Uchikawa, Z. Lu, T. Shuto, K. Matsuzaki, M. Nakao, J. D. Li, and H. Kai. 2004. Myeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia protein. J. Biol. Chem. 279:19091–19098.
   PubMedGoogle Scholar
• Takaoka, A., S. Hayakawa, H. Yanai, D. Stoiber, H. Negishi, H. Kikuchi, S. Sasaki, K. Imai, T. Shibue, K. Honda, and T. Taniguchi. 2003. Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 424:516–523.
   PubMed Web of Science ®Google Scholar
• Tamura, T., N. Aoyama, H. Saya, H. Haga, S. Futami, M. Miyamoto, T. Koh, T. Ariyasu, M. Tachi, M. Kasuga, et al. 1995. Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells. Oncogene 11:1939–1946.
   PubMed Web of Science ®Google Scholar
• Tanabe, M., M. Kurita-Taniguchi, K. Takeuchi, M. Takeda, M. Ayata, H. Ogura, M. Matsumoto, and T. Seya. 2003. Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains. Biochem. Biophys. Res. Commun. 311:39–48.
   PubMedGoogle Scholar
• Tsukada, T., Y. Tomooka, S. Takai, Y. Ueda, S. Nishikawa, T. Yagi, T. Tokunaga, N. Takeda, Y. Suda, S. Abe, I. Matsuo, Y. Ikawa, and S. Aizawa. 1993. Enhanced proliferative potential in culture of cells from p53-deficient mice. Oncogene 8:3313–3322.
   PubMed Web of Science ®Google Scholar
• Turpin, E., K. Luke, J. Jones, T. Tumpey, K. Konan, and S. Schultz-Cherry. 2005. Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication. J. Virol. 79:8802–8811.
   PubMed Web of Science ®Google Scholar
• Vercammen, E., J. Staal, and R. Beyaert. 2008. Sensing of viral infection and activation of innate immunity by Toll-like receptor 3. Clin. Microbiol. Rev. 21:13–25.
   PubMed Web of Science ®Google Scholar
• Vousden, K. H., and D. P. Lane. 2007. p53 in health and disease. Nat. Rev. Mol. Cell Biol. 8:275–283.
   PubMed Web of Science ®Google Scholar
• Yugawa, T., K. Handa, M. Narisawa-Saito, S.-I. Ohno, M. Fujita, and T. Kiyono. 2007. Regulation of Notch1 gene expression by p53 in epithelial cells. Mol. Cell. Biol. 27:3732–3742.
   PubMedGoogle Scholar