Myeloid Translocation Gene Family Members Associate with T-Cell Factors (TCFs) and Influence TCF-Dependent Transcription

REFERENCES

• Amann, J. M., B. J. Chyla, T. C. Ellis, A. Martinez, A. C. Moore, J. L. Franklin, L. McGhee, S. Meyers, J. E. Ohm, K. S. Luce, A. J. Ouelette, M. K. Washington, M. A. Thompson, D. King, S. Gautam, R. J. Coffey, R. H. Whitehead, and S. W. Hiebert. 2005. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Mol. Cell. Biol. 25:9576–9585.
   PubMed Web of Science ®Google Scholar
• Amann, J. M., J. Nip, D. K. Strom, B. Lutterbach, H. Harada, N. Lenny, J. R. Downing, S. Meyers, and S. W. Hiebert. 2001. ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. Mol. Cell. Biol. 21:6470–6483.
   PubMed Web of Science ®Google Scholar
• Batlle, E., J. T. Henderson, H. Beghtel, M. M. van den Born, E. Sancho, G. Huls, J. Meeldijk, J. Robertson, M. van de Wetering, T. Pawson, and H. Clevers. 2002. Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111:251–263.
   PubMed Web of Science ®Google Scholar
• Behrens, J., J. P. von Kries, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, and W. Birchmeier. 1996. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382:638–642.
   PubMed Web of Science ®Google Scholar
• Calabi, F., R. Pannell, and G. Pavloska. 2001. Gene targeting reveals a crucial role for MTG8 in the gut. Mol. Cell. Biol. 21:5658–5666.
   PubMed Web of Science ®Google Scholar
• Cao, Y., H. Zhao, and H. Grunz. 2002. XETOR regulates the size of the proneural domain during primary neurogenesis in Xenopus laevis. Mech. Dev. 119:35–44.
   PubMedGoogle Scholar
• Chamorro, M. N., D. R. Schwartz, A. Vonica, A. H. Brivanlou, K. R. Cho, and H. E. Varmus. 2005. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. EMBO J. 24:73–84.
   PubMed Web of Science ®Google Scholar
• Chevallier, N., C. M. Corcoran, C. Lennon, E. Hyjek, A. Chadburn, V. J. Bardwell, J. D. Licht, and A. Melnick. 2004. ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein. Blood 103:1454–1463.
   PubMed Web of Science ®Google Scholar
• Daniels, D. L., and W. I. Weis. 2005. Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat. Struct. Mol. Biol. 12:364–371.
   PubMed Web of Science ®Google Scholar
• Davis, J. N., L. McGhee, and S. Meyers. 2003. The ETO (MTG8) gene family. Gene 303:1–10.
   PubMed Web of Science ®Google Scholar
• Funayama, N., F. Fagotto, P. McCrea, and B. M. Gumbiner. 1995. Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling. J. Cell Biol. 128:959–968.
   PubMed Web of Science ®Google Scholar
• Gelmetti, V., J. Zhang, M. Fanelli, S. Minucci, P. G. Pelicci, and M. A. Lazar. 1998. Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO. Mol. Cell. Biol. 18:7185–7191.
   PubMed Web of Science ®Google Scholar
• Goardon, N., J. A. Lambert, P. Rodriguez, P. Nissaire, S. Herblot, P. Thibault, D. Dumenil, J. Strouboulis, P. H. Romeo, and T. Hoang. 2006. ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. EMBO J. 25:357–366.
   PubMed Web of Science ®Google Scholar
• Gradl, D., A. Konig, and D. Wedlich. 2002. Functional diversity of Xenopus lymphoid enhancer factor/T-cell factor transcription factors relies on combinations of activating and repressing elements. J. Biol. Chem. 277:14159–14171.
   PubMedGoogle Scholar
• Gradl, D., M. Kuhl, and D. Wedlich. 1999. Keeping a close eye on Wnt-1/wg signaling in Xenopus. Mech. Dev. 86:3–15.
   PubMedGoogle Scholar
• Harada, N., Y. Tamai, T. Ishikawa, B. Sauer, K. Takaku, M. Oshima, and M. M. Taketo. 1999. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 18:5931–5942.
   PubMed Web of Science ®Google Scholar
• He, T. C., A. B. Sparks, C. Rago, H. Hermeking, L. Zawel, L. T. da Costa, P. J. Morin, B. Vogelstein, and K. W. Kinzler. 1998. Identification of c-MYC as a target of the APC pathway. Science 281:1509–1512.
   PubMed Web of Science ®Google Scholar
• He, X., J. P. Saint-Jeannet, J. R. Woodgett, H. E. Varmus, and I. B. Dawid. 1995. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374:617–622.
   PubMedGoogle Scholar
• Huber, O., R. Korn, J. McLaughlin, M. Ohsugi, B. G. Herrmann, and R. Kemler. 1996. Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59:3–10.
   PubMed Web of Science ®Google Scholar
• Ibañez, V., A. Sharma, S. Buonamici, A. Verma, S. Kalakonda, J. Wang, S. Kadkol, and Y. Saunthararajah. 2004. AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation. Cancer Res. 64:4547–4554.
   PubMed Web of Science ®Google Scholar
• Jensen, J., E. E. Pedersen, P. Galante, J. Hald, R. S. Heller, M. Ishibashi, R. Kageyama, F. Guillemot, P. Serup, and O. D. Madsen. 2000. Control of endodermal endocrine development by Hes-1. Nat. Genet. 24:36–44.
   PubMed Web of Science ®Google Scholar
• Kitabayashi, I., K. Ida, F. Morohoshi, A. Yokoyama, N. Mitsuhashi, K. Shimizu, N. Nomura, Y. Hayashi, and M. Ohki. 1998. The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1. Mol. Cell. Biol. 18:846–858.
   PubMedGoogle Scholar
• Kochetkova, M., O. L. McKenzie, A. J. Bais, J. M. Martin, G. A. Secker, R. Seshadri, J. A. Powell, S. J. Hinze, A. E. Gardner, H. E. Spendlove, N. J. O'Callaghan, A. M. Cleton-Jansen, C. Cornelisse, S. A. Whitmore, J. Crawford, G. Kremmidiotis, G. R. Sutherland, and D. F. Callen. 2002. CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3. Cancer Res. 62:4599–4604.
   PubMed Web of Science ®Google Scholar
• Korinek, V., N. Barker, P. Moerer, E. van Donselaar, G. Huls, P. J. Peters, and H. Clevers. 1998. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19:379–383.
   PubMed Web of Science ®Google Scholar
• Koyano-Nakagawa, N., and C. Kintner. 2005. The expression and function of MTG/ETO family proteins during neurogenesis. Dev. Biol. 278:22–34.
   PubMedGoogle Scholar
• Linggi, B., C. Müller-Tidow, L. van de Locht, M. Hu, J. Nip, H. Serve, W. E. Berdel, B. van der Reijden, D. E. Quelle, J. D. Rowley, J. Cleveland, J. H. Jansen, P. P. Pandolfi, and S. W. Hiebert. 2002. The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14ARF tumor suppressor in acute myeloid leukemia. Nat. Med. 8:743–750.
   PubMed Web of Science ®Google Scholar
• Linggi, B. E., S. J. Brandt, Z. W. Sun, and S. W. Hiebert. 2005. Translating the histone code into leukemia. J. Cell. Biochem. 96:938–950.
   PubMed Web of Science ®Google Scholar
• Longo, K. A., J. A. Kennell, M. J. Ochocinska, S. E. Ross, W. S. Wright, and O. A. MacDougald. 2002. Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. J. Biol. Chem. 277:38239–38244.
   PubMed Web of Science ®Google Scholar
• Löwenberg, B., J. R. Downing, and A. Burnett. 1999. Acute myeloid leukemia. N. Engl. J. Med. 341:1051-1062. (Erratum, 341:1484.)
   PubMed Web of Science ®Google Scholar
• Lutterbach, B., J. J. Westendorf, B. Linggi, A. Patten, M. Moniwa, J. R. Davie, K. D. Huynh, V. J. Bardwell, R. M. Lavinsky, M. G. Rosenfeld, C. Glass, E. Seto, and S. W. Hiebert. 1998. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol. Cell. Biol. 18:7176–7184.
   PubMed Web of Science ®Google Scholar
• Mann, B., M. Gelos, A. Siedow, M. L. Hanski, A. Gratchev, M. Ilyas, W. F. Bodmer, M. P. Moyer, E. O. Riecken, H. J. Buhr, and C. Hanski. 1999. Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc. Natl. Acad. Sci. USA 96:1603–1608.
   PubMed Web of Science ®Google Scholar
• Martinez, J. A., C. S. Williams, J. M. Amann, T. C. Ellis, I. Moreno-Miralles, M. K. Washington, P. Gregoli, and S. W. Hiebert. 2006. Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology 131:579–588.
   PubMedGoogle Scholar
• McGhee, L., J. Bryan, L. Elliott, H. L. Grimes, A. Kazanjian, J. N. Davis, and S. Meyers. 2003. Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism. J. Cell. Biochem. 89:1005–1018.
   PubMed Web of Science ®Google Scholar
• Melnick, A., G. W. Carlile, M. J. McConnell, A. Polinger, S. W. Hiebert, and J. D. Licht. 2000. AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood 96:3939–3947.
   PubMed Web of Science ®Google Scholar
• Melnick, A. M., J. J. Westendorf, A. Polinger, G. W. Carlile, S. Arai, H. J. Ball, B. Lutterbach, S. W. Hiebert, and J. D. Licht. 2000. The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein. Mol. Cell. Biol. 20:2075–2086.
   PubMed Web of Science ®Google Scholar
• Molenaar, M., J. Roose, J. Peterson, S. Venanzi, H. Clevers, and O. Destree. 1998. Differential expression of the HMG box transcription factors XTcf-3 and XLef-1 during early Xenopus development. Mech. Dev. 75:151–154.
   PubMedGoogle Scholar
• Müller-Tidow, C., B. Steffen, T. Cauvet, L. Tickenbrock, P. Ji, S. Diederichs, B. Sargin, G. Kohler, M. Stelljes, E. Puccetti, M. Ruthardt, S. DeVos, S. W. Hiebert, H. P. Koeffler, W. E. Berdel, and H. Serve. 2004. Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Mol. Cell. Biol. 24:2890–2904.
   PubMed Web of Science ®Google Scholar
• Nelson, W. J., and R. Nusse. 2004. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303:1483–1487.
   PubMed Web of Science ®Google Scholar
• Nieuwkoop, P. D., and J. Faber. 1967. Normal table of Xenopus laevis (Daudin). North-Holland Publishing Company, Amsterdam, The Netherlands.
   Google Scholar
• Peng, H. B. 1991. Xenopus laevis: practical uses in cell and molecular biology. Solutions and protocols. Methods Cell Biol. 36:657–662.
   PubMed Web of Science ®Google Scholar
• Pinto, D., and H. Clevers. 2005. Wnt control of stem cells and differentiation in the intestinal epithelium. Exp. Cell Res. 306:357–363.
   PubMed Web of Science ®Google Scholar
• Polakis, P. 2000. Wnt signaling and cancer. Genes Dev. 14:1837–1851.
   PubMed Web of Science ®Google Scholar
• Radtke, F., H. Clevers, and O. Riccio. 2006. From gut homeostasis to cancer. Curr. Mol. Med. 6:275–289.
   PubMed Web of Science ®Google Scholar
• Rockman, S. P., S. A. Currie, M. Ciavarella, E. Vincan, C. Dow, R. J. Thomas, and W. A. Phillips. 2001. Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma. J. Biol. Chem. 276:45113–45119.
   PubMedGoogle Scholar
• Rual, J. F., K. Venkatesan, T. Hao, T. Hirozane-Kishikawa, A. Dricot, N. Li, G. F. Berriz, F. D. Gibbons, M. Dreze, N. Ayivi-Guedehoussou, N. Klitgord, C. Simon, M. Boxem, S. Milstein, J. Rosenberg, D. S. Goldberg, L. V. Zhang, S. L. Wong, G. Franklin, S. Li, J. S. Albala, J. Lim, C. Fraughton, E. Llamosas, S. Cevik, C. Bex, P. Lamesch, R. S. Sikorski, J. Vandenhaute, H. Y. Zoghbi, A. Smolyar, S. Bosak, R. Sequerra, L. Doucette-Stamm, M. E. Cusick, D. E. Hill, F. P. Roth, and M. Vidal. 2005. Towards a proteome-scale map of the human protein-protein interaction network. Nature 437:1173–1178.
   PubMed Web of Science ®Google Scholar
• Schuh, A. H., A. J. Tipping, A. J. Clark, I. Hamlett, B. Guyot, F. J. Iborra, P. Rodriguez, J. Strouboulis, T. Enver, P. Vyas, and C. Porcher. 2005. ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis. Mol. Cell. Biol. 25:10235–10250.
   PubMed Web of Science ®Google Scholar
• Shroyer, N. F., D. Wallis, K. J. Venken, H. J. Bellen, and H. Y. Zoghbi. 2005. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 19:2412–2417.
   PubMed Web of Science ®Google Scholar
• Shtutman, M., J. Zhurinsky, I. Simcha, C. Albanese, M. D'Amico, R. Pestell, and A. Ben-Ze'ev. 1999. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. USA 96:5522–5527.
   PubMed Web of Science ®Google Scholar
• Sjöblom, T., S. Jones, L. D. Wood, D. W. Parsons, J. Lin, T. D. Barber, D. Mandelker, R. J. Leary, J. Ptak, N. Silliman, S. Szabo, P. Buckhaults, C. Farrell, P. Meeh, S. D. Markowitz, J. Willis, D. Dawson, J. K. Willson, A. F. Gazdar, J. Hartigan, L. Wu, C. Liu, G. Parmigiani, B. H. Park, K. E. Bachman, N. Papadopoulos, B. Vogelstein, K. W. Kinzler, and V. E. Velculescu. 2006. The consensus coding sequences of human breast and colorectal cancers. Science 314:268–274.
   PubMed Web of Science ®Google Scholar
• Sokol, S., J. L. Christian, R. T. Moon, and D. A. Melton. 1991. Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell 67:741–752.
   PubMedGoogle Scholar
• Tetsu, O., and F. McCormick. 1999. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398:422–426.
   PubMed Web of Science ®Google Scholar
• van Es, J. H., P. Jay, A. Gregorieff, M. E. van Gijn, S. Jonkheer, P. Hatzis, A. Thiele, M. van den Born, H. Begthel, T. Brabletz, M. M. Taketo, and H. Clevers. 2005. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat. Cell Biol. 7:381–386.
   PubMed Web of Science ®Google Scholar
• van Noort, M., and H. Clevers. 2002. TCF transcription factors, mediators of Wnt-signaling in development and cancer. Dev. Biol. 244:1–8.
   PubMed Web of Science ®Google Scholar
• Wang, J., T. Hoshino, R. L. Redner, S. Kajigaya, and J. M. Liu. 1998. ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex. Proc. Natl. Acad. Sci. USA 95:10860–10865.
   PubMed Web of Science ®Google Scholar
• Willert, J., M. Epping, J. R. Pollack, P. O. Brown, and R. Nusse. 2002. A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev. Biol. 2:8.
   PubMedGoogle Scholar
• Wong, M. H., B. Rubinfeld, and J. I. Gordon. 1998. Effects of forced expression of an NH2-terminal truncated beta-catenin on mouse intestinal epithelial homeostasis. J. Cell Biol. 141:765–777.
   PubMed Web of Science ®Google Scholar
• Wood, J. D., F. C. Nucifora, Jr., K. Duan, C. Zhang, J. Wang, Y. Kim, G. Schilling, N. Sacchi, J. M. Liu, and C. A. Ross. 2000. Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription. J. Cell Biol. 150:939–948.
   PubMedGoogle Scholar
• Yang, Q., N. A. Bermingham, M. J. Finegold, and H. Y. Zoghbi. 2001. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294:2155–2158.
   PubMed Web of Science ®Google Scholar
• Zhang, J., M. Kalkum, S. Yamamura, B. T. Chait, and R. G. Roeder. 2004. E protein silencing by the leukemogenic AML1-ETO fusion protein. Science 305:1286–1289.
   PubMed Web of Science ®Google Scholar