13
Views
68
CrossRef citations to date
0
Altmetric
Article

Role of WISP-2/CCN5 in the Maintenance of a Differentiated and Noninvasive Phenotype in Human Breast Cancer Cells

, , , , , , , , & show all
Pages 1114-1123 | Received 25 Jul 2007, Accepted 16 Nov 2007, Published online: 27 Mar 2023

REFERENCES

  • Albertson, D. G., C. Collins, F. McCormick, and J. W. Gray. 2003. Chromosome aberrations in solid tumors. Nat. Genet. 34:369–376.
  • Al-Kuraya, K., P. Schraml, J. Torhorst, C. Tapia, B. Zaharieva, H. Novotny, H. Spichtin, R. Maurer, M. Mirlacher, O. Kochli, M. Zuber, H. Dieterich, F. Mross, K. Wilber, R. Simon, and G. Sauter. 2004. Prognostic relevance of gene amplifications and coamplifications in breast cancer. Cancer Res. 64:8534–8540.
  • Allinen, M., R. Beroukhim, L. Cai, C. Brennan, J. Lahti-Domenici, H. Huang, D. Porter, M. Hu, L. Chin, A. Richardson, S. Schnitt, W. R. Sellers, and K. Polyak. 2004. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 6:17–32.
  • Baj, G., A. Arnulfo, S. Deaglio, E. Tibaldi, N. Surico, and F. Malavasi. 1999. All-trans retinoic acid inhibits the growth of breast cancer cells by up-regulating ICAM-1 expression. J. Biol. Regul. Homeost. Agents 13:115–122.
  • Balmain, A., J. Gray, and B. Ponder. 2003. The genetics and genomics of cancer. Nat. Genet. 33(Suppl.):238–244.
  • Banerjee, S., N. Saxena, K. Sengupta, O. Tawfik, M. S. Mayo, and S. K. Banerjee. 2003. WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation. Neoplasia 5:63–73.
  • Banerjee, S., K. Sengupta, N. K. Saxena, K. Dhar, and S. K. Banerjee. 2005. Epidermal growth factor induces WISP-2/CCN5 expression in estrogen receptor-alpha-positive breast tumor cells through multiple molecular cross-talks. Mol. Cancer Res. 3:151–162.
  • Batlle, E., E. Sancho, C. Franci, D. Dominguez, M. Monfar, J. Baulida, and A. Garcia De Herreros. 2000. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2:84–89.
  • Bieche, I., B. Parfait, V. Le Doussal, M. Olivi, M. C. Rio, R. Lidereau, and M. Vidaud. 2001. Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy. Cancer Res. 61:1652–1658.
  • Bloom, H. J., and W. W. Richardson. 1957. Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br. J. Cancer 11:359–377.
  • Brigstock, D. R. 2003. The CCN family: a new stimulus package. J. Endocrinol. 178:169–175.
  • Brigstock, D. R. 1999. The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family. Endocr. Rev. 20:189–206.
  • Brigstock, D. R., R. Goldschmeding, K. I. Katsube, S. C. Lam, L. F. Lau, K. Lyons, C. Naus, B. Perbal, B. Riser, M. Takigawa, and H. Yeger. 2003. Proposal for a unified CCN nomenclature. Mol. Pathol. 56:127–128.
  • Cano, A., M. A. Perez-Moreno, I. Rodrigo, A. Locascio, M. J. Blanco, M. G. del Barrio, F. Portillo, and M. A. Nieto. 2000. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2:76–83.
  • Dangles, V., V. Lazar, P. Validire, S. Richon, M. Wertheimer, V. Laville, J. L. Janneau, M. Barrois, C. Bovin, T. Poynard, G. Vallancien, and D. Bellet. 2002. Gene expression profiles of bladder cancers: evidence for a striking effect of in vitro cell models on gene patterns. Br. J. Cancer 86:1283–1289.
  • De Craene, B., B. Gilbert, C. Stove, E. Bruyneel, F. van Roy, and G. Berx. 2005. The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res. 65:6237–6244.
  • Dhar, G., S. Mehta, S. Banerjee, A. Gardner, B. M. McCarty, S. C. Mathur, D. R. Campbell, S. Kambhampati, and S. K. Banerjee. 2007. Loss of WISP-2/CCN5 signaling in human pancreatic cancer: a potential mechanism for epithelial-mesenchymal-transition. Cancer Lett. 254:63–70.
  • Easton, D. F. 1999. How many more breast cancer predisposition genes are there? Breast Cancer Res. 1:14–17.
  • Fritah, A., G. Redeuilh, and M. Sabbah. 2006. Molecular cloning and characterization of the human WISP-2/CCN5 gene promoter reveal its upregulation by oestrogens. J. Endocrinol. 191:613–624.
  • Fritah, A., C. Saucier, J. Mester, G. Redeuilh, and M. Sabbah. 2005. p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha. Mol. Cell. Biol. 25:2419–2430.
  • Fujita, N., D. L. Jaye, M. Kajita, C. Geigerman, C. S. Moreno, and P. A. Wade. 2003. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell 113:207–219.
  • Gery, S., S. Tanosaki, S. Bose, N. Bose, J. Vadgama, and H. P. Koeffler. 2005. Down-regulation and growth inhibitory role of C/EBPalpha in breast cancer. Clin. Cancer Res. 11:3184–3190.
  • Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell 100:57–70.
  • Hyder, S. M., C. Chiappetta, L. Murthy, and G. M. Stancel. 1997. Selective inhibition of estrogen-regulated gene expression in vivo by the pure antiestrogen ICI 182,780. Cancer Res. 57:2547–2549.
  • Inadera, H. 2003. Estrogen-induced genes, WISP-2 and pS2, respond divergently to protein kinase pathway. Biochem. Biophys. Res. Commun. 309:272–278.
  • Itahana, Y., J. Singh, T. Sumida, J. P. Coppe, S. Parrinello, J. L. Bennington, and P. Y. Desprez. 2003. Role of Id-2 in the maintenance of a differentiated and noninvasive phenotype in breast cancer cells. Cancer Res. 63:7098–7105.
  • Kowanetz, M., U. Valcourt, R. Bergstrom, C. H. Heldin, and A. Moustakas. 2004. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol. Cell. Biol. 24:4241–4254.
  • Lake, A. C., A. Bialik, K. Walsh, and J. J. Castellot, Jr. 2003. CCN5 is a growth arrest-specific gene that regulates smooth muscle cell proliferation and motility. Am. J. Pathol. 162:219–231.
  • Lapteva, N., A. G. Yang, D. E. Sanders, R. W. Strube, and S. Y. Chen. 2005. CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo. Cancer Gene Ther. 12:84–89.
  • Leask, A., and D. J. Abraham. 2006. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J. Cell Sci. 119:4803–4810.
  • Malet, C., A. Gompel, H. Yaneva, H. Cren, N. Fidji, I. Mowszowicz, F. Kuttenn, and P. Mauvais-Jarvis. 1991. Estradiol and progesterone receptors in cultured normal human breast epithelial cells and fibroblasts: immunocytochemical studies. J. Clin. Endocrinol. Metab. 73:8–17.
  • Mason, H. R., A. C. Lake, J. E. Wubben, R. A. Nowak, and J. J. Castellot, Jr. 2004. The growth arrest-specific gene CCN5 is deficient in human leiomyomas and inhibits the proliferation and motility of cultured human uterine smooth muscle cells. Mol. Hum. Reprod. 10:181–187.
  • Muller, A., B. Homey, H. Soto, N. Ge, D. Catron, M. E. Buchanan, T. McClanahan, E. Murphy, W. Yuan, S. N. Wagner, J. L. Barrera, A. Mohar, E. Verastegui, and A. Zlotnik. 2001. Involvement of chemokine receptors in breast cancer metastasis. Nature 410:50–56.
  • Parrinello, S., C. Q. Lin, K. Murata, Y. Itahana, J. Singh, A. Krtolica, J. Campisi, and P. Y. Desprez. 2001. Id-1, ITF-2, and Id-2 comprise a network of helix-loop-helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis. J. Biol. Chem. 276:39213–39219.
  • Pennica, D., T. A. Swanson, J. W. Welsh, M. A. Roy, D. A. Lawrence, J. Lee, J. Brush, L. A. Taneyhill, B. Deuel, M. Lew, C. Watanabe, R. L. Cohen, M. F. Melhem, G. G. Finley, P. Quirke, A. D. Goddard, K. J. Hillan, A. L. Gurney, D. Botstein, and A. J. Levine. 1998. WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc. Natl. Acad. Sci. USA 95:14717–14722.
  • Planque, N., and B. Perbal. 2003. A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis. Cancer Cell Int. 3:15.
  • Rachfal, A. W., and D. R. Brigstock. 2005. Structural and functional properties of CCN proteins. Vitam. Horm. 70:69–103.
  • Redeuilh, G., A. Attia, J. Mester, and M. Sabbah. 2002. Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases. Oncogene 21:5773–5782.
  • Saxena, N., S. Banerjee, K. Sengupta, M. N. Zoubine, and S. K. Banerjee. 2001. Differential expression of WISP-1 and WISP-2 genes in normal and transformed human breast cell lines. Mol. Cell. Biochem. 228:99–104.
  • Schwalbe, M., J. Sanger, R. Eggers, A. Naumann, A. Schmidt, K. Hoffken, and J. H. Clement. 2003. Differential expression and regulation of bone morphogenetic protein 7 in breast cancer. Int. J. Oncol. 23:89–95.
  • Sengupta, K., S. Banerjee, K. Dhar, N. K. Saxena, S. Mehta, D. R. Campbell, and S. K. Banerjee. 2006. WISP-2/CCN5 is involved as a novel signaling intermediate in phorbol ester-protein kinase Calpha-mediated breast tumor cell proliferation. Biochemistry 45:10698–10709.
  • Shipitsin, M., L. L. Campbell, P. Argani, S. Weremowicz, N. Bloushtain-Qimron, J. Yao, T. Nikolskaya, T. Serebryiskaya, R. Beroukhim, M. Hu, M. K. Halushka, S. Sukumar, L. M. Parker, K. S. Anderson, L. N. Harris, J. E. Garber, A. L. Richardson, S. J. Schnitt, Y. Nikolsky, R. S. Gelman, and K. Polyak. 2007. Molecular definition of breast tumor heterogeneity. Cancer Cell 11:259–273.
  • Thiery, J. P. 2002. Epithelial-mesenchymal transitions in tumour progression. Nat Rev. Cancer 2:442–454.
  • Thiery, J. P., and J. P. Sleeman. 2006. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7:131–142.
  • Visvader, J. E., and G. J. Lindeman. 2003. Transcriptional regulators in mammary gland development and cancer. Int. J. Biochem. Cell. Biol. 35:1034–1051.
  • Welsh, J. B., L. M. Sapinoso, A. I. Su, S. G. Kern, J. Wang-Rodriguez, C. A. Moskaluk, H. F. Frierson, Jr., and G. M. Hampton. 2001. Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res. 61:5974–5978.
  • Zhang, R., L. Averboukh, W. Zhu, H. Zhang, H. Jo, P. J. Dempsey, R. J. Coffey, A. B. Pardee, and P. Liang. 1998. Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation. Mol. Cell. Biol. 18:6131–6141.
  • Zoubine, M. N., S. Banerjee, N. K. Saxena, D. R. Campbell, and S. K. Banerjee. 2001. WISP-2: a serum-inducible gene differentially expressed in human normal breast epithelial cells and in MCF-7 breast tumor cells. Biochem. Biophys. Res. Commun. 282:421–425.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.