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Article

Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation

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Pages 3056-3064 | Received 20 Jul 2006, Accepted 22 Jan 2007, Published online: 27 Mar 2023

REFERENCES

  • Ballerini, P., A. Blaise, T. Mercher, B. Pellegrino, C. Perot, J. van den Akker, E. Gatbois, M. Adam, L. Douay, R. Berger, O. Bernard, and J. Landman-Parker. 2003. A novel real-time RT-PCR assay for quantification of OTT-MAL fusion transcript reliable for diagnosis of t(1;22) and minimal residual disease (MRD) detection. Leukemia 17:1193–1196.
  • Baruchel, A., M. T. Daniel, G. Schaison, and R. Berger. 1991. Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation. Cancer Genet. Cytogenet. 54:239–243.
  • Beatus, P., J. Lundkvist, C. Oberg, and U. Lendahl. 1999. The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. Development 126:3925–3935.
  • Bigas, A., D. I. Martin, and L. A. Milner. 1998. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell. Biol. 18:2324–2333.
  • Carroll, A., C. Civin, N. Schneider, G. Dahl, A. Pappo, P. Bowman, A. Emami, S. Gross, C. Alvarado, C. Phillips, et al. 1991. The t(1;22) (p13;q13) is nonrandom and restricted to infants with acute megakaryoblastic leukemia. Blood 78:748–752.
  • Charames, G. S., and B. Bapat. 2003. Genomic instability and cancer. Curr. Mol. Med. 3:589–596.
  • Chen, F., and I. Rebay. 2000. split ends, a new component of the Drosophila EGF receptor pathway, regulates development of midline glial cells. Curr. Biol. 10:943–946.
  • de Pooter, R. F., T. M. Schmitt, J. L. de la Pompa, Y. Fujiwara, S. H. Orkin, and J. C. Zuniga-Pflucker. 2006. Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors. J. Immunol. 176:5267–5275.
  • Du, K. L., M. Chen, J. Li, J. J. Lepore, P. Mericko, and M. S. Parmacek. 2004. Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells. J. Biol. Chem. 279:17578–17586.
  • Dumortier, A., R. Jeannet, P. Kirstetter, E. Kleinmann, M. Sellars, N. R. dos Santos, C. Thibault, J. Barths, J. Ghysdael, J. A. Punt, P. Kastner, and S. Chan. 2006. Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice. Mol. Cell. Biol. 26:209–220.
  • Duncan, A. W., F. M. Rattis, L. N. DiMascio, K. L. Congdon, G. Pazianos, C. Zhao, K. Yoon, J. M. Cook, K. Willert, N. Gaiano, and T. Reya. 2005. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nat. Immunol. 6:314–322.
  • Ellisen, L. W., J. Bird, D. C. West, A. L. Soreng, T. C. Reynolds, S. D. Smith, and J. Sklar. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649–661.
  • Evans, C. J., V. Hartenstein, and U. Banerjee. 2003. Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev. Cell 5:673–690.
  • Ge, Y., T. L. Jensen, M. L. Stout, R. M. Flatley, P. J. Grohar, Y. Ravindranath, L. H. Matherly, and J. W. Taub. 2004. The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines. Cancer Res. 64:728–735.
  • Hsiao, H. H., M. Y. Yang, Y. C. Liu, H. P. Hsiao, S. B. Tseng, M. C. Chao, T. C. Liu, and S. F. Lin. 2005. RBM15-MKL1 (OTT-MAL) fusion transcript in an adult acute myeloid leukemia patient. Am. J. Hematol. 79:43–45.
  • Hsieh, J. J., and S. D. Hayward. 1995. Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2. Science 268:560–563.
  • Ishiko, E., I. Matsumura, S. Ezoe, K. Gale, J. Ishiko, Y. Satoh, H. Tanaka, H. Shibayama, M. Mizuki, T. Era, T. Enver, and Y. Kanakura. 2005. Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. J. Biol. Chem. 280:4929–4939.
  • Jarriault, S., C. Brou, F. Logeat, E. H. Schroeter, R. Kopan, and A. Israel. 1995. Signalling downstream of activated mammalian Notch. Nature 377:355–358.
  • Jarriault, S., O. Le Bail, E. Hirsinger, O. Pourquie, F. Logeat, C. F. Strong, C. Brou, N. G. Seidah, and A. Israel. 1998. Delta-1 activation of notch-1 signaling results in HES-1 transactivation. Mol. Cell. Biol. 18:7423–7431.
  • Jemc, J., and I. Rebay. 2006. Characterization of the split ends-like gene spenito reveals functional antagonism between SPOC family members during Drosophila eye development. Genetics 173:279–286.
  • Kawaguchi, H., J. K. Hitzler, Z. Ma, and S. W. Morris. 2005. RBM15 and MKL1 mutational screening in megakaryoblastic leukemia cell lines and clinical samples. Leukemia 19:1492–1494.
  • Khanna-Gupta, A., T. Zibello, H. Sun, J. Lekstrom-Himes, and N. Berliner. 2001. C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut). Proc. Natl. Acad. Sci. USA 98:8000–8005.
  • Kovall, R. A., and W. A. Hendrickson. 2004. Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. EMBO J. 23:3441–3451.
  • Krause, D. S. 2002. Regulation of hematopoietic stem cell fate. Oncogene 21:3262–3269.
  • Kuang, B., S. C. Wu, Y. Shin, L. Luo, and P. Kolodziej. 2000. split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo. Development 127:1517–1529.
  • Kuroda, K., H. Han, S. Tani, K. Tanigaki, T. Tun, T. Furukawa, Y. Taniguchi, H. Kurooka, Y. Hamada, S. Toyokuni, and T. Honjo. 2003. Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity 18:301–312.
  • Kuwahara, K., T. Barrientos, G. C. Pipes, S. Li, and E. N. Olson. 2005. Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol. Cell. Biol. 25:3173–3181.
  • Leong, G. M., N. Subramaniam, L. L. Issa, J. B. Barry, T. Kino, P. H. Driggers, M. J. Hayman, J. A. Eisman, and E. M. Gardiner. 2004. Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300. Biochem. Biophys. Res. Commun. 315:1070–1076.
  • Liang, Y., J. Chang, S. J. Lynch, D. M. Lukac, and D. Ganem. 2002. The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. Genes Dev. 16:1977–1989.
  • Lion, T., O. A. Haas, J. Harbott, E. Bannier, J. Ritterbach, M. Jankovic, F. M. Fink, A. Stojimirovic, J. Herrmann, H. J. Riehm, et al. 1992. The translocation t(1;22)(p13;q13) is a nonrandom marker specifically associated with acute megakaryocytic leukemia in young children. Blood 79:3325–3330.
  • Ma, Z., S. W. Morris, V. Valentine, M. Li, J. A. Herbrick, X. Cui, D. Bouman, Y. Li, P. K. Mehta, D. Nizetic, Y. Kaneko, G. C. Chan, L. C. Chan, J. Squire, S. W. Scherer, and J. K. Hitzler. 2001. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat. Genet. 28:220–221.
  • Magalhaes, I. Q., A. Splendore, M. Emerenciano, A. Figueiredo, I. Ferrari, and M. S. Pombo-de-Oliveira. 2006. GATA1 mutations in acute leukemia in children with Down syndrome. Cancer Genet. Cytogenet 166:112–116.
  • Maillard, I., A. P. Weng, A. C. Carpenter, C. G. Rodriguez, H. Sai, L. Xu, D. Allman, J. C. Aster, and W. S. Pear. 2004. Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood 104:1696–1702.
  • Mercher, T., M. Busson-Le Coniat, F. N. Khac, P. Ballerini, M. Mauchauffe, H. Bui, B. Pellegrino, I. Radford, F. Valensi, F. Mugneret, N. Dastugue, O. A. Bernard, and R. Berger. 2002. Recurrence of OTT-MAL fusion in t(1;22) of infant AML-M7. Genes Chromosomes Cancer 33:22–28.
  • Mercher, T., M. B. Coniat, R. Monni, M. Mauchauffe, F. N. Khac, L. Gressin, F. Mugneret, T. Leblanc, N. Dastugue, R. Berger, and O. A. Bernard. 2001. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. Proc. Natl. Acad. Sci. USA. 98:5776–5779.
  • Milner, L. A., and A. Bigas. 1999. Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. Blood 93:2431–2448.
  • Milner, L. A., A. Bigas, R. Kopan, C. Brashem-Stein, I. D. Bernstein, and D. I. K. Martin. 1996. Inhibition of granuloctic differentiation by mNotch1. Proc. Natl. Acad. Sci. USA 93:13014–13019.
  • Oswald, F., U. Kostezka, K. Astrahantseff, S. Bourteele, K. Dillinger, U. Zechner, L. Ludwig, M. Wilda, H. Hameister, W. Knochel, S. Liptay, and R. M. Schmid. 2002. SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J. 21:5417–5426.
  • Pavlova, S., J. Mayer, H. Koukalova, and J. Smardova. 2003. High frequency of temperature-sensitive mutations of p53 tumor suppressor in acute myeloid leukemia revealed by functional assay in yeast. Int. J. Oncol. 23:121–131.
  • Pihan, G., and S. J. Doxsey. 2003. Mutations and aneuploidy: co-conspirators in cancer? Cancer Cell 4:89–94.
  • Radtke, F., A. Wilson, S. J. Mancini, and H. R. MacDonald. 2004. Notch regulation of lymphocyte development and function. Nat. Immunol. 5:247–253.
  • Schroeder, T., and U. Just. 2000. Notch signalling via RBP-J promotes myeloid differentiation. EMBO J. 19:2558–2568.
  • Schroeder, T., H. Kohlhof, N. Rieber, and U. Just. 2003. Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression. J. Immunol. 170:5538–5548.
  • Schroeter, E. H., J. A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393:382–386.
  • Shi, Y., M. Downes, W. Xie, H. Y. Kao, P. Ordentlich, C. C. Tsai, M. Hon, and R. M. Evans. 2001. Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes Dev. 15:1140–1151.
  • Shivdasani, R. A. 1997. Stem cell transcription factors. Hematol. Oncol. Clin. N. Am. 11:1199–1206.
  • Sierra, O. L., S. L. Cheng, A. P. Loewy, N. Charlton-Kachigian, and D. A. Towler. 2004. MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element. J. Biol. Chem. 279:32913–32923.
  • Stachura, D. L., S. T. Chou, and M. J. Weiss. 2006. Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. Blood 107:87–97.
  • Vas, V., L. Szilagyi, K. Paloczi, and F. Uher. 2004. Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay. J. Leukoc. Biol. 75:714–720.
  • Wechsler, J., M. Greene, M. A. McDevitt, J. Anastasi, J. E. Karp, M. M. Le Beau, and J. D. Crispino. 2002. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat. Genet. 32:148–152.
  • Zhou, S., M. Fujimuro, J. J. Hsieh, L. Chen, A. Miyamoto, G. Weinmaster, and S. D. Hayward. 2000. SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol. Cell. Biol. 20:2400–2410.

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