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Article

Adenine Nucleotide Translocator Cooperates with Core Cell Death Machinery To Promote Apoptosis in Caenorhabditis elegans

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Pages 3881-3893 | Received 27 Sep 2008, Accepted 28 Apr 2009, Published online: 21 Mar 2023

REFERENCES

  • Bauer, M. K., A. Schubert, O. Rocks, and S. Grimm. 1999. Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis. J. Cell Biol. 147:1493–1502.
  • Belzacq, A. S., H. L. Vieira, G. Kroemer, and C. Brenner. 2002. The adenine nucleotide translocator in apoptosis. Biochimie 84:167–176.
  • Belzacq, A. S., H. L. Vieira, F. Verrier, G. Vandecasteele, I. Cohen, M. C. Prevost, E. Larquet, F. Pariselli, P. X. Petit, A. Kahn, R. Rizzuto, C. Brenner, and G. Kroemer. 2003. Bcl-2 and Bax modulate adenine nucleotide translocase activity. Cancer Res. 63:541–546.
  • Bloss, T. A., E. S. Witze, and J. H. Rothman. 2003. Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans. Nature 424:1066–1071.
  • Brenner, S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71–94.
  • Chen, F., B. M. Hersh, B. Conradt, Z. Zhou, D. Riemer, Y. Gruenbaum, and H. R. Horvitz. 2000. Translocation of Caenorhabditis elegans CED-4 to nuclear membranes during programmed cell death. Science 287:1485–1489.
  • Chen, L., T. McCloskey, P. M. Joshi, and J. H. Rothman. 2008. ced-4 and proto-oncogene tfg-1 antagonistically regulate cell size and apoptosis in Caenorhabditis elegans. Curr. Biol. 18:1025–1033.
  • Conradt, B., and H. R. Horvitz. 1998. The Caenorhabditis elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93:519–529.
  • Cory, S., and J. M. Adams. 2002. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2:647–656.
  • Crompton, M., E. Barksby, N. Johnson, and M. Capano. 2002. Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie 84:143–152.
  • Dasgupta, N., A. M. Patel, B. A. Scott, and C. M. Crowder. 2007. Hypoxic preconditioning requires the apoptosis protein CED-4 in Caenorhabditis elegans. Curr. Biol. 17:1954–1959.
  • Delivani, P., C. Adrain, R. C. Taylor, P. J. Duriez, and S. J. Martin. 2006. Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Mol. Cell 21:761–773.
  • del Peso, L., V. M. Gonzalez, and G. Nunez. 1998. Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation. J. Biol. Chem. 273:33495–33500.
  • Dolce, V., P. Scarcia, D. Iacopetta, and F. Palmieri. 2005. A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution. FEBS Lett. 579:633–637.
  • Gumienny, T. L., E. Lambie, E. Hartwieg, H. R. Horvitz, and M. O. Hengartner. 1999. Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development 126:1011–1022.
  • Halestrap, A. P., G. P. McStay, and S. J. Clarke. 2002. The permeability transition pore complex: another view. Biochimie 84:153–166.
  • Horvitz, H. R. 2003. Nobel lecture: worms, life, and death. Biosci. Rep. 23:239–303.
  • Jagasia, R., P. Grote, B. Westermann, and B. Conradt. 2005. DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in Caenorhabditis elegans. Nature 433:754–760.
  • Kokoszka, J. E., K. G. Waymire, S. E. Levy, J. E. Sligh, J. Cai, D. P. Jones, G. R. MacGregor, and D. C. Wallace. 2004. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427:461–465.
  • Kroemer, G., L. Galluzzi, and C. Brenner. 2007. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87:99–163.
  • Le Bras, M., A. Borgne-Sanchez, Z. Touat, O. S. El Dein, A. Deniaud, E. Maillier, G. Lecellier, D. Rebouillat, C. Lemaire, G. Kroemer, E. Jacotot, and C. Brenner. 2006. Chemosensitization by knockdown of adenine nucleotide translocase-2. Cancer Res. 66:9143–9152.
  • Liu, H., T. J. Strauss, M. B. Potts, and S. Cameron. 2006. Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a Caenorhabditis elegans homolog of Pbx1. Development 133:641–650.
  • Marzo, I., C. Brenner, N. Zamzami, J. M. Jurgensmeier, S. A. Susin, H. L. Vieira, M. C. Prevost, Z. Xie, S. Matsuyama, J. C. Reed, and G. Kroemer. 1998. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281:2027–2031.
  • Mello, C., and A. Fire. 1995. DNA transformation. Methods Cell Biol. 48:451–482.
  • Mello, C. C., J. M. Kramer, D. Stinchcomb, and V. Ambros. 1991. Efficient gene transfer in Caenorhabditis elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10:3959–3970.
  • Parrish, J., L. Li, K. Klotz, D. Ledwich, X. Wang, and D. Xue. 2001. Mitochondrial endonuclease G is important for apoptosis in Caenorhabditis elegans. Nature 412:90–94.
  • Parrish, J., H. Metters, L. Chen, and D. Xue. 2000. Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors. Proc. Natl. Acad. Sci. USA 97:11916–11921.
  • Pebay-Peyroula, E., C. Dahout-Gonzalez, R. Kahn, V. Trezeguet, G. J. Lauquin, and G. Brandolin. 2003. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426:39–44.
  • Reddien, P. W., and H. R. Horvitz. 2004. The engulfment process of programmed cell death in Caenorhabditis elegans. Annu. Rev. Cell Dev. Biol. 412:98–202.
  • Savage, C., M. Hamelin, J. G. Culotti, A. Coulson, D. G. Albertson, and M. Chalfie. 1989. mec-7 is a β-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans. Genes Dev. 3:870–881.
  • Shaham, S., and H. R. Horvitz. 1996. Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes Dev. 10:578–591.
  • Stepien, G., A. Torroni, A. B. Chung, J. A. Hodge, and D. C. Wallace. 1992. Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation. J. Biol. Chem. 267:14592–14597.
  • Wang, X. 2001. The expanding role of mitochondria in apoptosis. Genes Dev. 15:2922–2933.
  • Wang, X., J. Wang, K. Gengyo-Ando, L. Gu, C. L. Sun, C. Yang, Y. Shi, T. Kobayashi, Y. Shi, S. Mitani, X. S. Xie, and D. Xue. 2007. Caenorhabditis elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1. Nat. Cell Biol. 9:541–549.
  • Wang, X., Y. C. Wu, V. A. Fadok, M. C. Lee, K. Gengyo-Ando, L. C. Cheng, D. Ledwich, P. K. Hsu, J. Y. Chen, B. K. Chou, P. Henson, S. Mitani, and D. Xue. 2003. Cell corpse engulfment mediated by Caenorhabditis elegans phosphatidylserine receptor through CED-5 and CED-12. Science 302:1563–1566.
  • Wang, X., C. Yang, J. Chai, Y. Shi, and D. Xue. 2002. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 298:1587–1592.
  • Wu, D., H. D. Wallen, and G. Nunez. 1997. Interaction and regulation of subcellular localization of CED-4 by CED-9. Science 275:1126–1129.
  • Xiao, H., D. Chen, Z. Fang, J. Xu, X. Sun, S. Song, J. Liu, and C. Yang. 2009. Lysosome biogenesis mediated by vps-18 affects apoptotic cell degradation in Caenorhabditis elegans. Mol. Biol. Cell 20:21–32.
  • Yan, N., J. Chai, E. S. Lee, L. Gu, Q. Liu, J. He, J. W. Wu, D. Kokel, H. Li, Q. Hao, D. Xue, and Y. Shi. 2005. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature 437:831–837.
  • Yan, N., L. Gu, D. Kokel, J. Chai, W. Li, A. Han, L. Chen, D. Xue, and Y. Shi. 2004. Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4. Mol. Cell 15:999–1006.
  • Yang, X., H. Y. Chang, and D. Baltimore. 1998. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science 281:1355–1357.
  • Yang, Z., W. Cheng, L. Hong, W. Chen, Y. Wang, S. Lin, J. Han, H. Zhou, and J. Gu. 2007. Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells. Mol. Biol. Cell 18:4681–4689.
  • Yu, X., S. Odera, C. H. Chuang, N. Lu, and Z. Zhou. 2006. Caenorhabditis elegans dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells. Dev. Cell 10:743–757.
  • Zamora, M., M. Granell, T. Mampel, and O. Vinas. 2004. Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. FEBS Lett. 563:155–160.
  • Zamzami, N., S. A. Susin, P. Marchetti, T. Hirsch, I. Gomez-Monterrey, M. Castedo, and G. Kroemer. 1996. Mitochondrial control of nuclear apoptosis. J. Exp. Med. 183:1533–1544.

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