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Article

Cotranscriptional Splicing Potentiates the mRNA Production from a Subset of Estradiol-Stimulated Genes

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Pages 5811-5824 | Received 17 Dec 2007, Accepted 07 Jul 2008, Published online: 27 Mar 2023

REFERENCES

  • Aiyar, S. E., J. L. Sun, A. L. Blair, C. A. Moskaluk, Y. Z. Lu, Q. N. Ye, Y. Yamaguchi, A. Mukherjee, D. M. Ren, H. Handa, and R. Li. 2004. Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes Dev. 18:2134–2146.
  • Auboeuf, D., A. Honig, S. M. Berget, and B. W. O'Malley. 2002. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science 298:416–419.
  • Barbier, J., M. Dutertre, D. Bittencourt, G. Sanchez, L. Gratadou, P. de la Grange, and D. Auboeuf. 2007. Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways. Mol. Cell. Biol. 27:7315–7333.
  • Batsche, E., M. Yaniv, and C. Muchardt. 2006. The human SWI/SNF subunit Brm is a regulator of alternative splicing. Nat. Struct. Mol. Biol. 13:22–29.
  • Beelman, C. A., and R. Parker. 1995. Degradation of mRNA in eukaryotes. Cell 81:179–183.
  • Bentley, D. 2002. The mRNA assembly line: transcription and processing machines in the same factory. Curr. Opin. Cell Biol. 14:336–342.
  • Bird, G., D. A. Zorio, and D. L. Bentley. 2004. RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3′-end formation. Mol. Cell. Biol. 24:8963–8969.
  • Brodsky, A. S., C. A. Meyer, I. A. Swinburne, G. Hall, B. J. Keenan, X. S. Liu, E. A. Fox, and P. A. Silver. 2005. Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biol. 6:R64.
  • Cascio, S., V. Bartella, C. Garofalo, A. Russo, A. Giordano, and E. Surmacz. 2007. Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J. Biol. Chem. 282:3498–3506.
  • Cheng, C., and P. A. Sharp. 2003. RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol. Cell. Biol. 23:1961–1967.
  • Custodio, N., M. Carmo-Fonseca, F. Geraghty, H. S. Pereira, F. Grosveld, and M. Antoniou. 1999. Inefficient processing impairs release of RNA from the site of transcription. EMBO J. 18:2855–2866.
  • Damgaard, C. K., S. Kahns, S. Lykke-Andersen, A. L. Nielsen, T. H. Jensen, and J. Kjems. 2008. A 5′ splice site enhances the recruitment of basal transcription initiation factors in vivo. Mol. Cell 29:271–278.
  • Das, R., K. Dufu, B. Romney, M. Feldt, M. Elenko, and R. Reed. 2006. Functional coupling of RNAP II transcription to spliceosome assembly. Genes Dev. 20:1100–1109.
  • Das, R., J. Yu, Z. Zhang, M. P. Gygi, A. R. Krainer, S. P. Gygi, and R. Reed. 2007. SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol. Cell 26:867–881.
  • Dubois, M. F., V. T. Nguyen, S. Bellier, and O. Bensaude. 1994. Inhibitors of transcription such as 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole and isoquinoline sulfonamide derivatives (H-8 and H-7) promote dephosphorylation of the carboxyl-terminal domain of RNA polymerase II largest subunit. J. Biol. Chem. 269:13331–13336.
  • Eeckhoute, J., J. S. Carroll, T. R. Geistlinger, M. I. Torres-Arzayus, and M. Brown. 2006. A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes Dev. 20:2513–2526.
  • Flaherty, S. M., P. Fortes, E. Izaurralde, I. W. Mattaj, and G. M. Gilmartin. 1997. Participation of the nuclear cap binding complex in pre-mRNA 3′ processing. Proc. Natl. Acad. Sci. USA 94:11893–11898.
  • Ghosh, S., and M. A. Garcia-Blanco. 2000. Coupled in vitro synthesis and splicing of RNA polymerase II transcripts. RNA 6:1325–1334.
  • Heldring, N., A. Pike, S. Andersson, J. Matthews, G. Cheng, J. Hartman, M. Tujague, A. Strom, E. Treuter, M. Warner, and J. A. Gustafsson. 2007. Estrogen receptors: how do they signal and what are their targets. Physiol. Rev. 87:905–931.
  • Hicks, M. J., C. R. Yang, M. V. Kotlajich, and K. J. Hertel. 2006. Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. PLoS Biol. 4:e147.
  • Ikeda, K., S. Ogawa, T. Tsukui, K. Horie-Inoue, Y. Ouchi, S. Kato, M. Muramatsu, and S. Inoue. 2004. Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription. Mol. Endocrinol. 18:1131–1143.
  • Kabrane-Lazizi, Y., X. J. Meng, R. H. Purcell, and S. U. Emerson. 1999. Evidence that the genomic RNA of hepatitis E virus is capped. J. Virol. 73:8848–8850.
  • Kaneko, S., and J. L. Manley. 2005. The mammalian RNA polymerase II C-terminal domain interacts with RNA to suppress transcription-coupled 3′ end formation. Mol. Cell 20:91–103.
  • Kaneko, S., O. Rozenblatt-Rosen, M. Meyerson, and J. L. Manley. 2007. The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3′ processing and transcription termination. Genes Dev. 21:1779–1789.
  • Kessler, O., Y. Jiang, and L. A. Chasin. 1993. Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA. Mol. Cell. Biol. 13:6211–6222.
  • Kininis, M., B. S. Chen, A. G. Diehl, G. D. Isaacs, T. Zhang, A. C. Siepel, A. G. Clark, and W. L. Kraus. 2007. Genomic analyses of transcription factor binding, histone acetylation, and gene expression reveal mechanistically distinct classes of estrogen-regulated promoters. Mol. Cell. Biol. 27:5090–5104.
  • Komarnitsky, P., E. J. Cho, and S. Buratowski. 2000. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 14:2452–2460.
  • Kwek, K. Y., S. Murphy, A. Furger, B. Thomas, W. O'Gorman, H. Kimura, N. J. Proudfoot, and A. Akoulitchev. 2002. U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat. Struct. Biol. 9:800–805.
  • Lacadie, S. A., D. F. Tardiff, S. Kadener, and M. Rosbash. 2006. In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. Genes Dev. 20:2055–2066.
  • Lazarev, D., and J. L. Manley. 2007. Concurrent splicing and transcription are not sufficient to enhance splicing efficiency. RNA 13:1546–1557.
  • Lewis, J. D., E. Izaurralde, A. Jarmolowski, C. McGuigan, and I. W. Mattaj. 1996. A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5′ splice site. Genes Dev. 10:1683–1698.
  • Listerman, I., A. K. Sapra, and K. M. Neugebauer. 2006. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat. Struct. Mol. Biol. 13:815–822.
  • Lonard, D. M., and B. W. O'Malley. 2006. The expanding cosmos of nuclear receptor coactivators. Cell 125:411–414.
  • Mangelsdorf, D. J., C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, P. Chambon, et al. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835–839.
  • Narita, T., T. M. Yung, J. Yamamoto, Y. Tsuboi, H. Tanabe, K. Tanaka, Y. Yamaguchi, and H. Handa. 2007. NELF interacts with CBC and participates in 3′ end processing of replication-dependent histone mRNAs. Mol. Cell 26:349–365.
  • Neugebauer, K. M. 2002. On the importance of being co-transcriptional. J. Cell Sci. 115:3865–3871.
  • Niranjanakumari, S., E. Lasda, R. Brazas, and M. A. Garcia-Blanco. 2002. Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo. Methods 26:182–190.
  • Nunez, E., Y. S. Kwon, K. R. Hutt, Q. Hu, M. D. Cardamone, K. A. Ohgi, I. Garcia-Bassets, D. W. Rose, C. K. Glass, M. G. Rosenfeld, and X. D. Fu. 2008. Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules. Cell 132:996–1010.
  • Palancade, B., and O. Bensaude. 2003. Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation. Eur. J. Biochem. 270:3859–3870.
  • Planas-Silva, M. D., J. L. Donaher, and R. A. Weinberg. 1999. Functional activity of ectopically expressed estrogen receptor is not sufficient for estrogen-mediated cyclin D1 expression. Cancer Res. 59:4788–4792.
  • Pleiss, J. A., G. B. Whitworth, M. Bergkessel, and C. Guthrie. 2007. Rapid, transcript-specific changes in splicing in response to environmental stress. Mol. Cell 27:928–937.
  • Robert, F., M. Blanchette, O. Maes, B. Chabot, and B. Coulombe. 2002. A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly. J. Biol. Chem. 277:9302–9306.
  • Ryser, S., T. Fujita, S. Tortola, I. Piuz, and W. Schlegel. 2007. The rate of c-fos transcription in vivo is continuously regulated at the level of elongation by dynamic stimulus-coupled recruitment of positive transcription elongation factor b. J. Biol. Chem. 282:5075–5084.
  • Sims, R. J., III, S. S. Mandal, and D. Reinberg. 2004. Recent highlights of RNA-polymerase-II-mediated transcription. Curr. Opin. Cell Biol. 16:263–271.
  • Stamm, S., S. Ben-Ari, I. Rafalska, Y. Tang, Z. Zhang, D. Toiber, T. A. Thanaraj, and H. Soreq. 2005. Function of alternative splicing. Gene 344:1–20.
  • Tardiff, D. F., S. A. Lacadie, and M. Rosbash. 2006. A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional. Mol. Cell 24:917–929.
  • Wetterberg, I., G. Bauren, and L. Wieslander. 1996. The intranuclear site of excision of each intron in Balbiani ring 3 pre-mRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns. RNA 2:641–651.
  • Zacharewski, T. R., K. L. Bondy, P. McDonell, and Z. F. Wu. 1994. Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced pS2 expression. Cancer Res. 54:2707–2713.
  • Zhang, H., L. Sun, J. Liang, W. Yu, Y. Zhang, Y. Wang, Y. Chen, R. Li, X. Sun, and Y. Shang. 2006. The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription. EMBO J. 25:4223–4233.

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