The Essential DNA-Binding Protein sap1 of Schizosaccharomyces pombe Contains Two Independent Oligomerization Interfaces That Dictate the Relative Orientation of the DNA-Binding Domain

REFERENCES

• Arcangioli, B., T. D. Copeland, and A. J. S. Klar. 1994. Sap1, a protein that binds to sequences required for mating-type switching, is essential for viability in Schizosaccharomyces pombe. Mol. Cell. Biol. 14:2058–2065.
   PubMedGoogle Scholar
• Arcangioli, B., M. Ghazvini, and V. Ribes. 1994. Identification of the DNA-binding domains of the switch-activating-protein sap1 from S. pombe by random point mutations screening in E. coli. Nucleic Acids Res. 22:2930–2937.
   PubMedGoogle Scholar
• Arcangioli, B., and A. J. S. Klar. 1991. A novel switch-activating site (SAS1) and its cognate binding factor (sap1) required for efficient mat1 switching in Schizosaccharomyces pombe. EMBO J. 10:3025–3032.
   PubMed Web of Science ®Google Scholar
• Arcangioli, B., and B. Lescure. 1985. Identification of proteins involved in the regulation of the yeast iso-1-cytochrome C expression by oxygen. EMBO J. 4:2627–2633.
   PubMedGoogle Scholar
• Brown, D. D. 1984. The role of stable complexes that repress and activate eucaryotic genes. Cell 37:359–365.
   PubMed Web of Science ®Google Scholar
• Egel, R. 1984. The pedigree pattern of mating-type in Schizosaccharomyces pombe. Curr. Genet. 8:205–210.
   PubMedGoogle Scholar
• Fried, M., and D. M. Crothers. 1981. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9:6505–6525.
   PubMed Web of Science ®Google Scholar
• Garner, M. M., and A. Revsin. 1981. A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions. Application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res. 9:3047–3060.
   PubMed Web of Science ®Google Scholar
• Hendrickson, W., and R. Schleif. 1985. A dimer of AraC protein contacts three adjacent major groove regions of the ara1 DNA site. Proc. Natl. Acad. Sci. USA 82:3129–3133.
   PubMed Web of Science ®Google Scholar
• Hope, I. A., and K. Struhl. 1987. GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA. EMBO J. 6:2781–2784.
   PubMed Web of Science ®Google Scholar
• Klar, A. J. S. 1987. Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast. Nature (London) 362: 466–470.
   Google Scholar
• Klar, A. J. S. 1990. The developmental fate of fission yeast cells is determined by the pattern of inheritance of parental and grandparental DNA strands. EMBO J. 9:1407–1415.
   PubMedGoogle Scholar
• Klar, A. J. S., M. Bonaduce, and R. Cafferkey. 1991. The mechanism of fission yeast mating type interconversion: seal/replicate/cleave model of replication across the double-stranded break site at mat1. Genetics 127:489–496.
   PubMedGoogle Scholar
• Kurokawa, R., V. C. Yu, A. Näär, S. Kyakumoto, Z. Han, S. Silverman, M. G. Rosenfeld, and C. K. Glass. 1993. Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev. 7:1423–1435.
   PubMed Web of Science ®Google Scholar
• LeBowitz, J. H., R. G. Clerc, M. Brenowitz, and P. A. Sharp. 1989. The Oct-2 protein binds cooperatively to adjacent octamer sites. Genes Dev. 3:1625–1638.
   PubMedGoogle Scholar
• Mader, S., J. Y. Chen, Z. Chen, J. White, P. Chambon, and H. Gronemeyer. 1993. The patterns of binding of RAR, RXR and T4R homo- and het-erodimers to direct repeats are dictated by the binding specifities of the DNA binding domains. EMBO J. 12:5029–5041.
   PubMed Web of Science ®Google Scholar
• Miyata, H., and M. Miyata. 1981. Modes of conjugation in homothallic cells of Schizosaccharomyces pombe. J. Gen. Appl. Microbiol. 27:365–371.
   Google Scholar
• Perlmann, T., P. N. Ragarajan, K. Umesono, and R. M. Evans. 1993. Determinants for selective RAR and TR recognition of direct repeat HREs. Genes Dev. 7:1411–1422.
   PubMed Web of Science ®Google Scholar
• Rastinejad, F., T. Perlmann, R. M. Evans, and P. B. Sigler. 1995. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature (London) 375:203–211.
   PubMed Web of Science ®Google Scholar
• Ribes, V., and B. Arcangioli. Unpublished data.
   Google Scholar
• Singh, J., and A. J. S. Klar. 1993. DNA polymerase-a is essential for mating-type switching in fission yeast. Nature (London) 361:271–273.
   PubMedGoogle Scholar
• Tsai, S. Y., M. J. Tsai, and B. W. O'Malley. 1989. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell 57:443–448.
   PubMedGoogle Scholar
• Weintraub, H. 1985. Assembly and propagation of repressed and dere-pressed chromosomal states. Cell 42:705–711.
   PubMed Web of Science ®Google Scholar
• Zhang, L., and L. Guarente. 1994. The yeast activator HAP1-a GAL4 family member binds DNA in a directly repeated orientation. Genes Dev. 8:2110–2119.
   PubMedGoogle Scholar