Non-Mendelian, Heritable Blocks to DNA Rearrangement Are Induced by Loading the Somatic Nucleus of Tetrahymena thermophila with Germ Line-Limited DNA

REFERENCES

• Allen, S. L. 1967. Cytogenetics of genomic exclusion in Tetrahymena. Genetics 55:797–822.
   PubMedGoogle Scholar
• Austerberry, C. F., C. D. Allis, and M. C. Yao. 1984. Specific DNA rearrangements in synchronously developing nuclei of Tetrnhymena. Proc. Natl. Acad. Sci. USA 81:7383–7387.
   PubMedGoogle Scholar
• Austerberry, C. F., R. O. Snyder, and M. C. Yao. 1989. Sequence microheterogeneity is generated at junctions of programmed DNA deletions in Tetrahymena thermophila. Nucleic Acids Res. 17:7263–7272.
   PubMedGoogle Scholar
• Austerberry, C. F., and M.-C. Yao. 1987. Nucleotide sequence structure and consistency of a developmentally regulated DNA deletion in Tetrahymena thermophila. Mol. Cell. Biol. 7:435–443.
   PubMedGoogle Scholar
• Austerberry, C. F., and M.-C. Yao. 1988. Sequence structures of two developmentally regulated, alternative DNA deletion junctions in Tetrnhymena thermophila. Mol. Cell. Biol. 8:3947–3950.
   PubMedGoogle Scholar
• Baroin-Tourancheau, A., P. Delgado, R. Perasso, and A. Adoutte. 1992. A broad molecular phylogeny of ciliates: identification of major evolutionary trends and radiations within the phylum. Proc. Natl. Acad. Sci. USA 89:9764–9768.
   PubMedGoogle Scholar
• Chalker, D. L., A. Wilson, A. La Terza, C. Kroenke, and M. C. Yao. Unpublished data.
   Google Scholar
• Doerder, F. P., and M. S. Berkowitz. 1987. Nucleo-cytoplasmic interaction during macronuclear differentiation in ciliate protists: genetic basis for cytoplasmic control of SerH expression during macronuclear development in Tetrahymena thermophila. Genetics 117:13–23.
   PubMedGoogle Scholar
• Duharcourt, S., A. Butler, and E. Meyer. 1995. Epigenetic self-regulation of developmental excision of an internal eliminated sequence in Paramecium tetraurelia. Genes Dev. 9:2065–2077.
   PubMedGoogle Scholar
• Epstein, L. M., and J. D. Forney. 1984. Mendelian and non-Mendelian mutations affecting surface antigen expression in Paramecium tetraurelia. Mol. Cell. Biol. 4:1583–1590.
   PubMed Web of Science ®Google Scholar
• Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
   PubMed Web of Science ®Google Scholar
• Feinberg, A. P., and B. Vogelstein. 1984. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Addendum. Anal. Biochem. 137:266–267.
   PubMed Web of Science ®Google Scholar
• Forney, J. D., and E. H. Blackburn. 1988. Developmentally controlled telomere addition in wild-type and mutant paramecia. Mol. Cell. Biol. 8:251–258.
   PubMedGoogle Scholar
• Gaertig, J., and M. A. Gorovsky. 1992. Efficient mass transformation of Tetrahymena thermophila by electroporation of conjugants. Proc. Natl. Acad. Sci. USA 89:9196–9200.
   PubMedGoogle Scholar
• Godiska, R., C. James, and M. C. Yao. 1993. A distant 10-bp sequence specifies the boundaries of a programmed DNA deletion in Tetrahymena. Genes Dev. 7:2357–2365.
   PubMedGoogle Scholar
• Godiska, R., and M. C. Yao. 1990. A programmed site-specific DNA rearrangement in Tetrahymena thermophila requires flanking polypurine tracts. Cell 61:1237–1246.
   PubMedGoogle Scholar
• Gorovsky, M. A., M. C. Yao, J. B. Keevert, and G. L. Pleger. 1975. Isolation of micro- and macronuclei of Tetrahymena pyriformis. Methods Cell Biol. 9:311–327.
   PubMedGoogle Scholar
• Greenwood, S. J., M. Schlegel, M. L. Sogin, and D. H. Lynn. 1991. Phylogenetic relationships of Blepharisma americanum and Colpoda inflata within the phylum Ciliophora inferred from complete small subunit rRNA gene sequences. J. Protozool. 38:1–6.
   PubMedGoogle Scholar
• Harumoto, T. 1986. Induced change in a non-Mendelian determinant by transplantation of macronucleoplasm in Paramecium tetraurelia. Mol. Cell. Biol. 6:3498–3501.
   PubMedGoogle Scholar
• Katoh, M., M. Hirono, T. Takemasa, M. Kimura, and Y. Watanabe. 1993. A micronucleus-specific sequence exists in the 5′-upstream region of calmodulin gene in Tetrahymena thermophila. Nucleic Acids Res. 21:2409–2414.
   PubMedGoogle Scholar
• Kim, C. S., J. R. Preer, and B. Polisky. 1994. Identification ofDNAsegments capable of rescuing a non-Mendelian mutant in Paramecium. Genetics 136:1325–1328.
   PubMedGoogle Scholar
• Larson, D. D., E. H. Blackburn, P. C. Yeager, and E. Orias. 1986. Control of rDNA replication in Tetrahymena involves a cis-acting upstream repeat of a promoter element. Cell 47:229–240.
   PubMedGoogle Scholar
• McDonald, B. B. 1966. The exchange of RNA and protein during conjugation in Tetrahymena. J. Protozool. 13:277–285.
   PubMedGoogle Scholar
• Prescott, D. M. 1994. The DNA of ciliated protozoa. Microbiol. Rev. 58:233–267.
   PubMedGoogle Scholar
• Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Seifert, H. S., E. Y. Chen, M. So, and F. Hefron. 1986. Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 83:735–739.
   PubMedGoogle Scholar
• Sonneborn, T. M. 1977. Genetics of cellular differentiation: stable nuclear differentiation in eukaryotic unicells. Annu. Rev. Genet. 11:349–367.
   PubMed Web of Science ®Google Scholar
• Tondravi, M. M., and M. C. Yao. 1986. Transformation of Tetrahymena thermophila by microinjection of ribosomal RNA genes. Proc. Natl. Acad. Sci. USA 83:4369–4373.
   PubMedGoogle Scholar
• Ward, J., and M.-C. Yao. Unpublished data.
   Google Scholar
• Wenkert, D., and C. D. Allis. 1984. Timing of the appearance of macronuclear-specific histone variant hv1 and gene expression in developing new macronuclei of Tetrahymena thermophila. J. Cell Biol. 98:2107–2117.
   PubMedGoogle Scholar
• Yao, C.-H., and M.-C. Yao. Unpublished data.
   Google Scholar
• Yao, M.-C. 1982. Amplification of ribosomal RNA gene in Tetrahymena, p. 127–153. In H. Busch and L. Rothblum (ed.), The cell nucleus, vol. 12. Academic Press, Inc., New York.
   Google Scholar
• Yao, M.-C. 1989. Site-specific chromosome breakage and DNA deletion in ciliates, p. 715–734. In D. E. Berg and M. M. Howe (ed.), Mobile DNA. American Society for Microbiology, Washington, D.C.
   Google Scholar
• Yao, M. C., J. Choi, S. Yokoyama, C. F. Austerberry, and C. H. Yao. 1984. DNA elimination in Tetrahymena: a developmental process involving extensive breakage and rejoining of DNA at defined sites. Cell 36:433–440.
   PubMedGoogle Scholar
• Yao, M. C., and J. G. Gall. 1977. A single integrated gene for ribosomal RNA in a eucaryote, Tetrahymena pyriformis. Cell 12:121–132.
   PubMedGoogle Scholar
• Yao, M. C., and M. A. Gorovsky. 1974. Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis. Chromosoma 48:1–18.
   PubMedGoogle Scholar
• Yao, M. C., A. R. Kimmel, and M. A. Gorovsky. 1974. A small number of cistrons for ribosomal RNA in the germinal nucleus of a eukaryote, Tetrahymena pyriformis. Proc. Natl. Acad. Sci. USA 71:3082–3086.
   PubMedGoogle Scholar
• Yao, M.-C., and C.-H. Yao. 1989. Accurate processing and amplification of cloned germ line copies of ribosomal DNA injected into developing nuclei of Tetrahymena thermophila. Mol. Cell. Biol. 9:1092–1099.
   PubMedGoogle Scholar
• You, Y., J. Scott, and J. Forney. 1994. The role of macronuclear DNA sequences in the permanent rescue of a non-Mendelian mutation in Paramecium tetraurelia. Genetics 136:1319–1324.
   PubMedGoogle Scholar