HOXB7 Constitutively Activates Basic Fibroblast Growth Factor in Melanomas

REFERENCES

• Adema, G. J., A. J. De Boer, R. van’t Hullenaar, M. Denijn, D. J. Ruiter, A. M. Vogel, and C. G. Figdor. 1993. Melanocyte lineage-specific antigens recognized by monoclonal antibodies NKI-beteb, HMB-50, and HMB-45 are encoded by a single c-DNA. Am. J. Pathol. 143:1579–1585.
   PubMed Web of Science ®Google Scholar
• Anichini, A., R. Mortarini, G. Fossati, and G. Parmiani. 1986. Phenotype profile of clones from early cultures of human metastatic melanomas and its modulation by recombinant interferon γ. Int. J. Cancer 38:505–511.
   PubMedGoogle Scholar
• Asselineau, D., B. A. Bernard, C. Bailly, and M. Darmon. 1989. Retinoic acid improves epidermal morphogenesis. Dev. Biol. 133:322–335.
   PubMed Web of Science ®Google Scholar
• Balling, R., G. Mutter, P. Gruss, and M. Kessll. 1989. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox 1.1 in transgenic mice. Cell 58:337–347.
   PubMed Web of Science ®Google Scholar
• Beck, Y., R. Oren, B. Amit, A. Levanon, M. Gorecki, and J. R. Hartman. 1987. Human Mn superoxide dismutase cDNA sequence. Nucleic Acids Res. 15:9076.
   PubMed Web of Science ®Google Scholar
• Becker, D., C. B. Meier, and M. Herlyn. 1989. Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor. EMBO J. 8:3685–3691.
   PubMed Web of Science ®Google Scholar
• Bieberich, C. J., F. H. Ruddle, and K. S. Stenn. 1992. Differential expression of the 3.1 gene in adult mouse skin. Ann. N. Y. Acad. Sci. 642:346–354.
   Google Scholar
• Blatt, C., J. Lotem, and L. Sachs. 1992. Inhibition of specific pathways of myeloid cell differentiation by an activated Hox 2.4 homeobox gene. Cell Growth Differ. 6:671–676.
   Google Scholar
• Bordoni, R., R. Fine, D. Murray, and A. Richmond. 1990. Characterization of the role of melanoma growth stimulatory activity (MGSA) in the growth of normal melanocytes, nevocytes, and malignant melanocytes. J. Cell. Bio-chem. 44:207–219.
   PubMed Web of Science ®Google Scholar
• Carè, A., G. Mattia, E. Montesoro, I. Parolini, G. Russo, M. P. Colombo, and C. Peschle. 1994. c-fes expression in ontogenetic development and hematopoietic differentiation. Oncogene 9:739–747.
   PubMedGoogle Scholar
• Carè, A., U. Testa, A. Bassani, E. Tritarelli, E. Montesoro, P. Samoggia, L. Cianetti, and C. Peschle. 1994. Coordinate expression and proliferative role ofHOXB genes in activated adult T lymphocytes. Mol. Cell. Biol. 14:4872–4877.
   PubMedGoogle Scholar
• Cillo, C., P. Barba, G. Freschi, G. Bucciarelli, M. C. Magli, and E. Boncinelli. 1992. HOX gene expression in normal and neoplastic human kidney. Int. J. Cancer 51:892–897.
   PubMed Web of Science ®Google Scholar
• Colombo, M. P., C. Maccalli, S. Mattei, C. Melani, M. Radrizzani, and G. Parmiani. 1992. Expression of cytokine genes, including IL-6, in human melanoma cell lines. Melanoma Res. 2:181–189.
   PubMedGoogle Scholar
• Condie, B. G., and M. R. Capecchi. 1994. Mice with targeted disruptions in the paralogous genes hoxa-3 and hod-3 reveal synergistic interaction. Nature (London) 370:304–307.
   PubMedGoogle Scholar
• Dedera, D. A., E. K. Waller, D. P. LeBrun, A. Sen-Majumdar, M. E. Stevens, G. S. Barsh, and M. L. Cleary. 1993. Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice. Cell 74:833–838.
   PubMed Web of Science ®Google Scholar
• Deguchi, Y., and J. H. Kehre. 1993. High level expression of the homeobox gene HB24 in a human T-cell line confers the ability to form tumors in nude mice. Cancer Res. 53:373–377.
   PubMedGoogle Scholar
• Deguchi, Y., J. F. Moroney, and J. H. Kehrl. 1991. Expression of the HOX-2.3 homeobox gene in human lymphocytes and lymphoid tissues. Blood 78:445–450.
   PubMedGoogle Scholar
• Deschamps, J., and F. Meijlink. 1992. Mammalian homeobox genes in normal development and neoplasia. Crit. Res. Oncol. 3:117–173.
   Google Scholar
• De Vita, G., P. Barba, N. Odartchenko, J.-C. Givel, G. Freschi, G. Bucciarelli, M. C. Magli, E. Boncinelli, and C. Cillo. 1993. Expression of homeobox containing genes in primary and metastatic colorectal cancer. Eur. J. Cancer 29A:887–893.
   PubMedGoogle Scholar
• Edelmann, G. M., and F. S. Jones. 1993. Outside and downstream of the homeobox. J. Biol. Chem. 268:20683–20685.
   PubMedGoogle Scholar
• Flamme, I., and W. Risau. 1992. Induction of vasculogenesis and hemato-poiesis in vitro. Development 116:435–439.
   PubMed Web of Science ®Google Scholar
• Florkievitcz, R. Z., F. Shibata, T. Barankiewicz, A. Baird, A.-M. Gonzales, E. Florkiewicz, and N. Shah. 1991. Basic fibroblast growth factor gene expression. Ann. N. Y. Acad. Sci. 638:109–126.
   PubMedGoogle Scholar
• Giampaolo, A., P. Sterpetti, D. Bulgarini, P. Samoggia, E. Pelosi, M. Valt-ieri, and C. Peschle. 1994. Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation. Blood 84:3637–3647.
   PubMed Web of Science ®Google Scholar
• Giard, D. J., S. A. Aaorson, G. J. Todaro, P. Arnstein, J. H. Kersey, H. Dosik, and W. P. Parks. 1973. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J. Natl. Cancer Inst. 51:1417–1423.
   PubMed Web of Science ®Google Scholar
• Goomer, R. S., B. D. Holst, I. C. Wood, F. S. Jones, and G. M. Edelmann. 1994. Regulation in vitro of an L-CAM enhancer by homeobox genes HOXD9 and HNF-1. Proc. Natl. Acad. Sci. USA 91:7985–7989.
   PubMedGoogle Scholar
• Halaban, R., B. S. Kwon, S. Ghosh, P. Delli Bovi, and A. Baird. 1988. bFGF as an autocrine growth factor for human melanoma. Oncogene Res. 3:177–186.
   PubMedGoogle Scholar
• Hatano, M., C. W. M. Roberts, M. Minden, W. N. Crist, and S. J. Korsmeyer. 1991. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 253:79–82.
   PubMed Web of Science ®Google Scholar
• Herlyn, M., D. Guerry, and H. Koprowsky. 1985. Recombinant γ-interferon induced changes in expression and shedding of antigens associated with normal human melanocytes, nevus cells, and primary and metastatic melanoma cells. J. Immunol. 134:4226–4230.
   PubMedGoogle Scholar
• Herlyn, M., J. Thurin, G. Balaban, J. L. Bennicelli, D. Herlyn, D. E. Elder, E. Bondi, G. DuPont, P. Nowell, W. H. Clark, and H. Koproski. 1985. Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res. 45:5670–5676.
   PubMed Web of Science ®Google Scholar
• Jones, F. S., G. Chalepakis, P. Gruss, and G. M. Edelmann. 1992. Activation of the cytotactin promoter by the homeobox-containing gene Evx-1. Proc. Natl. Acad. Sci. USA 89:2091–2095.
   PubMed Web of Science ®Google Scholar
• Jones, F. S., B. D. Holst, O. Minowa, E. M. De Robertis, and G. M. Edelmann. 1993. Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HOX C6 (HOX-3.3). Proc. Natl. Acad. Sci. USA 90:6557–6561.
   PubMedGoogle Scholar
• Jones, F. S., E. A. Prediger, D. A. Bittner, E. M. De Robertis, and G. M. Edelmann. 1992. Cell adhesion molecules as targets for HOX genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with HOX-2.5 and 2.4. Proc. Natl. Acad. Sci. USA 89:2086–2090.
   PubMed Web of Science ®Google Scholar
• Kalionis, B., and P. H. O’Farrell. 1993. Universal target sequence is bound in vitro by diverse homeodomains. Mech. Dev. 43:57–70.
   PubMedGoogle Scholar
• Kerbel, R. S. 1992. Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Am. J. Pathol. 141:519–524.
   PubMed Web of Science ®Google Scholar
• Kerbel, R. S., M. S. Man, and D. Dexter. 1984. A model of human cancer metastasis: extensive spontaneous and artificial metastasis of a human pigmented melanoma and derived variant sublines in nude mice. J. Natl. Cancer Inst. 72:93–101.
   PubMedGoogle Scholar
• Kozlowsky, J. M., I. J. Fidler, D. Campbell, Z.-I. Xu, M. E. Kaighn, and I. R. Hart. 1984. Metastatic behaviour of human tumor cell lines grown in the nude mouse. Cancer Res. 44:3522–3529.
   PubMedGoogle Scholar
• Krumlauf, R. 1994. HOX genes invertebrate development. Cell 78:191–201.
   PubMed Web of Science ®Google Scholar
• Lawrence, H. J., and C. Largman. 1992. Homeobox genes in normal hema-topoiesis and leukemia. Blood 80:2445–2453.
   PubMed Web of Science ®Google Scholar
• Magli, M. C., P. Barba, A. Celetti, G. De Vita, C. Cillo, and E. Boncinelli. 1991. Coordinate regulation of HOX genes in human hematopoietic cells. Proc. Natl. Acad. Sci. USA 88:6348–6352.
   PubMed Web of Science ®Google Scholar
• Mattei, S., M. P. Colombo, C. Melani, A. Silvani, G. Parmiani, and M. Herlyn. 1994. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int. J. Cancer 56:853–857.
   PubMed Web of Science ®Google Scholar
• Matthews, C. H. E., K. Detmer, H. J. Lawrence, and C. Largman. 1993. Expression of the Hox 2.2 homeobox gene in murine embryonic epidermis. Differentiation 52:177–184.
   PubMedGoogle Scholar
• Maulbecker, C. C., and P. Gruss. 1993. The oncogenic potential of deregulated homeobox genes. Cell Growth Differ. 4:431–441.
   PubMedGoogle Scholar
• Mavilio, F. 1993. Regulation of homeo-box containing genes by morphogens. Eur. J. Biochem. 212:273–288.
   PubMedGoogle Scholar
• McGregor, G. R., and C. T. Caskey. 1989. Construction of plasmids that express E. coli β-galactosidase in mammalian cells. Nucleic Acids Res. 17:2365.
   PubMedGoogle Scholar
• Perkins, A., K. Kongsuwan, J. Visvader, J. M. Adams, and S. Cory. 1990. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc. Natl. Acad. Sci. USA 87:8398–8402.
   PubMed Web of Science ®Google Scholar
• Perkins, A. C., and S. Cory. 1993. Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene. EMBO J. 12:3835–3846.
   PubMedGoogle Scholar
• Petrini, M., M. T. Quaranta, U. Testa, P. Samoggia, E. Tritarelli, A. Carè, L. Cianetti, M. Valtieri, C. Barletta, and C. Peschle. 1992. Expression of selected human HOX-2 genes in B/T acute lymphoid leukemia and IL-2/IL-1β-stimulated natural killer lymphocytes. Blood 80:185–193.
   PubMed Web of Science ®Google Scholar
• Pollock, R. A., T. Sreenath, L. Ngo, and C. J. Bieberich. 1995. Gain of function mutations for paralogous Hox genes: implications for the evolution of Hox gene function. Proc. Natl. Acad. Sci. USA 92:4492–4496.
   PubMedGoogle Scholar
• Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Sauvageau, G., P. M. Lansdorp, C. J. Eaves, D. E. Hogge, W. H. Dragowska, D. S. Reid, C. Largman, H. J. Lawrence, and R. K. Humphries. 1994. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc. Natl. Acad. Sci. USA 91:12223–12227.
   PubMed Web of Science ®Google Scholar
• Schadendorf, D., A. Moller, B. Algermissen, M. Worm, M. Sticherling, and B. M. Czarnetzki. 1993. IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor. J. Immunol. 151:2667–2675.
   PubMed Web of Science ®Google Scholar
• Schweigerer, L., G. Neufeld, A. Mergia, J. A. Abraham, J. C. Fiddes, and D. Gospodarowicz. 1987. Basic fibroblast growth factor in human rhabdomyosarcoma cells: implication for the proliferation and neovascularization of myoblast-derived tumors. Proc. Natl. Acad. Sci. USA 84:842–846.
   PubMedGoogle Scholar
• Scott, G. A., and L. A. Goldsmith. 1993. Homeobox genes and skin development: a review. J. Invest. Dermatol. 101:3–8.
   PubMedGoogle Scholar
• Scott, M. P. 1992. Vertebrate homeobox gene nomenclature. Cell 71:551–553.
   PubMed Web of Science ®Google Scholar
• Simeone, A., F. Mavilio, D. Acampora, A. Giampaolo, A. Faiella, V. Zappa-vigna, M. D’Esposito, M. Pannese, G. Russo, E. Boncinelli, and C. Peschle. 1987. Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development. Proc. Natl. Acad. Sci. USA 84:4914–4918.
   PubMedGoogle Scholar