The POU Domain of SCIP/Tst-1/Oct-6 Is Sufficient for Activation of an Acetylcholine Receptor Promoter

REFERENCES

• Anderson, B., M. D. Schonemann, R. V. Pearse II, K. Jenne, J. Sugarman, and M. G. Rosenfeld. 1993. Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex. J. Biol. Chem. 268:23390–23398.
   PubMedGoogle Scholar
• Bodner, M., J.-L. Castrillo, L. E. Theill, T. Deerinck, M. Ellisman, and M. Karin. 1988. The pituitary-specific transcription factor GHF-1 is a ho-meobox-containing protein. Cell 55:505–518.
   PubMed Web of Science ®Google Scholar
• Catron, K. M., H. Zhang, S. C. Marshall, J. A. Inostroza, J. M. Wilson, and C. Abate. 1995. Transcriptional repression by Msx-1 does not require home-odomain DNA-binding sites. Mol. Cell. Biol. 15:861–871.
   PubMed Web of Science ®Google Scholar
• Das, G., C. S. Hinkley, and W. Herr. 1995. Basal promoter elements as a selective determinant of transcriptional activator function. Nature (London) 374:657–660.
   PubMedGoogle Scholar
• Dechesne, C. A., Q. Wei, J. Eldridge, L. Gannoun-Zaki, P. Millasseau, L. Bougueleret, D. Caterina, and B. M. Paterson. 1994. E-box and MEF-2-independent muscle-specific expression, positive autoregulation, and cross-activation of the chicken MyoD (CMD1) promoter reveal an indirect regulatory pathway. Mol. Cell. Biol. 14:5474–5486.
   PubMedGoogle Scholar
• Faus, I., H.-J. Hsu, and E. Fuchs. 1994. Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia. Mol. Cell. Biol. 14:3263–3275.
   PubMedGoogle Scholar
• Gerrero, M. R., R. J. McEvilly, E. Turner, C. R. Lin, S. O’Connell, K. J. Jenne, M. V. Hobbs, and M. G. Rosenfeld. 1993. Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc. Natl. Acad. Sci. USA 90:10841–10845.
   PubMedGoogle Scholar
• Gerster, T., C.-G. Balmaceda, and R. G. Roeder. 1990. The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. EMBO J. 9:1635–1643.
   PubMedGoogle Scholar
• Greene, L. A., and A. S. Tischler. 1982. PC12 pheochromocytoma cell in neurobiology research. Adv. Cell Neurobiol. 3:373–414.
   Google Scholar
• Grueneberg, D. A., S. Natesan, C. Alexandre, and M. Z. Gilman. 1992. Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor. Science 257:1089–1095.
   PubMed Web of Science ®Google Scholar
• Hayashi, S., and M. P. Scott. 1990. What determines the specificity of action of Drosophila homeodomain proteins? Cell 63:883–894.
   PubMedGoogle Scholar
• He, X., R. Gerrero, D. M. Simmons, R. E. Park, C. R. Lin, L. W. Swanson, and M. G. Rosenfeld. 1991. Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. Mol. Cell. Biol. 11:1739–1744.
   PubMedGoogle Scholar
• Hernandez, N., and R. Lucito. 1988. Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3′ end formation. EMBO J. 7:3125–3134.
   PubMedGoogle Scholar
• Herr, W., R. A. Strum, R. G. Clerc, L. M. Corcoran, D. Baltimore, P. A. Sharp, H. A. Ingraham, M. G. Rosenfeld, M. Finney, G. Ruvkun, and H. R. Horvitz. 1988. The POU-domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2:1513–1516.
   PubMed Web of Science ®Google Scholar
• Ingraham, H. A., R. Chen, H. J. Mangalam, H. P. Elsholtz, S. E. Flynn, C. R. Lin, D. M. Simmons, L. Swanson, and M. G. Rosenfeld. 1988. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell 55:519–529.
   PubMed Web of Science ®Google Scholar
• Ingraham, H. A., S. E. Flynn, J. W. Voss, V. R. Albert, M. S. Kapiloff, L. Wilson, and M. G. Rosenfeld. 1990. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-depen-dent Pit-1-Pit-1 interactions. Cell 61:1021–1033.
   PubMed Web of Science ®Google Scholar
• Johnson, D. G., L. Carayannopoulos, J. D. Capra, P. W. Tucker, and J. H. Hanke. 1990. The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes. Mol. Cell. Biol. 10:982–990.
   PubMedGoogle Scholar
• Klemm, J. D., M. A. Rould, R. Aurora, W. Herr, and C. O. Pabo. 1994. Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77:21–32.
   PubMed Web of Science ®Google Scholar
• LeBowitz, J. H., T. Kobayashi, L. Staudt, D. Baltimore, and P. A. Sharp. 1988. Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro. Gene Dev. 2:1227–1237.
   PubMedGoogle Scholar
• Lenardo, M., J. Pierce, and D. Baltimore. 1987. Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 236:1573–1577.
   PubMed Web of Science ®Google Scholar
• Li, P., X. He, M. R. Gerrero, M. Mok, A. Aggarwal, and M. G. Rosenfeld. 1993. Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Genes Dev. 7:2483–2496.
   PubMedGoogle Scholar
• Mathis, J. M., D. M. Simmons, X. He, L. W. Swanson, and M. G. Rosenfeld. 1992. Brain-4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 11:2551–2561.
   PubMed Web of Science ®Google Scholar
• Meijer, D., A. Graus, and G. Grosveld. 1992. Mapping the transactivation domain of the Oct-6 POU transcription factor. Nucleic Acids Res. 20:2241–2247.
   PubMedGoogle Scholar
• Meijer, D., A. Graus, R. Kraay, A. Langeveld, M. P. Mulder, and G. Grosveld. 1990. The octamer binding factor Oct-6: cDNA cloning and expression in early embryonic cells. Nucleic Acids Res. 18:7357–7365.
   PubMedGoogle Scholar
• Monuki, E., R. Kuhn, and G. Lemke. 1993. Repression of the myelin P0 gene by the POU transcription factor SCIP. Mech. Dev. 42:15–32.
   PubMedGoogle Scholar
• Monuki, E., R. Kuhn, and G. Lemke. 1993. Cell-specific action and mutable structure of a transcription factor effector domain. Proc. Natl. Acad. Sci. USA 90:9978–9982.
   PubMedGoogle Scholar
• Monuki, E., R. Kuhn, G. Weinmaster, B. D. Trapp, and G. Lemke. 1990. Expression and activity of the POU transcription factor SCIP. Science 249:1300–1303.
   PubMedGoogle Scholar
• Müller, M. M., S. Ruppert, W. Schaffner, and P. Matthias. 1988. A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature (London) 336:544–551.
   PubMedGoogle Scholar
• Müller-Immergluck, M. M., W. Schaffner, and P. Matthias. 1990. Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not a remote enhancer position in non-lymphoid (HeLa) cells. EMBO J. 9:1625–1634.
   PubMedGoogle Scholar
• Murphy, S., J.-B. Yoon, T. Gerster, and R. G. Roeder. 1992. Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol. Cell. Biol. 12:3247–3261.
   PubMed Web of Science ®Google Scholar
• Nelson, C., V. R. Albert, H. P. Elsholtz, L. I.-W. Lu, and M. G. Rosenfeld. 1988. Activation of cell-specific expression of rat growth hormone and pro-lactin genes by a common transcription factor. Science 239:1400–1405.
   PubMed Web of Science ®Google Scholar
• Okamoto, K., H. Okazawa, A. Okuda, M. Sakai, M. Muramatsu, and H. Hamada. 1990. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60:461–472.
   PubMed Web of Science ®Google Scholar
• Renner, K., H. Leger, and M. Wegner. 1994. The POU domain protein Tst-1 and papovaviral large tumor antigen function synergistically to stimulate glia-specific gene expression of JC virus. Proc. Natl. Acad. Sci. USA 91:6433–6437.
   PubMedGoogle Scholar
• Riggs, K. J., S. Saleque, K.-K. Wong, K. T. Merrel, J.-S. Lee, Y. Shi, and K. Calame. 1993. Yin-yang 1 activates the c-myc promoter. Mol. Cell. Biol. 13:7487–7495.
   PubMed Web of Science ®Google Scholar
• Rosenfeld, M. G. 1991. POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev. 5:897–907.
   PubMed Web of Science ®Google Scholar
• Sauer, F., S. K. Hansen, and R. Tjian. 1995. Multiple TAFIIs directing synergistic activation of transcription. Science 270:1783–1788.
   PubMed Web of Science ®Google Scholar
• Scheidereit, C., A. Heguy, and R. G. Roeder. 1987. Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro. Cell 51:783–793.
   PubMed Web of Science ®Google Scholar
• Schöler, H. R., G. R. Dressler, R. Balling, H. Rohdewohld, and P. Gruss. 1990. Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J. 9:2185–2195.
   PubMed Web of Science ®Google Scholar
• Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffer. 1989. Rapid detection of octamer binding proteins with “mini-extracts”, prepared from a small number of cells. Nucleic Acids Res. 17:6419.
   PubMed Web of Science ®Google Scholar
• Stern, S., and W. Herr. 1991. The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain. Genes Dev. 5:2555–2666.
   PubMedGoogle Scholar
• Stern, S., M. Tanaka, and W. Herr. 1989. The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature (London) 341:624–630.
   PubMed Web of Science ®Google Scholar
• Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497–506.
   PubMed Web of Science ®Google Scholar
• Sturm, R. A., and W. Herr. 1988. The POU domain is a bipartite DNA-binding structure. Nature (London) 336:601–604.
   PubMed Web of Science ®Google Scholar
• Suzuki, N., H. Rohdewohld, T. Neuman, P. Gruss, and H. R. Schöler. 1990. Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. EMBO J. 9:3723–3732.
   PubMedGoogle Scholar
• Tanaka, M., and W. Herr. 1990. Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation. Cell 60:375–386.
   PubMedGoogle Scholar
• Tanaka, M., J.-S. Lai, and W. Herr. 1992. Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter. Cell 68:755–767.
   PubMed Web of Science ®Google Scholar
• Treacy, M. N., and M. G. Rosenfeld. 1992. Expression of a family of POU-domain protein regulatory genes during development of the central nervous system. Annu. Rev. Neurosci. 15:139–165.
   PubMed Web of Science ®Google Scholar
• Verrijzer, C. P., and P. C. Van der Vliet. 1993. POU domain transcription factors. Biochim. Biophys. Acta 1173:1–21.
   PubMedGoogle Scholar
• Voss, J. W., L. Wilson, and M. G. Rosenfeld. 1991. POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 5:1309–1320.
   PubMed Web of Science ®Google Scholar
• Walker, S., S. Hayes, and P. O’Hare. 1994. Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16). Cell 79:841–852.
   PubMedGoogle Scholar
• Wegner, M., D. W. Drolet, and M. G. Rosenfeld. 1993. Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy. Proc. Natl. Acad. Sci. USA 90:4743–4747.
   PubMedGoogle Scholar
• Wegner, M., D. W. Drolet, and M. G. Rosenfeld. 1993. POU-domain proteins: structure and function of developmental regulators. Curr. Opin. Cell Biol. 5:488–498.
   PubMedGoogle Scholar
• Weinstein, D. E., P. G. Burrola, and G. Lemke. 1995. Premature Schwann cell differentiation and hypermyelination in mice expressing a targeted antagonist of the POU transcription factor SCIP. Mol. Cell. Neurosci. 6:212–229.
   PubMedGoogle Scholar
• Wirth, T., L. Staudt, and D. Baltimore. 1987. An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature (London) 329:174–178.
   PubMed Web of Science ®Google Scholar
• Yang, X., D. Fyodorov, and E. Deneris. 1995. Transcriptional analysis of acetylcholine receptor a3 gene promoter motifs that bind Sp1 and AP2. J. Biol. Chem. 270:8514–8520.
   PubMedGoogle Scholar
• Yang, X., J. McDonough, D. Fyodorov, M. Morris, F. Wang, and E. S. Deneris. 1994. Characterization of an acetylcholine receptor α3 gene promoter and its activation by the POU-domain factor, SCIP/Tst-1. J. Biol. Chem. 269:10252–10264.
   PubMedGoogle Scholar