Surprising Deficiency of CENP-B Binding Sites in African Green Monkey α-Satellite DNA: Implications for CENP-B Function at Centromeres

REFERENCES

• Agard, D. A., Y. Hiraoka, P. J. Shaw, and J. W. Sedat. 1989. Fluorescence microscopy in three dimensions. Methods Cell Biol. 30:353–377.
   PubMedGoogle Scholar
• Alexandrov, I. A., T. D. Mashkova, T. A. Akopian, L. I. Medvedev, L. L. Kisselev, S. P. Mitkevich, and Y. B. Yurov. 1991. Chromosome-specific alpha satellites: two distinct families on human chromosome 18. Genomics 11:15–23.
   PubMedGoogle Scholar
• Alexandrov, I. A., L. I. Medvedev, L. L. Kisselev, L. Y. Romanova, and Y. B. Yurov. 1993. Definition of a new alpha satellite suprachromosomal family characterized by monomeric organization. Nucleic Acids Res. 21:2209–2215.
   PubMedGoogle Scholar
• Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1991. Current protocols in molecular biology. John Wiley & Sons, New York.
   Google Scholar
• Bernat, R. L. Ph.D. thesis. Johns Hopkins University School of Medicine, Baltimore, Md.
   Google Scholar
• Blennow, E., H. Telenius, D. de Vos, C. Larsson, P. Henriksson, Ö. Johan-son, N. P. Carter, and M. Nordenskjöld. 1994. Tetrasomy 15q: two marker chromosomes with no detectable alpha-satellite DNA. Am. J. Hum. Genet. 54:877–883.
   PubMedGoogle Scholar
• Broccoli, D., K. T. Trevor, O. J. Miller, and D. A. Miller. 1991. Isolation of a variant family of mouse minor satellite DNA that hybridizes preferentially to chromosome 4. Genomics 10:68–74.
   PubMedGoogle Scholar
• Cai, M., and R. W. Davis. 1990. Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine protrophy. Cell 61:437–446.
   PubMed Web of Science ®Google Scholar
• Choo, K. H., B. Vissel, A. Nagy, E. Earle, and P. Kalitsis. 1991. A survey of the genomic distribution of alpha satellite DNA on all human chromosomes, and derivation of a new consensus sequence. Nucleic Acids Res. 19:1179–1182.
   PubMedGoogle Scholar
• Clarke, L., and J. Carbon. 1980. Isolation of a yeast centromere and construction of functional small circular chromosomes. Nature (London) 287:504–509.
   PubMed Web of Science ®Google Scholar
• Cooke, C. A., D. P. Bazett-Jones, W. C. Earnshaw, and J. B. Rattner. 1993. Mapping DNA within the mammalian kinetochore. J. Cell Biol. 120:1083–1091.
   PubMedGoogle Scholar
• Cooke, C. A., R. L. Bernat, and W. C. Earnshaw. 1990. CENP-B: a major human centromere protein located beneath the kinetochore. J. Cell Biol. 110:1475–1488.
   PubMed Web of Science ®Google Scholar
• Cooke, C. A., M. M. S. Heck, and W. C. Earnshaw. 1987. The INCENP antigens: movement from the inner centromere to the midbody during mitosis. J. Cell Biol. 105:2053–2067.
   PubMed Web of Science ®Google Scholar
• Doak, T. G., F. P. Doerder, C. L. Jahn, and G. Herrick. 1994. A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common “D35E” motif. Proc. Natl. Acad. Sci. USA 91:942–946.
   PubMed Web of Science ®Google Scholar
• Doheny, K. F., P. K. Sorger, A. A. Hyman, S. Tugendreich, F. Spencer, and P. Hieter. 1993. Identification of essential components of the S. cerevisiae kinetochore. Cell 73:761–774.
   PubMedGoogle Scholar
• Earnshaw, W. C., R. L. Bernat, C. A. Cooke, and N. F. Rothfield. 1991. Role of the centromere/kinetochore in cell cycle control. Cold Spring Harbor Symp. Quant. Biol. 56:675–685.
   PubMedGoogle Scholar
• Earnshaw, W. C., H. Ratrie, and G. Stetten. 1989. Visualization of centromere proteins CENP-B and CENP-C on a stable dicentric chromosome in cytological spreads. Chromosoma 98:1–12.
   PubMedGoogle Scholar
• Earnshaw, W. C., and N. Rothfield. 1985. Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma 91:313–321.
   PubMed Web of Science ®Google Scholar
• Earnshaw, W. C., K. F. Sullivan, P. S. Machlin, C. A. Cooke, D. A. Kaiser, T. D. Pollard, N. F. Rothfield, and D. W. Cleveland. 1987. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J. Cell Biol. 104:817–829.
   PubMed Web of Science ®Google Scholar
• Earnshaw, W. C., and J. Zackowski. Unpublished data.
   Google Scholar
• Ellis, L., E. Clauser, D. O. Morgan, M. Edery, R. A. Roth, and W. J. Rutter. 1986. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglu-cose. Cell 45:721–732.
   PubMed Web of Science ®Google Scholar
• Fitzgerald, D. J., G. L. Dryden, E. C. Bronson, J. S. Williams, and J. N. Anderson. 1994. Conserved patterns of bending in satellite and nucleosome positioning DNA. J. Biol. Chem. 269:21303–21314.
   PubMed Web of Science ®Google Scholar
• Gruss, P., and G. Sauer. 1975. Repetitive primate DNA containing the recognition sequences for two restriction endonucleases which generate cohesive ends. FEBS Lett. 60:85–88.
   PubMedGoogle Scholar
• Guldner, H. H., H.-J. Lakomek, and F. A. Bautz. 1984. Human anti-centromere sera recognise a 19.5 kD non-histone chromosomal protein from HeLa cells. Clin. Exp. Immunol. 58:13–20.
   PubMedGoogle Scholar
• Haaf, T., A. G. Matera, J. Wienberg, and D. C. Ward. 1995. Presence and abundance of CENP-B box sequences in great ape subsets of primate-specific alpha-satellite DNA. J. Mol. Evol. 41:487–491.
   PubMedGoogle Scholar
• Haaf, T., P. E. Warburton, and H. F. Willard. 1992. Integration of human a-satellite DNA into simian chromosomes: centromere protein binding and disruption of normal chromosome segregation. Cell 70:1–20.
   PubMedGoogle Scholar
• Hayashi, T., H. Ohtsuka, K. Kuwabara, Y. Mafune, N. Miyashita, K. Mori-waki, Y. Takahashi, and R. Kominami. 1993. A variant family of mouse minor satellite located on the centromeric region of chromosome 2. Genomics 17:490–492.
   PubMedGoogle Scholar
• Hyman, A. A., K. Middleton, M. Centola, T. J. Mitchison, and J. Carbon. 1992. Microtubule-motor activity of a yeast centromere-binding protein complex. Nature (London) 359:533–536.
   PubMed Web of Science ®Google Scholar
• Ikeno, M., H. Masumoto, and T. Okazaki. 1994. Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range alpha-satellite DNA arrays of human chromosome 21. Hum. Mol. Genet. 3:1245–1257.
   PubMedGoogle Scholar
• Jiang, W., J. Lechner, and J. Carbon. 1993. Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore. J. Cell Biol. 121:513–519.
   PubMedGoogle Scholar
• Jiang, W., K. Middleton, H.-J. Yoon, C. Fouquet, and J. Carbon. 1993. An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules. Mol. Cell. Biol. 13:4884–4893.
   PubMed Web of Science ®Google Scholar
• Kipling, D., A. R. Mitchell, H. Masumoto, H. E. Wilson, L. Nicol, and H. J. Cooke. 1995. CENP-B binds a novel centromeric sequence in the Asian mouse Mus caroli. Mol. Cell. Biol. 15:4009–4020.
   PubMedGoogle Scholar
• Kipling, D., H. E. Wilson, A. R. Mitchell, B. A. Taylor, and H. J. Cooke. 1994. Mouse centromere mapping using oligonucleotide probes that detect variants of the minor satellite. Chromosomal 103:46–55.
   PubMedGoogle Scholar
• Kurnit, D. M., and J. J. Maio. 1973. Subnuclear redistribution of DNA species in confluent and growing mammalian cells. Chromosoma 42:23–36.
   PubMedGoogle Scholar
• Lechner, J., and J. Carbon. 1991. A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64:717–725.
   PubMed Web of Science ®Google Scholar
• Machamer, C. E., and J. K. Rose. 1987. A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi region. J. Cell Biol. 105:1205–1214.
   PubMedGoogle Scholar
• Masumoto, H. Personal communication.
   Google Scholar
• Masumoto, H., H. Masukata, Y. Muro, N. Nozaki, and T. Okazaki. 1989. A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite. J. Cell Biol. 109:1963–1973.
   PubMed Web of Science ®Google Scholar
• Masumoto, H., K. Yoda, M. Ikeno, K. Kitagawa, Y. Muro, and T. Okazaki. 1993. Properties of CENP-B and its target sequence in a satellite DNA. NATO ASI Ser. Ser. H 72:31–43.
   Google Scholar
• Matera, A. G., and D. C. Ward. 1992. Oligonucleotide probes for the analysis of specific repetitive DNA sequences by fluorescence in situ hybridization. Hum. Mol. Genet. 1:535–539.
   PubMed Web of Science ®Google Scholar
• Middleton, K., and J. Carbon. 1994. KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc. Natl. Acad. Sci. USA 91:7212–7216.
   PubMedGoogle Scholar
• Muro, Y., H. Masumoto, T. Okazaki, and M. Ohashi. 1991. Purification of a human centromere antigen (CENP-B) and application of DNA immunopre-cipitation to quantitative assay for anti-CENP-B antibodies. J. Invest. Dermatol. 97:378–380.
   PubMedGoogle Scholar
• Muro, Y., H. Masumoto, K. Yoda, N. Nozaki, M. Ohashi, and T. Okazaki. 1992. Centromere protein B assembles human centromeric a-satellite DNA at the 17-bp sequence, CENP-B box. J. Cell Biol. 116:585–596.
   PubMedGoogle Scholar
• Nicol, L., and P. Jeppesen. 1994. Human autoimmune sera recognize a conserved 26 kD protein associated with mammalian heterochromatin that is homologous to heterochromatin protein 1 of Drosophila. Chromosome Res. 2:245–253.
   PubMed Web of Science ®Google Scholar
• Ohashi, H., K. Wakui, K. Ogawa, T. Okano, N. Niikawa, and Y. Fukushima. 1994. A stable acentric chromosome: possible existence of an intercalary ancient centromere at distal 8p. Am. J. Hum. Genet. 55:1202–1208.
   PubMedGoogle Scholar
• Palmer, D. K., and R. L. Margolis. 1985. Kinetochore components recognized by human autoantibodies are present on mononucleosomes. Mol. Cell. Biol. 5:173–186.
   PubMedGoogle Scholar
• Pankov, R., M. Lemieux, and R. Hancock. 1990. An antigen located in the kinetochore region in metaphase and on polar microtubule ends in the midbody region in anaphase, characterized using a monoclonal antibody. Chromosoma 99:95–101.
   PubMedGoogle Scholar
• Pfarr, C. M., M. Coue, P. M. Grissom, T. S. Hays, M. E. Porter, and J. R. McIntosh. 1990. Cytoplasmic dynein is localized to kinetochores during mitosis. Nature (London) 345:263–265.
   PubMedGoogle Scholar
• Pluta, A. F. Unpublished data.
   Google Scholar
• Pluta, A. F., N. Saitoh, I. Goldberg, and W. C. Earnshaw. 1992. Identification of a subdomain of CENP-B that is necessary and sufficient for targeting to the human centromere. J. Cell Biol. 116:1081–1093.
   PubMedGoogle Scholar
• Rosenberg, H., M. Singer, and M. Rosenberg. 1978. Highly reiterated sequences of SIMIANSIMIANSIMIANSIMIANSIMIAN. Science 200:394–402.
   PubMedGoogle Scholar
• Saitoh, H., J. E. Tomkiel, C. A. Cooke, H. R. Ratrie, M. Maurer, N. F. Rothfield, and W. C. Earnshaw. 1992. CENP-C., an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70:115–125.
   PubMedGoogle Scholar
• Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Segal, S., M. Garner, M. F. Singer, and M. Rosenberg. 1976. In situ hybridization of repetitive monkey genome sequences isolated from defective simian virus 40 DNA. Cell 9:247–257.
   PubMedGoogle Scholar
• Singer, D. S. 1979. Arrangement of a highly repeated DNA sequence in the genome and chromatin of the African green monkey. J. Biol. Chem. 254:5506–5514.
   PubMed Web of Science ®Google Scholar
• Steuer, E. R., L. Wordeman, T. A. Schroer, and M. P. Sheetz. 1990. Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature (London) 345:266–268.
   PubMedGoogle Scholar
• Sullivan, K. F., and C. A. Glass. 1991. CENP-B is a highly conserved mammalian centromere protein with homology to the helix-loop-helix family of proteins. Chromosoma 100:360–370.
   PubMed Web of Science ®Google Scholar
• Tyler-Smith, C., and W. R. A. Brown. 1987. Structure of the major block of alphoid satellite DNA on the human Y chromosome. J. Mol. Biol. 195:457–470.
   PubMedGoogle Scholar
• Voullaire, L. E., H. R. Slater, V. Petrovic, and K. H. A. Choo. 1993. A functional marker centromere with no detectable alpha-satellite, satellite III, or CENP-B protein: activation of a latent centromere? Am. J. Hum. Genet. 52:1153–1163.
   Google Scholar
• Warburton, P. E., J. S. Waye, and H. S. Willard. 1993. Nonrandom localization of recombination events in human alpha satellite repeat unit variants: implications for higher-order structural characteristics within centromeric heterochromatin. Mol. Cell. Biol. 13:6520–6529.
   PubMedGoogle Scholar
• Waye, J. S., and H. Willard. 1986. Structure, organization, and sequence of alpha satellite DNA from human chromosome 17: evidence for evolution by unequal crossing-over and an ancestor pentamer repeat shared with the human X chromosome. Mol. Cell. Biol. 6:3156–3165.
   PubMedGoogle Scholar
• Willard, H. F. 1990. Centromeres of mammalian chromosomes. Trends Genet. 6:410–416.
   PubMed Web of Science ®Google Scholar
• Wong, A. K. C., and J. B. Rattner. 1988. Sequence organization and cyto-logical localization of the minor satellite of mouse. Nucleic Acids Res. 16:11645–11661.
   PubMed Web of Science ®Google Scholar
• Wordeman, L., and T. J. Mitchison. 1995. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128:95–105.
   PubMed Web of Science ®Google Scholar
• Yen, T. J., D. A. Compton, W. C. Earnshaw, and D. W. Cleveland. 1991. CENP-E, a human centromere associated protein released from chromosomes at the onset of anaphase. EMBO J. 10:1245–1991.
   PubMed Web of Science ®Google Scholar
• Yoda, K., K. Kitagawa, H. Masumoto, Y. Muro, and T. Okazaki. 1992. A human centromere protein, CENP-B, has a DNA binding domain containing four potential a helices at the NH2 terminus, which is separable from dimerizing activity. J. Cell Biol. 119:1413–1427.
   PubMed Web of Science ®Google Scholar
• Yoda, K., T. Nakamura, H. Masumoto, N. Suzuki, K. Kitagawa, M. Nakano, A. Shinjo, and T. Okazaki. 1996. Centromere protein B of African green monkey cells: gene structure, cellular expression, and centromeric localization. Mol. Cell. Biol. 16:5169–5177.
   PubMedGoogle Scholar