2
Views
73
CrossRef citations to date
0
Altmetric
Research Article

Residues in the WD Repeats of Tup1 Required for Interaction with α2

&
Pages 6023-6028 | Received 04 Apr 1997, Accepted 10 Jun 1997, Published online: 29 Mar 2023

REFERENCES

  • Braun, B., and A. D. Johnson. 1997. The transcriptional repressor TUP1 controls filament formation in the pathogenic yeast Candida albicans. Science 277:105–109.
  • Carlson, M., and D. Botstein. 1982. Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell 28:145–154.
  • Duronio, R. J., J. I. Gordon, and M. S. Boguski. 1992. Comparative analysis of the þ transducin family with identification of several new members including PWP1, a nonessential gene of Saccharomyces cerevisiae that is divergently transcribed from NMT1. Proteins 13:41–56.
  • Elledge, S. J., Z. Zhou, J. B. Allen, and T. A. Navas. 1993. DNA damage and cell cycle regulation of ribonucleotide reductase. Bioessays 15:333.
  • Garcia-Higuera, I., J. Fenoglio, Y. Li, C. Lewis, M. P. Panchenko, O. Reiner, T. F. Smith, and E. J. Neer. 1996. Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein þ subunit. Biochemistry 35:13985–13994.
  • Gaudet, R., A. Bohm, and P. B. Sigler. 1996. Crystal structure at 2.4 Angstrom resolution of the complex of transducin þμ and its regulator, phosducin. Cell 87:577–588.
  • Guarente, L., and E. Hoar. 1984. Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the TATA box. Proc. Natl. Acad. Sci. USA 81:7860–7864.
  • Guarente, L., and M. Ptashne. 1981. Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 78:2199–2203.
  • Hall, M. N., and A. D. Johnson. 1987. Homeo domain of the yeast repressor a2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science 237:1007–1012.
  • Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267–272.
  • Johnson, A. D., and I. Herskowitz. 1985. A repressor (MATa2 product) and its operator control expression of a set of cell type specific genes in yeast. Cell 42:237–247.
  • Johnson, S. 1991. Structure and function analysis of the yeast CDC4 gene product. Ph.D. thesis. University of Washington, Seattle.
  • Keleher, C. A., M. J. Redd, J. Schultz, M. Carlson, and A. D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:709–719.
  • Komachi, K., and A. D. Johnson. Unpublished data.
  • Komachi, K., M. J. Redd, and A. D. Johnson. 1994. The WD repeats of Tup1 interact with the homeodomain protein a2. Genes Dev. 8:2857–2867.
  • Kunkel, T. A., J. D. Roberts, and R. A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154:367–382.
  • Lambright, D. G., J. Sondek, A. Bohm, N. P. Skiba, H. E. Hamm, and P. B. Sigler. 1996. The 2.0 A crystal structure of a heterotrimeric G protein. Nature 379:311–319.
  • Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Muhlrad, D., R. Hunter, and R. Parker. 1992. A rapid method for localized mutagenesis of yeast genes. Yeast 8:79–82.
  • Mukai, Y., S. Harashima, and Y. Oshima. 1991. AAR1/TUP1 protein, with a structure similar to that of the þ subunit of G proteins, is required for a1-a2 and a2 repression in cell type control of Saccharomyces cerevisiae. Mol. Cell. Biol. 11:3773–3779.
  • Neer, E. J., C. J. Schmidt, R. Nambudripad, and T. F. Smith. 1994. The ancient regulatory-protein family of WD-repeat proteins. Nature 371:297–300.
  • Neer, E. J., and T. F. Smith. 1996. G protein heterodimers: new structures propel new questions. Cell 84:175–178.
  • Schnell, R., and J. Rine. 1986. A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 6:494–501.
  • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19–27.
  • Siliciano, P. G., and K. Tatchell. 1984. Transcription and regulatory signals at the mating type locus in yeast. Cell 37:969–978.
  • Sondek, J., A. Bohm, D. G. Lambright, H. E. Hamm, and P. B. Sigler. 1996. Crystal structure of a GA protein þμ dimer at 2.1Å resolution. Nature 379:369–374.
  • Tatchell, K., K. A. Nasmyth, B. D. Hall, C. Astell, and M. Smith. 1981. In vitro mutation analysis of the mating-type locus in yeast. Cell 27:25–35.
  • Trumbly, R. J. 1992. Glucose repression in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 6:15–21.
  • Tzamarias, D., and K. Struhl. 1994. Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex. Nature 369:758–761.
  • van der Voorn, L., and H. L. Ploegh. 1992. The WD-40 repeat. FEBS Lett. 307:131–134.
  • Vershon, A. K., Y. Jin, and A. D. Johnson. 1995. A homeo domain protein lacking specific side chains of helix 3 can still bind DNA and direct transcriptional repression. Genes Dev. 9:182–192.
  • Vershon, A. K., and A. D. Johnson. 1993. A short, disordered protein region mediates interactions between the homeodomain of the yeast a2 protein and the MCM1 protein. Cell 72:105–112.
  • Wall, M. A., D. E. Coleman, E. Lee, J. A. Iniguez-Lluhi, B. A. Posner, A. G. Gilman, and S. R. Sprang. 1995. The structure of the G protein heterotrimer Gia1þ1μ2. Cell 83:1047–1058.
  • Yamashiro, C. T., D. J. Ebbole, B.-U. Lee, R. E. Brown, C. Bourland, L. Madi, and C. Yanofsky. 1996. Characterization of rco-1 of Neurospora crassa, a pleiotropic gene affecting growth and development that encodes a homolog of Tup1 of Saccharomyces cerevisiae. Mol. Cell. Biol. 16:6218–6228.
  • Zhou, Z., and S. J. Elledge. 1992. Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics 131:851–856.
  • Zitomer, R. S., and C. V. Lowry. 1992. Regulation of gene expression by oxygen in Saccharomyces cerevisiae. Microbiol. Rev. 56:1–11.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.