Recruitment of the Putative Transcription-Repair Coupling Factor CSB/ERCC6 to RNA Polymerase II Elongation Complexes

References

• Aladjem, M. I., M. Groudine, L. L. Brody, E. S. Dieken, R. E. Fournier, G. M. Wahl, and E. M. Epner. 1995. Participation of the human beta-globin locus control region in initiation of DNA replication. Science 270:815–819.
   PubMedGoogle Scholar
• Auble, D. T., K. E. Hansen, C. G. Mueller, W. S. Lane, J. Thorner, and S. Hahn. 1994. Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes Dev. 8:1920–1934.
   PubMed Web of Science ®Google Scholar
• Balajee, A. S., A. May, G. L. Dianov, E. C. Friedberg, and V. A. Bohr. 1997. Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc. Natl. Acad. Sci. USA 94:4306–4311.
   PubMedGoogle Scholar
• Bell, S. P., R. Kobayashi, and B. Stillman. 1993. Yeast origin recognition complex functions in transcription silencing and DNA replication. Science 262:1844–1849.
   PubMed Web of Science ®Google Scholar
• Bohr, V. A., C. A. Smith, D. S. Okumoto, and P. C. Hanawalt. 1985. DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40:359–369.
   PubMed Web of Science ®Google Scholar
• Bunick, D., R. Zandomeni, S. Ackerman, and R. Weinmann. 1982. Mechanism of RNA polymerase II-specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts. Cell 29:877–886.
   PubMed Web of Science ®Google Scholar
• Cooper, P. K., T. Nouspikel, S. G. Clarckson, and S. A. Leadon. 1997. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 275:990–993.
   PubMedGoogle Scholar
• Dignam, J. D., P. L. Martin, B. S. Shastry, and R. G. Roeder. 1983. Eukaryotic gene transcription with purified components. Methods Enzymol. 101:582–598.
   PubMed Web of Science ®Google Scholar
• Drapkin, R., J. T. Reardon, A. Ansari, J. C. Huang, L. Zawel, K. Ahn, A. Sancar, and D. Reinberg. 1994. Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II. Nature 368:769–772.
   PubMed Web of Science ®Google Scholar
• Foss, M., F. J. McNally, P. Laurenson, and J. Rine. 1993. Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae. Science 262:1838–1844.
   PubMed Web of Science ®Google Scholar
• Frenkel, K., M. S. Goldstein, N. J. Duker, and G. W. Teebor. 1981. Identification of the cis-thymine glycol moiety in oxidized deoxyribonucleic acid. Biochemistry 20:750–754.
   PubMed Web of Science ®Google Scholar
• Friedberg, E. C. 1996. Relationships between DNA repair and transcription. Annu. Rev. Biochem. 65:15–42.
   PubMed Web of Science ®Google Scholar
• Guzder, S. N., Y. Habraken, P. Sung, L. Prakash, and S. Prakash. 1996. RAD26, the yeast homolog of human Cockayne’s syndrome group B gene, encodes a DNA-dependent ATPase. J. Biol. Chem. 271:18314–18317.
   PubMedGoogle Scholar
• Henning, K. A., L. Li, N. Iyer, L. D. McDaniel, M. S. Reagan, R. Legerski, R. A. Schultz, M. Stefanini, A. R. Lehmann, L. V. Mayne et al. 1995. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82:555–564.
   PubMed Web of Science ®Google Scholar
• Hoeijmakers, J. H. J., J.-M. Egly, and W. Vermeulen. 1996. TFIIH: a key component in multiple DNA transactions. Curr. Opin. Genet. Dev. 6:26–33.
   PubMed Web of Science ®Google Scholar
• Holstege, F. C., D. Tantin, M. Carey, P. C. van der Vliet, and H. T. Timmers. 1995. The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA. EMBO J. 14:810–819.
   PubMed Web of Science ®Google Scholar
• Holstege, F. C., P. C. van der Vliet, and H. T. Timmers. 1996. Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH. EMBO J. 15:1666–1677.
   PubMedGoogle Scholar
• Humbert, S., H. van Vuuren, Y. Lutz, J. H. Hoeijmakers, J. M. Egly, and V. Moncollin. 1994. p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair. EMBO J. 13:2393–2398.
   PubMedGoogle Scholar
• Iyer, N., M. S. Reagan, K. J. Wu, B. Canagarajah, and E. C. Friedberg. 1996. Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. Biochemistry 35:2157–2167.
   PubMedGoogle Scholar
• Kadesch, T. R., and M. J. Chamberlin. 1982. Studies of in vitro transcription by calf thymus RNA polymerase II using a novel duplex DNA template. J. Biol. Chem. 257:5286–5295.
   PubMed Web of Science ®Google Scholar
• Kerppola, T. K., and C. M. Kane. 1990. Analysis of the signals for transcription termination by purified RNA polymerase II. Biochemistry 29:269–278.
   PubMedGoogle Scholar
• Klemm, R. D., R. J. Austin, and S. P. Bell. 1997. Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex. Cell 88:493–502.
   PubMed Web of Science ®Google Scholar
• Kogoma, T., G. W. Cadwell, K. G. Barnard, and T. Asai. 1996. The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair. J. Bacteriol. 178:1258–1264.
   PubMedGoogle Scholar
• Kow, Y. W., S. S. Wallace, and B. Van Houten. 1990. UvrABC nuclease complex repairs thymine glycol, an oxidative DNA base damage. Mutat. Res. 235:147–156.
   PubMedGoogle Scholar
• Leadon, S. A., S. L. Barbee, and A. B. Dunn. 1995. The yeast RAD2, but not RAD1, gene is involved in the transcription-coupled repair of thymine glycols. Mutat. Res. 337:169–178.
   PubMedGoogle Scholar
• Leadon, S. A., and P. K. Cooper. 1993. Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc. Natl. Acad. Sci. USA 90:10499–10503.
   PubMed Web of Science ®Google Scholar
• Leadon, S. A., and D. A. Lawrence. 1992. Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase II. J. Biol. Chem. 267:23175–23182.
   PubMed Web of Science ®Google Scholar
• Lehmann, A. R. 1995. Nucleotide excision repair and the link with transcription. Trends Biochem. Sci. 20:402–405.
   PubMed Web of Science ®Google Scholar
• Marinoni, J. C., R. Roy, W. Vermeulen, P. Miniou, Y. Lutz, G. Weeda, T. Seroz, D. M. Gomez, J. H. Hoeijmakers, and J. M. Egly. 1997. Cloning and characterization of p52, the fifth subunit of the core of the transcription/ DNA repair factor TFIIH. EMBO J. 16:1093–1102.
   PubMedGoogle Scholar
• Mayne, L. V., and A. R. Lehmann. 1982. Failure of RNA synthesis to recover after UV-radiation: an early defect in cells from individuals with Cockayne’s syndrome and xeroderma pigmentosum. Cancer Res. 42:1473–1478.
   PubMed Web of Science ®Google Scholar
• Mellon, I., V. A. Bohr, C. A. Smith, and P. C. Hanawalt. 1986. Preferential DNA repair of an active gene in human cells. Proc. Natl. Acad. Sci. USA 83:8878–8882.
   PubMed Web of Science ®Google Scholar
• Mellon, I., and P. C. Hanawalt. 1989. Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand. Nature 342:95–98.
   PubMed Web of Science ®Google Scholar
• Mellon, I., G. Spivak, and P. C. Hanawalt. 1987. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51:241–249.
   PubMed Web of Science ®Google Scholar
• Milbrandt, J. D., N. H. Heintz, W. C. White, S. M. Rothman, and J. L. Hamlin. 1981. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Proc. Natl. Acad. Sci. USA 78:6043–6047.
   PubMedGoogle Scholar
• Moore, M. J., C. C. Query, and P. A. Sharp. 1993. Splicing of precursors to messenger RNA’s by the spliceosome. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Neer, E. J., C. J. Schmidt, R. Nambudripad, and T. F. Smith. 1994. The ancient regulatory-protein family of WD-repeat proteins. Nature 371:297–300. (Erratum, 371:812, 1994.)
   PubMed Web of Science ®Google Scholar
• Ohba, R., K. Matsumoto, and Y. Ishimi. 1996. Induction of DNA replication by transcription in the region upstream of the human c-myc gene in a model replication system. Mol. Cell. Biol. 16:5754–5763.
   PubMedGoogle Scholar
• O’Neill, E. A., C. Fletcher, C. R. Burrow, N. Heintz, R. G. Roeder, and T. J. Kelly. 1988. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science 241:1210–1213.
   PubMedGoogle Scholar
• Pan, G., and J. Greenblatt. 1994. Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site. J. Biol. Chem. 269:30101–30104.
   PubMed Web of Science ®Google Scholar
• Parvin, J. D., and P. A. Sharp. 1993. DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. Cell 73:533–540.
   PubMed Web of Science ®Google Scholar
• Reinberg, D., and R. G. Roeder. 1987. Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. J. Biol. Chem. 262:3310–3321.
   PubMed Web of Science ®Google Scholar
• Sancar, A. 1996. DNA excision repair. Annu. Rev. Biochem. 65:43–81.
   PubMed Web of Science ®Google Scholar
• Sawadogo, M., and R. G. Roeder. 1984. Energy requirement for specific transcription initiation by the human RNA polymerase II system. J. Biol. Chem. 259:5321–5326.
   PubMed Web of Science ®Google Scholar
• Schaeffer, L., V. Moncollin, R. Roy, A. Staub, M. Mezzina, A. Sarasin, G. Weeda, J. H. Hoeijmakers, and J. M. Egly. 1994. The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor. EMBO J. 13:2388–2392.
   PubMed Web of Science ®Google Scholar
• Schaeffer, L., R. Roy, S. Humbert, V. Moncollin, W. Vermeulen, J. H. Hoeijmakers, P. Chambon, and J. M. Egly. 1993. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science 260:58–63.
   PubMed Web of Science ®Google Scholar
• Schmickel, R. D., E. H. Y. Chu, J. E. Trosko, and C. C. Chang. 1977. Cockayne syndrome: a cellular sensitivity to ultraviolet light. Pediatrics 60:135–139.
   PubMed Web of Science ®Google Scholar
• Segil, N., M. Guermah, A. Hoffmann, R. G. Roeder, and N. Heintz. 1996. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes Dev. 10:2389–2400.
   PubMed Web of Science ®Google Scholar
• Selby, C. P., and A. Sancar. 1991. Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor. Proc. Natl. Acad. Sci. USA 88:8232–8236.
   PubMed Web of Science ®Google Scholar
• Selby, C. P., and A. Sancar. 1997. Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. J. Biol. Chem. 272:1885–1890.
   PubMed Web of Science ®Google Scholar
• Selby, C. P., and A. Sancar. 1993. Molecular mechanism of transcriptionrepair coupling. Science 260:53–58.
   PubMed Web of Science ®Google Scholar
• Sweder, K. S., and P. C. Hanawalt. 1992. Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription. Proc. Natl. Acad. Sci. USA 89:10696–10700.
   PubMedGoogle Scholar
• Tantin, D., and M. Carey. 1994. A heteroduplex template circumvents the energetic requirement for ATP during activated transcription by RNA polymerase II. J. Biol. Chem. 269:17397–17400.
   PubMedGoogle Scholar
• Tantin, D., and M. Carey. Unpublished data.
   Google Scholar
• Thompson, N. E., D. B. Aronson, and R. R. Burgess. 1990. Purification of eukaryotic RNA polymerase II by immunoaffinity chromatography. Elution of active enzyme with protein stabilizing agents from a polyol-responsive monoclonal antibody. J. Biol. Chem. 265:7069–7077.
   PubMedGoogle Scholar
• Timmers, H. T. 1994. Transcription initiation by RNA polymerase II does not require hydrolysis of the beta-gamma phosphoanhydride bond of ATP. EMBO J. 13:391–399.
   PubMedGoogle Scholar
• Troelstra, C., A. van Gool, J. de Wit, W. Vermeulen, D. Bootsma, and J. H. Hoeijmakers. 1992. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne’s syndrome and preferential repair of active genes. Cell 71:939–953.
   PubMed Web of Science ®Google Scholar
• van Gool, A. J., R. Verhage, S. M. Swagemakers, P. van de Putte, J. Brouwer, C. Troelstra, D. Bootsma, and J. H. Hoeijmakers. 1994. RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6. EMBO J. 13:5361–5369.
   PubMed Web of Science ®Google Scholar
• van Hoffen, A., A. T. Natarajan, L. V. Mayne, A. A. van Zeeland, L. H. F. Mullenders, and J. Venema. 1993. Deficient repair of the transcribed strand of active genes in Cockayne’s syndrome cells. Nucleic Acids Res. 21:5890–5895.
   PubMed Web of Science ®Google Scholar
• van Oosterwijk, M. F., A. Versteeg, R. Filon, A. A. van Zeeland, and L. H. Mullenders. 1996. The sensitivity of Cockayne’s syndrome cells to DNA- damaging agents is not due to defective transcription-coupled repair of active genes. Mol. Cell. Biol. 16:4436–4444.
   PubMedGoogle Scholar
• Venema, J., L. H. Mullenders, A. T. Natarajan, A. A. van Zeeland, and L. V. Mayne. 1990. The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc. Natl. Acad. Sci. USA 87:4707–4711.
   PubMed Web of Science ®Google Scholar
• Wang, W., M. Carey, and J. D. Gralla. 1992. Polymerase II promoter activation: closed complex formation and ATP-driven start site opening. Science 255:450–453.
   PubMed Web of Science ®Google Scholar
• Wang, Z., S. Buratowski, J. Q. Svejstrup, W. J. Feaver, X. Wu, R. D. Kornberg, T. F. Donahue, and E. C. Friedberg. 1995. The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription. Mol. Cell. Biol. 15:2288–2293.
   PubMedGoogle Scholar
• Wang, Z., J. Q. Svejstrup, W. J. Feaver, X. Wu, R. D. Kornberg, and E. C. Friedberg. 1994. Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast. Nature 368:74–76.
   PubMedGoogle Scholar
• Zawel, L., K. P. Kumar, and D. Reinberg. 1995. Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9:1479–1490.
   PubMedGoogle Scholar