8
Views
36
CrossRef citations to date
0
Altmetric
Research Article

Concerted Activity of Host Cell Factor Subregions in Promoting Stable VP16 Complex Assembly and Preventing Interference by the Acidic Activation Domain

, &
Pages 7108-7118 | Received 25 Jun 1997, Accepted 08 Sep 1997, Published online: 29 Mar 2023

References

  • Ace, C. I., M. A. Dalrymple, F. H. Ramsay, V. G. Preston, and C. M. Preston. 1988. Mutational analysis of the herpes simplex virus type 1 trans-inducing factor Vmw65. J. Gen. Virol. 69:2595–2605.
  • apRhys, C. M., D. M. Ciufo, E. A. O’Neill, T. J. Kelly, and G. S. Hayward. 1989. Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III. J. Virol. 63:2798–2812.
  • Bork, P., and R. F. Doolittle. 1994. Drosophila kelch motif is derived from a common enzyme fold. J. Mol. Biol. 236:1277–1282.
  • Breim, A., K. Ohbo, and H. Scholer. 1997. The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain. Mol. Cell. Biol. 17:154–162.
  • Campbell, M. E., J. W. Palfreyman, and C. M. Preston. 1984. Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription. J. Mol. Biol. 180:1–19.
  • Cepek, K. L., D. L. Chasman, and P. A. Sharp. 1996. Sequence-specific DNA binding of the B-cell-specific coactivator OCA-B. Genes Dev. 10:2079–2088.
  • Cousens, D. J., R. Greaves, C. R. Goding, and P. O’Hare. 1989. The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins. EMBO J. 8:2337–2342.
  • Eichinger, L., L. Bomblies, J. Vanderkerckhove, M. Schleicher, and J. Gettemans. 1996. A novel type of protein kinase phosphorylates actin in the actin-fragmin complex. EMBO J. 15:5547–5556.
  • Gerster, T., and R. G. Roeder. 1988. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc. Natl. Acad. Sci. USA 85:6347–6351.
  • Greaves, R., and P. O’Hare. 1989. Separation of requirements for protein- DNA complex assembly from those for functional activity in the herpes simplex virus regulatory protein Vmw65. J. Virol. 63:1641–1650.
  • Greaves, R. F., and P. O’Hare. 1990. Structural requirements in the herpes simplex virus type 1 transactivator Vmw65 for interaction with the cellular octamer-binding protein and target TAATGARAT sequences. J. Virol. 64:2716–2724.
  • Gstaiger, M., O. Georgiev, H. van Leeuwen, P. van der Vliet, and W. Schaffner. 1996. The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J. 15:2781–2790.
  • Hayes, S., and P. O’Hare. 1993. Mapping of a major surface exposed site in the herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly. J. Virol. 67:852–862.
  • He, X., R. Gerrero, D. M. Simmons, R. E. Park, C. R. Lin, L. W. Swanson, and M. G. Rosenfeld. 1991. Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule Po. Mol. Cell. Biol. 11:1739–1744.
  • Herr, W., R. A. Sturm, R. G. Clerc, L. M. Corcoran, D. Baltimore, P. A. Sharpe, H. A. Ingraham, M. G. Rosenfeld, M. Finney, G. Ruvken, and H. R. Horvitz. 1988. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2:1513–1516.
  • Hill, C. S., J. Wynne, and R. Treisman. 1994. Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain. EMBO J. 13:5421–5432.
  • Hinkley, C. S., J. F. Martin, D. Leibham, and M. Perry. 1992. Sequential expression of multiple POU proteins during amphibian early development. Mol. Cell. Biol. 12:638–649.
  • Ito, N., S. E. Philips, K. D. S. Yadav, and P. F. Knowles. 1994. Crystal structure of a free radical enzyme, galactose oxidase. J. Mol. Biol. 238:794–814.
  • Johnson, W. A., and J. Hirsh. 1990. Binding of a Drosophila POU-domain protein to a sequence element regulating gene expression in specific dopaminergic neurons. Nature 343:467–470.
  • Katan, M., A. Haigh, C. P. Verrijzer, P. C. van der Vliet, and P. O’Hare. 1990. Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex. Nucleic Acids Res. 18:6871–6880.
  • Kemler, I., E. Bucher, K. Seipel, M. M. Muller-Immergluck, and W. Schaffner. 1991. Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration. Nucleic Acids Res. 19:237–242.
  • Kristie, T. M., J. H. LeBowitz, and P. A. Sharp. 1989. The octamer-binding proteins form multi-protein-DNA complexes with the HSV alpha TIF regulatory protein. EMBO J. 8:4229–4238.
  • Kristie, T. M., J. L. Pomerantz, T. C. Twomey, S. A. Parent, and P. A. Sharp. 1995. The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides. J. Biol. Chem. 270:4387–4394.
  • Kristie, T. M., and P. A. Sharp. 1993. Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus α-trans-induction factor (VP16). J. Biol. Chem. 268:6525–6534.
  • Lai, J. S., M. A. Cleary, and W. Herr. 1992. A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain. Genes Dev. 6:2058–2065.
  • Lefstin, J. A., J. R. Thomas, and K. R. Yamamoto. 1994. Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions. Genes Dev. 8:2842–2856.
  • Luo, Y., and R. G. Roeder. 1995. Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol. Cell. Biol. 15:4115–4124.
  • Mackem, S., and B. Roizman. 1982. Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes. J. Virol. 44:939–949.
  • Monuki, E. S., R. Kuhn, and G. Lemke. 1993. Repression of the myelin P0 gene by the POU transcription factor SCIP. Mech. Dev. 42:15–32.
  • Morris, P. J., T. Theil, C. J. A. Ring, K. A. Lillycrop, T. Moroy, and D. S. Latchman. 1994. The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. Mol. Cell. Biol. 14:6907–6914.
  • O’Hare, P. 1993. The virion transactivator of herpes simplex. Semin. Virol. 4:145–155.
  • O’Hare, P., and C. R. Goding. 1988. Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation. Cell 52:435–445.
  • O’Hare, P., C. R. Goding, and A. Haigh. 1988. Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression. EMBO J. 7:4231–4238.
  • O’Reilly, D., O. Hanscombe, and P. O’Hare. 1997. A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II. EMBO J. 16:2420–2430.
  • Pfisterer, P., S. Zwilling, J. Hess, and T. Wirth. 1995. Functional characterisation of the murine homolog of the B-cell-specific coactivator BOB.1/ OBF.1. J. Biol. Chem. 270:29870–29880.
  • Pomerantz, J. L., T. M. Kristie, and P. A. Sharp. 1992. Recognition of the surface of a homeo domain protein. Genes Dev. 6:2047–2057.
  • Post, L. E., S. Mackem, and B. Roizman. 1981. Regulation of alpha genes of herpes simplex virus: expression of chimeric genes produced by fusion of thymidine kinase with alpha gene promoters. Cell 24:555–565.
  • Preston, C. M., M. G. Cordingley, and N. D. Stow. 1984. Analysis of DNA sequences which regulate the transcription of a herpes simplex virus immediate early gene. J. Virol. 50:708–716.
  • Preston, C. M., M. C. Frame, and M. E. Campbell. 1988. A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence. Cell 52:425–434.
  • Rosenfeld, M. 1991. POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev. 5:897–907.
  • Ruvkun, G., and M. Finney. 1991. Regulation of transcription and cell identity by POU domain proteins. Cell 64:475–476.
  • Sadowski, I., J. Ma, S. Triezenberg, and M. Ptashne. 1988. GAL4-VP16 is an unusually potent transcriptional activator. Nature 335:563–564.
  • Simmen, K. A., A. Newell, M. Robinson, J. S. Mills, G. Canning, R. Handa, K. Parkes, N. Borkakoti, and R. Jupp. 1997. Protein interactions in the herpes simplex virus type 1 VP16-induced complex: VP16 peptide inhibition and mutational analysis of host cell factor requirements. J. Virol. 71:3886–3894.
  • Stern, S., and W. Herr. 1991. The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain. Genes Dev. 5:2555–2566.
  • Stern, S., M. Tanaka, and W. Herr. 1989. The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature 341:624–630.
  • Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497–506.
  • Thompson, C., and S. McKnight. 1992. Anatomy of an enhancer. Trends Genet. 8:232–236.
  • Triezenberg, S. J., K. L. LaMarco, and S. L. McKnight. 1988. Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16. Genes Dev. 2:730–742.
  • Verrijzer, C. P., J. van Oosterhout, and P. C. van der Vliet. 1992. The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins. Mol. Cell. Biol. 12:542–551.
  • Verrijzer, C. P., and P. C. van der Vliet. 1993. POU domain transcription factors. Biochim. Biophys. Acta 1173:1–21.
  • Walker, S., S. Hayes, and P. O’Hare. 1994. Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for the differential recognition by Vmw65 (VP16). Cell 79:841–852.
  • Wegner, M., D. W. Drolet, and M. G. Rosenfeld. 1993. POU-domain proteins: structure and function of developmental regulators. Curr. Opin. Cell Biol. 5:488–498.
  • Werstuck, G., and J. P. Capone. 1989. Mutational analysis of the herpes simplex virus trans-inducing factor Vmw65. Gene 75:213–224.
  • Wilson, A., M. G. Peterson, and W. Herr. 1995. The HCF repeat is an unusual proteolytic cleavage signal. Genes Dev. 9:2445–2458.
  • Wilson, A. C., M. A. Cleary, J. S. Lai, K. LaMarco, M. G. Peterson, and W. Herr. 1993. Combinatorial control of transcription: the herpes simplex virus VP16-induced complex. Cold Spring Harbor Symp. Quant. Biol. 58:167–178.
  • Wilson, A. C., K. LaMarco, M. G. Peterson, and W. Herr. 1993. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell 74:115–125.
  • Xiao, P., and J. P. Capone. 1990. A cellular factor binds to the herpes simplex virus type 1 transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1. Mol. Cell. Biol. 10:4974–4977.
  • Xue, F., and L. Cooley. 1993. Kelch encodes a component of intercellular bridges in Drosophila egg chambers. Cell 72:681–693.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.